Data as of Oct 28, 2026.

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VLUE vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, VLUE returned +54.7% to XBI's +41.2%, and VLUE charges 0.15% to XBI's 0.35%.

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Net assets: $9.4bn on Oct 28, 2026 for iShares MSCI USA Value Factor ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+54.7%
VLUE total return, 1 year
+41.2%
XBI total return, 1 year
0.15%
VLUE expense ratio
0.35%
XBI expense ratio

Pair scorecard

VLUE costs 0.20 points a year less; their one-year returns differ by 13.5 points; XBI is 1.1 times larger.

VLUE vs XBI: Differences, Returns & Fees
MeasureVLUEXBI
Return
Total return, 1 year+54.7%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksMSCI USA Enhanced Value IndexBiotech
Cost and size
Expense ratio0.15%0.35%
Net assets, as of Oct 27, 2026$9.3bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common1%
Top ten holdings, share of the fund42.8%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, VLUE and XBI hold 1% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first VLUE XBI
BIOGEN 0.40% 1.75%
UNITED THERAPEUTICS 0.17% 1.71%
Only in one fund ↓
Only in VLUE
MICRON TECHNOLOGY 20.94%
CISCO SYSTEMS INC 4.37%
GENERAL MOTORS 3.54%
VERIZON COMMUNICATIONS INC 2.72%
AT&T 2.24%
HEWLETT PACKARD ENTERPRISE 1.95%
PFIZER 1.86%
BANK OF AMERICA 1.77%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
HALOZYME THERAPEUTICS INC 1.75%
AMGEN INC 1.68%
ABBVIE INC 1.67%
SPYRE THERAPEUTICS INC 1.67%
EXELIXIS INC 1.64%
Check overlap with more funds →

Side by side

VLUE iShares MSCI USA Value Factor ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks the MSCI USA Value Factor Biotech
Total return, 1 year +54.7% +41.2%
Its benchmark over the same days +13.6% (MLRG) not measured
Gap to its benchmark +41.1 pts vs MLRG not measured
Expense ratio 0.15% 0.35%
Already in the S&P 500 96.6% 13.2%
Holdings 148 165
Net assets, VLUE as of Oct 28, 2026 and XBI as of Oct 27, 2026 $9.4bn $10.3bn

VLUE and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
VLUE

VLUE tracks the MSCI USA Value Factor. Over the year to Oct 28, 2026 it returned +54.7% with distributions reinvested, against +13.6% for its benchmark, the MSCI USA Index. The prospectus expense ratio is 0.15% a year. By its holdings published by its issuer for Oct 27, 2026, 97% of the fund by weight is stocks the S&P 500 also holds, across 148 positions, with the top ten at 42.8%.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are VLUE and XBI in the same category?
VLUE is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, VLUE or XBI?
In the year to Oct 28, 2026, with distributions reinvested, VLUE returned +54.7% and XBI +41.2%.
Which is cheaper, VLUE or XBI?
VLUE is cheaper, by 0.20 percentage points a year. That is about $20 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do VLUE and XBI overlap with the S&P 500?
By their latest filed holdings, 97% of VLUE and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, VLUE against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/vlue-vs-xbi

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