Data as of Oct 28, 2026.

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Across categories

IBB vs SPHQ: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to SPHQ's +14.1%, and SPHQ charges 0.15% to IBB's 0.44%.

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Net assets on Oct 27, 2026: $11.0bn for iShares Biotechnology ETF and $18.7bn for Invesco S&P 500 Quality ETF.

At a glance
+37.5%
IBB total return, 1 year
+14.1%
SPHQ total return, 1 year
0.44%
IBB expense ratio
0.15%
SPHQ expense ratio

Pair scorecard

SPHQ costs 0.29 points a year less; their one-year returns differ by 23.4 points; SPHQ is 1.7 times larger.

IBB vs SPHQ: Differences, Returns & Fees
MeasureIBBSPHQ
Return
Total return, 1 year+37.5%+14.1%
Drawdown
Below its high6.4%, high on Jun 30, 2026
Benchmark
What it tracksBiotechS&P 500 Quality Index
Cost and size
Expense ratio0.44%0.15%
Net assets, as of Oct 27, 2026$11.0bn$18.7bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%43.3%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

Dec 16, 2005 to Oct 23, 2026 · 1,088 weekly returns
IBB SPHQ
Return
Total return edge IBB +748.5% +599.2%
Annualized edge IBB (slight) +10.8% +9.7%
Price return edge IBB +712.2% +432.7%
Risk
Volatility edge SPHQ 22.6% 18.0%
Max drawdown edge IBB −37.5% −56.9%
Risk-adjusted
Sharpe edge SPHQ (slight) 0.49 0.51
Sortino edge Tie 0.70 0.70
Calmar edge IBB 0.29 0.17
Reading

IBB returned more: +748.5% to +599.2%. SPHQ swung less: 18.0% to 22.6%. IBB fell less at its worst: −37.5% to −56.9%.

Full scorecard

9 measures, with how each is measured
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Risk and return: IBB vs SPHQ: Differences, Returns & Fees
MeasureIBBSPHQEdgeHow it is measured
Return
Total return+748.5%+599.2%IBBPrice change plus distributions, reinvested.
Annualized+10.8%+9.7%IBB (slight)Total return as a yearly rate.
Price return+712.2%+432.7%IBBPrice change alone, distributions left out.
Risk
Volatility22.6%18.0%SPHQSpread of weekly returns, annualized. Lower is steadier.
Downside deviation15.8%13.0%SPHQLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.5%−56.9%IBBDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.490.51SPHQ (slight)Return above Treasury bills per unit of volatility.
Sortino0.700.70TieReturn above Treasury bills per unit of downside deviation.
Calmar0.290.17IBBAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,088 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

0%

By the books each fund has filed, IBB and SPHQ hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB SPHQ
INCYTE CORP 1.63% 0.17%
BIO TECHNE 0.79% 0.11%
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in SPHQ
Mastercard Inc 6.25%
Visa Inc 6.23%
Apple Inc 5.96%
Costco Wholesale Corp 4.24%
GE Vernova Inc 3.81%
Cisco Systems Inc 3.65%
General Electric Co 3.33%
Lam Research Corp 3.32%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF SPHQ Invesco S&P 500 Quality ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the S&P 500 Quality
Total return, 1 year +37.5% +14.1%
Its benchmark over the same days not measured +13.7% (IVV)
Gap to its benchmark not measured +0.4 pts vs IVV
Expense ratio 0.44% 0.15%
Already in the S&P 500 40.2% 100.0%
Holdings 245 102
Net assets, as of Oct 27, 2026 $11.0bn $18.7bn

IBB and SPHQ on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-972C4AA88A

IBB and SPHQ do different jobs. What does each one do in a portfolio?

  1. What each follows. IBB follows Biotech and SPHQ follows S&P 500 Quality Index.
  2. Holdings in common. 0% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 IBB returned +37.5% and SPHQ +14.1% with distributions reinvested, a gap of 23.4 points.

Data as of Oct 28, 2026.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

SPHQ

SPHQ tracks the S&P 500 Quality. Over the year to Oct 28, 2026 it returned +14.1% with distributions reinvested, against +13.7% for its benchmark, the S&P 500 Index. The prospectus expense ratio is 0.15% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 102 positions, with the top ten at 43.3%. It sat 6.4% below its high of Jun 30, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and SPHQ in the same category?
IBB is a thematic ETF and SPHQ is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or SPHQ?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and SPHQ +14.1%.
Which is cheaper, IBB or SPHQ?
SPHQ is cheaper, by 0.29 percentage points a year. That is about $29 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and SPHQ overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 100% of SPHQ by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against SPHQ, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-sphq

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