Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.
IBB vs SPHQ: how they differ
IBB and SPHQ hold 0% of their weight in the same names, and IBB returned more over the year.
iShares Biotechnology ETF and Invesco S&P 500 Quality ETF.
What they hold in common
By the books each fund has filed, IBB and SPHQ hold 0% of their money in the same securities at the same weight.
| Only in IBB | Only in SPHQ |
|---|---|
| VERTEX PHARMACEUTICALS 7.94% | Mastercard Inc 5.78% |
| AMGEN INC 7.85% | Visa Inc 5.68% |
| GILEAD SCIENCES 7.44% | Apple Inc 5.60% |
| REGENERON PHARMACEUTICALS 5.92% | Lam Research Corp 4.10% |
| ARGENX SE ADR 3.78% | Netflix Inc 4.00% |
| MODERNA 3.67% | GE Vernova Inc 3.92% |
| NATERA 3.30% | Costco Wholesale Corp 3.85% |
| REVOLUTION MEDICINES 2.87% | General Electric Co 3.62% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 10, 2026.
| IBB iShares Biotechnology ETF | SPHQ Invesco S&P 500 Quality ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | iShares | Invesco |
| What it is | Biotechnology | S&P 500 Quality |
| Total return, 1 year | +41.5% | +17.4% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | +24.0 pts | −0.1 pts |
| Expense ratio | 0.44% | 0.15% |
| Already in the S&P 500 | 35.6% | 99.9% |
| Holdings | 233 | 100 |
IBB in plain words
IBB is an index equity fund tracking the Biotechnology. Over the year to Sep 11, 2026 it returned +41.5% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.44% a year. By its holdings filed for Sep 10, 2026, 36% of the fund by weight is stocks the S&P 500 also holds, across 233 positions, with the top ten at 47.5%. It sat 6.5% below its high of Aug 19, 2026 on Sep 11, 2026.
SPHQ in plain words
SPHQ is an index equity fund tracking the S&P 500 Quality. Over the year to Sep 11, 2026 it returned +17.4% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.15% a year. By its holdings filed for Sep 10, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 100 positions, with the top ten at 43.4%. It sat 6.1% below its high of Jun 30, 2026 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, IBB or SPHQ?
- In the year to Sep 13, 2026, with distributions reinvested, IBB returned +41.5% and SPHQ returned +17.4%, so IBB returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, IBB or SPHQ?
- IBB charges 0.44% a year and SPHQ charges 0.15%, so SPHQ is cheaper. Fees come from each fund's prospectus.
- How much do IBB and SPHQ overlap with the S&P 500?
- By their latest filed holdings, 36% of IBB and 100% of SPHQ by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.
Other comparisons
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBB against SPHQ, data as of Sep 13, 2026. https://etfiq.com/compare/any/ibb-vs-sphq Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources