Do SOXX and XBI hold the same stocks?

By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, SOXX or XBI?

SOXX has 74% of its weight in S&P 500 names and XBI has 13%, so XBI differs more from the index.

Which is cheaper, SOXX or XBI?

SOXX charges 0.33% a year and XBI charges 0.35%, so SOXX is cheaper. Fees come from each fund's prospectus.

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SOXX vs XBI: which is really different?

SOXX and XBI hold 0% of their weight in the same names, and SOXX returned +93.4% over the year. iShares Semiconductor ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.

SOXX costs 0.02 points a year less; their one-year returns differ by 48.4 points; SOXX is 4.6 times larger.

	SOXX	XBI
Expense ratio	0.33%	0.35%
Net assets, SOXX as of Oct 9, 2026 and XBI as of Oct 8, 2026	$45.9bn	$9.9bn
Total return, 1 year	+93.4%	+45.0%
What it tracks	Semiconductors	Biotech
Holdings in common	0%
S&P 500, total return, 1 year	+17.3%
Against the S&P 500, 1 year	ahead by 76.1 pts	ahead by 27.7 pts
Below its all-time high	14.5%, high on Jun 22, 2026	11.1%, high on Feb 8, 2021

Holdings in common uses holdings dated Oct 8, 2026.

73.5%

SOXX in the S&P 500

12.7%

XBI in the S&P 500

+93.4%

SOXX total return, 1 year

+45.0%

XBI total return, 1 year

SOXX · 1 year to Oct 9, 202627% of its weight is outside the S&P 500

74% of SOXX's weight is in S&P 500 companies and 27% is outside the index. Holdings as of Oct 8, 2026.

XBI · 1 year to Oct 9, 202687% of its weight is outside the S&P 500

13% of XBI's weight is in S&P 500 companies and 87% is outside the index. Holdings as of Oct 8, 2026.

ETFIQ Off-Index Score · XBI scores higherHow much of it is not the index it is sold as an alternative to?

SOXX 13.2

XBI 55.2

0.1, the lowest in this set92.3, the highest

A percentile among the 391 thematic ETFs with a holdings filing. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, SOXX and XBI hold 0% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Oct 8, 2026.

50%

half

0% in common

Positions both hold, largest shared weight first

Holding SOXX XBI

Only in SOXX

ADVANCED MICRO DEVICES 9.50%

INTEL CORPORATION 8.62%

MICRON TECHNOLOGY 7.78%

NVIDIA 7.52%

BROADCOM INC 7.01%

MARVELL TECHNOLOGY 4.67%

ANALOG DEVICES 4.04%

KLA 4.04%

Only in XBI

MODERNA INC 2.20%

TWIST BIOSCIENCE CORP 1.84%

NATERA INC 1.79%

ABBVIE INC 1.65%

UNITED THERAPEUTICS CORP 1.59%

AMGEN INC 1.58%

BIOGEN INC 1.57%

HALOZYME THERAPEUTICS INC 1.55%

0% of the two portfolios are the same securities at the same weight.

Performance, window by window

	Total return		vs the S&P 500		vs the Nasdaq-100
Window	SOXX	XBI	SOXX	XBI	SOXX	XBI
3 months	−3.7%	−3.3%	−7.1 pts	−6.7 pts	−7.4 pts	−7.0 pts
6 months	+44.9%	+18.9%	+29.7 pts	+3.8 pts	+21.7 pts	−4.3 pts
1 year	+93.4%	+45.0%	+76.1 pts	+27.7 pts	+69.8 pts	+21.4 pts
3 years	+251.9%	+114.6%	+166.1 pts	+28.8 pts	+144.6 pts	+7.3 pts
Since launch SOXX Jul 2001 · XBI Feb 2006	+2,733.5%	+890.7%	+1,830.1 pts	+92.2 pts	+767.8 pts	−1,164.7 pts

Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

SOXX

iShares Semiconductor ETF · Holds 31 stocks in semiconductors, 74% of its weight in S&P 500 companies

XBI

State Street(R) SPDR(R) S&P(R) Biotech ETF · Holds 165 stocks in biotech, 13% of its weight in S&P 500 companies

Issuer iShares State Street

Theme Semiconductors Biotech

In the S&P 500 73.5% 12.7%

Active share vs the S&P 500 82.3% 98.4%

In the Nasdaq-100 66.0% 8.5%

Holdings 31 165

Top ten, share of the fund 61.2% 16.9%

Expense ratio 0.33% 0.35%

Fee for the differing part 0.40% 0.36%

Total return, 1 year +93.4% +45.0%

vs the S&P 500 +76.1 pts +27.7 pts

vs the Nasdaq-100 +69.8 pts +21.4 pts

Below its high −14.5% −11.1%

Net assets, SOXX as of Oct 9, 2026 and XBI as of Oct 8, 2026 $45.9bn $9.9bn

As of Oct 9, 2026. Source: ETFIQ.

SOXX in plain words

By weight, 74% of SOXX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 82%. The top ten holdings are 61% of the fund across 31 positions, as published by its issuer for Oct 8, 2026. Over the year to Oct 9, 2026 the fund returned +93.4% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 76.1 pts. It sits 14.5% below its all-time high of Jun 22, 2026.

XBI in plain words

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 17% of the fund across 165 positions, as published by its issuer for Oct 8, 2026. Over the year to Oct 9, 2026 the fund returned +45.0% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 27.7 pts. It sits 11.1% below its all-time high of Feb 8, 2021.

Questions people ask

Do SOXX and XBI hold the same stocks?: By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, SOXX or XBI?: SOXX has 74% of its weight in S&P 500 names and XBI has 13%, so XBI differs more from the index.
Which is cheaper, SOXX or XBI?: SOXX charges 0.33% a year and XBI charges 0.35%, so SOXX is cheaper. Fees come from each fund's prospectus.

Other comparisons

SOXX vs IBB SOXX vs DRAM SOXX vs AIQ SOXX vs AIRR XBI vs SMH XBI vs AIQ XBI vs GDXJ XBI vs COPX

SOXX on its own →XBI on its own →How every figure is computed →Standards and sources →

Where these figures came from

SOXX filings on SEC EDGAR ↗SOXX prospectus with the expense ratio (SEC) ↗iShares page for SOXX ↗XBI filings on SEC EDGAR ↗XBI prospectus with the expense ratio (SEC) ↗State Street website ↗

ETFIQ links to the documents behind every figure; a link is not an endorsement. A comparison is not a recommendation.

How this is computed

It is a position in a set, not a rating, and neither end of it is a recommendation.

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

Every figure is an ETFIQ calculation with distributions reinvested.

Cite this page

ETFIQ, SOXX against XBI, data as of Oct 9, 2026. https://etfiq.com/compare/themes/soxx-vs-xbi

Open data

Free to use with attribution for figures ETFIQ computes; issuer data stays under its owner's terms.