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Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

SPHQ vs XBI: how they differ

SPHQ and XBI hold 0% of their weight in the same names, and XBI returned more over the year.

Invesco S&P 500 Quality ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.

What they hold in common

By the books each fund has filed, SPHQ and XBI hold 0% of their money in the same securities at the same weight.

Positions SPHQ and XBI both hold, largest shared weight first
HoldingSPHQXBI
Incyte Corp0.17%1.13%
Largest positions each one holds and the other does not
Only in SPHQOnly in XBI
Mastercard Inc 5.78%MODERNA INC 2.87%
Visa Inc 5.68%TWIST BIOSCIENCE CORP 1.81%
Apple Inc 5.60%HALOZYME THERAPEUTICS INC 1.47%
Lam Research Corp 4.10%NATERA INC 1.46%
Netflix Inc 4.00%KYMERA THERAPEUTICS INC 1.45%
GE Vernova Inc 3.92%TRAVERE THERAPEUTICS INC 1.40%
Costco Wholesale Corp 3.85%ROIVANT SCIENCES LTD 1.39%
General Electric Co 3.62%ORUKA THERAPEUTICS INC 1.38%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 10, 2026.

SPHQ and XBI on the fields both publish, as of Sep 13, 2026. Source: ETFIQ.
SPHQ
Invesco S&P 500 Quality ETF
XBI
State Street(R) SPDR(R) S&P(R) Biotech ETF
Where it sitsCore index fundCore index fund
IssuerInvescoState Street
What it isS&P 500 QualitySPDR S&P Biotech
Total return, 1 year+17.4%+64.0%
S&P 500 over the same days+17.5%+17.5%
Gap to the S&P 500−0.1 pts+46.5 pts
Expense ratio0.15%0.35%
Already in the S&P 50099.9%8.5%
Holdings100154

SPHQ in plain words

SPHQ is an index equity fund tracking the S&P 500 Quality. Over the year to Sep 11, 2026 it returned +17.4% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.15% a year. By its holdings filed for Sep 10, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 100 positions, with the top ten at 43.4%. It sat 6.1% below its high of Jun 30, 2026 on Sep 11, 2026.

XBI in plain words

XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Sep 10, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 15.9%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.

Questions people ask

Which returned more over the last year, SPHQ or XBI?
In the year to Sep 13, 2026, with distributions reinvested, SPHQ returned +17.4% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
Which is cheaper, SPHQ or XBI?
SPHQ charges 0.15% a year and XBI charges 0.35%, so SPHQ is cheaper. Fees come from each fund's prospectus.
How much do SPHQ and XBI overlap with the S&P 500?
By their latest filed holdings, 100% of SPHQ and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

SPHQ against XBI, ETFIQ, data as of Sep 13, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, SPHQ against XBI, data as of Sep 13, 2026. https://etfiq.com/compare/any/sphq-vs-xbi Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources