Data as of Oct 28, 2026.

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DYNF vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, DYNF returned +14.5% to XBI's +41.2%, and DYNF charges 0.26% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $42.7bn for iShares U.S. Equity Factor Rotation Active ETF and $10.3bn for State Street SPDR S&P Biotech ETF.

At a glance
+14.5%
DYNF total return, 1 year
+41.2%
XBI total return, 1 year
0.26%
DYNF expense ratio
0.35%
XBI expense ratio

Pair scorecard

DYNF costs 0.09 points a year less; their one-year returns differ by 26.7 points; DYNF is 4.1 times larger.

DYNF vs XBI: Differences, Returns & Fees
MeasureDYNFXBI
Return
Total return, 1 year+14.5%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksNo index, actively managedBiotech
Cost and size
Expense ratio0.26%0.35%
Net assets, as of Oct 27, 2026$42.7bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common2%
Top ten holdings, share of the fund40.7%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

2%

By the books each fund has filed, DYNF and XBI hold 2% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

2% in common

Positions both hold · largest shared weight first DYNF XBI
GILEAD SCIENCES 0.49% 1.60%
ABBVIE 0.46% 1.67%
REGENERON PHARMACEUTICALS 0.19% 1.48%
UNITED THERAPEUTICS 0.11% 1.71%
NEUROCRINE BIOSCIENCES 0.06% 1.38%
AMGEN INC 0.05% 1.68%
HALOZYME THERAPEUTICS 0.05% 1.75%
VERTEX PHARMACEUTICALS 0.05% 1.46%
BIOGEN 0.04% 1.75%
REVOLUTION MEDICINES 0.04% 1.31%
INSMED 0.03% 1.08%
ALNYLAM PHARMACEUTICALS 0.01% 1.29%
Only in one fund ↓
Only in DYNF
NVIDIA 8.15%
APPLE 8.14%
MICROSOFT 4.76%
AMAZON.COM INC 4.12%
JPMORGAN CHASE & CO 3.30%
EXXONMOBIL HOLDINGS CORP 2.99%
BROADCOM INC 2.46%
META PLATFORMS CLASS A 2.34%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
SPYRE THERAPEUTICS INC 1.67%
IOVANCE BIOTHERAPEUTICS INC 1.62%
ORUKA THERAPEUTICS INC 1.53%
TG THERAPEUTICS INC 1.51%
GRAIL INC 1.46%
Check overlap with more funds →

Side by side

DYNF iShares U.S. Equity Factor Rotation Active ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Actively managed Biotech
Total return, 1 year +14.5% +41.2%
Its benchmark over the same days +13.3% (PBUS) not measured
Gap to its benchmark +1.2 pts vs PBUS not measured
Expense ratio 0.26% 0.35%
Already in the S&P 500 94.8% 13.2%
Holdings 262 165
Net assets, as of Oct 27, 2026 $42.7bn $10.3bn

DYNF and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
DYNF

DYNF is actively managed and tracks no index. Over the year to Oct 28, 2026 it returned +14.5% with distributions reinvested, against +13.3% for its benchmark, the MSCI USA Index. The prospectus expense ratio is 0.26% a year. By its holdings published by its issuer for Oct 27, 2026, 95% of the fund by weight is stocks the S&P 500 also holds, across 262 positions, with the top ten at 40.7%.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are DYNF and XBI in the same category?
DYNF is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, DYNF or XBI?
In the year to Oct 28, 2026, with distributions reinvested, DYNF returned +14.5% and XBI +41.2%.
Which is cheaper, DYNF or XBI?
DYNF is cheaper, by 0.09 percentage points a year. That is about $9 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do DYNF and XBI overlap with the S&P 500?
By their latest filed holdings, 95% of DYNF and 13% of XBI by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, DYNF against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/dynf-vs-xbi

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