Data as of Oct 28, 2026.

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SCHX vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, SCHX returned +13.1% to XBI's +41.2%, and SCHX charges 0.03% to XBI's 0.35%.

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Net assets: $74.2bn on Aug 31, 2026 for Schwab U.S. Large-Cap ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+13.1%
SCHX total return, 1 year
+41.2%
XBI total return, 1 year
0.03%
SCHX expense ratio
0.35%
XBI expense ratio

Pair scorecard

SCHX costs 0.32 points a year less; their one-year returns differ by 28.1 points.

SCHX vs XBI: Differences, Returns & Fees
MeasureSCHXXBI
Return
Total return, 1 year+13.1%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksDow Jones U.S. Large-Cap Total Stock Market IndexBiotech
Cost and size
Expense ratio0.03%0.35%
Net assets, SCHX as of Aug 31, 2026 and XBI as of Oct 27, 2026$74.2bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common2%
Top ten holdings, share of the fund36.0%18%

Holdings in common uses holdings dated Aug 31, 2026 and Oct 27, 2026. Method

What they share

2%

By the books each fund has filed, SCHX and XBI hold 2% of their money in the same securities at the same weight. Holdings dated Aug 31, 2026 and Oct 27, 2026.

0 half 100%

half

2% in common

Positions both hold · largest shared weight first SCHX XBI
AbbVie Inc 0.65% 1.67%
Amgen Inc 0.33% 1.68%
Gilead Sciences Inc 0.26% 1.60%
Vertex Pharmaceuticals Inc 0.20% 1.46%
Regeneron Pharmaceuticals Inc 0.12% 1.48%
Moderna Inc 0.07% 2.24%
Natera Inc 0.07% 1.82%
Alnylam Pharmaceuticals Inc 0.05% 1.29%
Biogen Inc 0.05% 1.75%
Insmed Inc 0.04% 1.08%
United Therapeutics Corp 0.03% 1.71%
Incyte Corp 0.03% 1.35%
Only in one fund ↓
Only in SCHX
NVIDIA Corp 7.69%
Apple Inc 6.69%
Microsoft Corp 5.42%
Amazon.com Inc 3.66%
Alphabet Inc 2.86%
Broadcom Inc 2.52%
Alphabet Inc 2.28%
Meta Platforms Inc 1.81%
Only in XBI
TWIST BIOSCIENCE CORP 1.86%
HALOZYME THERAPEUTICS INC 1.75%
SPYRE THERAPEUTICS INC 1.67%
IOVANCE BIOTHERAPEUTICS INC 1.62%
ORUKA THERAPEUTICS INC 1.53%
TG THERAPEUTICS INC 1.51%
GRAIL INC 1.46%
ALKERMES PLC 1.43%
Check overlap with more funds →

Side by side

SCHX Schwab U.S. Large-Cap ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks an index of U.S. Large-Cap Biotech
Total return, 1 year +13.1% +41.2%
Its benchmark over the same days +13.7% (IVV) not measured
Gap to its benchmark −0.6 pts vs IVV not measured
Expense ratio 0.03% 0.35%
Already in the S&P 500 93.6% 13.2%
Holdings 747 165
Net assets, SCHX as of Aug 31, 2026 and XBI as of Oct 27, 2026 $74.2bn $10.3bn

SCHX and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
SCHX

SCHX tracks an index of U.S. Large-Cap. Over the year to Oct 28, 2026 it returned +13.1% with distributions reinvested, against +13.7% for its benchmark, the S&P 500 Index. The prospectus expense ratio is 0.03% a year. By its holdings filed for Aug 31, 2026, 94% of the fund by weight is stocks the S&P 500 also holds, across 747 positions, with the top ten at 36.0%.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are SCHX and XBI in the same category?
SCHX is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, SCHX or XBI?
In the year to Oct 28, 2026, with distributions reinvested, SCHX returned +13.1% and XBI +41.2%.
Which is cheaper, SCHX or XBI?
SCHX is cheaper, by 0.32 percentage points a year. That is about $32 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do SCHX and XBI overlap with the S&P 500?
By their latest filed holdings, 94% of SCHX and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, SCHX against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/schx-vs-xbi

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