Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.
IBB vs RSP: how they differ
IBB and RSP hold 0% of their weight in the same names, and IBB returned more over the year.
iShares Biotechnology ETF and Invesco S&P 500 Equal Weight ETF.
What they hold in common
By the books each fund has filed, IBB and RSP hold 0% of their money in the same securities at the same weight.
| Only in IBB | Only in RSP |
|---|---|
| VERTEX PHARMACEUTICALS 7.94% | Moderna Inc 0.58% |
| AMGEN INC 7.85% | Veeva Systems Inc 0.31% |
| GILEAD SCIENCES 7.44% | Zebra Technologies Corp 0.31% |
| REGENERON PHARMACEUTICALS 5.92% | Marathon Petroleum Corp 0.29% |
| ARGENX SE ADR 3.78% | Valero Energy Corp 0.29% |
| MODERNA 3.67% | Charles River Laboratories International 0.28% |
| NATERA 3.30% | Phillips 66 0.28% |
| REVOLUTION MEDICINES 2.87% | Salesforce Inc 0.28% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 10, 2026.
| IBB iShares Biotechnology ETF | RSP Invesco S&P 500 Equal Weight ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | Invesco |
| What it is | Biotechnology | S&P 500 equal weight |
| Total return, 1 year | +41.5% | +14.8% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +24.0 pts | −2.7 pts |
| Expense ratio | 0.44% | 0.20% |
| Already in the S&P 500 | 35.6% | 99.1% |
| Holdings | 233 | 506 |
IBB in plain words
IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Sep 10, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 233 positions, with the top ten at 47.5%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.
RSP in plain words
RSP is an index equity fund tracking the S&P 500 equal weight. Over the year to Sep 11, 2026 it returned +14.8% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.20% a year. By its holdings filed for Sep 10, 2026, 99% of the fund by weight is stocks the S&P 500 also holds, across 506 positions, with the top ten at 3.2%. It sat 3.5% below its high of Aug 14, 2026 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, IBB or RSP?
- In the year to Sep 13, 2026, with distributions reinvested, IBB returned +41.5% and RSP returned +14.8%, so IBB returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IBB or RSP?
- IBB charges 0.44% a year and RSP charges 0.20%, so RSP is cheaper. Fees come from each fund's prospectus.
- How much do IBB and RSP overlap with the S&P 500?
- By their latest filed holdings, 36% of IBB and 99% of RSP by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBB against RSP, data as of Sep 13, 2026. https://etfiq.com/compare/any/ibb-vs-rsp Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources