Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.
VPU vs XBI: how they differ
VPU and XBI hold 0% of their weight in the same names, and XBI returned more over the year.
Vanguard Utilities Index Fund and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, VPU and XBI hold 0% of their money in the same securities at the same weight.
| Only in VPU | Only in XBI |
|---|---|
| NextEra Energy Inc 11.84% | MODERNA INC 2.87% |
| Southern Co/The 6.70% | TWIST BIOSCIENCE CORP 1.81% |
| Duke Energy Corp 6.31% | HALOZYME THERAPEUTICS INC 1.47% |
| Constellation Energy Corp 5.86% | NATERA INC 1.46% |
| American Electric Power Co Inc 4.47% | KYMERA THERAPEUTICS INC 1.45% |
| Sempra 3.85% | TRAVERE THERAPEUTICS INC 1.40% |
| Dominion Energy Inc 3.78% | ROIVANT SCIENCES LTD 1.39% |
| Vistra Corp 3.59% | ORUKA THERAPEUTICS INC 1.38% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 10, 2026.
| VPU Vanguard Utilities Index Fund | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | Vanguard | State Street |
| What it is | Utilities | SPDR S&P Biotech |
| Total return, 1 year | +2.1% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | −15.4 pts | +46.5 pts |
| Expense ratio | 0.09% | 0.35% |
| Already in the S&P 500 | 90.1% | 8.5% |
| Holdings | 66 | 154 |
VPU in plain words
VPU is an index equity fund tracking the Utilities. Over the year to Sep 11, 2026 it returned +2.1% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.09% a year. By its holdings filed for May 31, 2026, 90% of the fund by weight is stocks the S&P 500 also holds, across 66 positions, with the top ten at 52.7%. It sat 9.8% below its high of Feb 27, 2026 on Sep 11, 2026.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Sep 10, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 15.9%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, VPU or XBI?
- In the year to Sep 13, 2026, with distributions reinvested, VPU returned +2.1% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, VPU or XBI?
- VPU charges 0.09% a year and XBI charges 0.35%, so VPU is cheaper. Fees come from each fund's prospectus.
- How much do VPU and XBI overlap with the S&P 500?
- By their latest filed holdings, 90% of VPU and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
Other comparisons
Where to next
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, VPU against XBI, data as of Sep 13, 2026. https://etfiq.com/compare/any/vpu-vs-xbi Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources