Data as of Oct 28, 2026.

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AVLV vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, AVLV returned +29.6% to XBI's +41.2%, and AVLV charges 0.15% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $22.4bn for Avantis U.S. Large Cap Value ETF and $10.3bn for State Street SPDR S&P Biotech ETF.

At a glance
+29.6%
AVLV total return, 1 year
+41.2%
XBI total return, 1 year
0.15%
AVLV expense ratio
0.35%
XBI expense ratio

Pair scorecard

AVLV costs 0.20 points a year less; their one-year returns differ by 11.6 points; AVLV is 2.2 times larger.

AVLV vs XBI: Differences, Returns & Fees
MeasureAVLVXBI
Return
Total return, 1 year+29.6%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksNo index, actively managedBiotech
Cost and size
Expense ratio0.15%0.35%
Net assets, as of Oct 27, 2026$22.4bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund26.8%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, AVLV and XBI hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first AVLV XBI
EXELIXIS INC COMMON STOCK USD.001 0.35% 1.64%
INCYTE CORP COMMON STOCK USD.001 0.02% 1.35%
Only in one fund ↓
Only in AVLV
MICROSOFT CORP COMMON STOCK USD.00000625 3.48%
MICRON TECHNOLOGY INC COMMON STOCK USD.1 2.96%
AMAZON.COM INC COMMON STOCK USD.01 2.92%
META PLATFORMS INC CLASS A COMMON STOCK USD.000006 2.91%
APPLE INC COMMON STOCK USD.00001 2.85%
JPMORGAN CHASE + CO COMMON STOCK USD1.0 2.66%
EXXONMOBIL HOLDINGS CORP COMMON STOCK 2.56%
ELI LILLY + CO COMMON STOCK 2.51%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
Check overlap with more funds →

Side by side

AVLV Avantis U.S. Large Cap Value ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Actively managed Biotech
Total return, 1 year +29.6% +41.2%
Its benchmark over the same days +27.5% (IWD) not measured
Gap to its benchmark +2.1 pts vs IWD not measured
Expense ratio 0.15% 0.35%
Already in the S&P 500 84.3% 13.2%
Holdings 298 165
Net assets, as of Oct 27, 2026 $22.4bn $10.3bn

AVLV and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
AVLV

Over the year to Oct 28, 2026 it returned +29.6% with distributions reinvested, against +27.5% for its benchmark, the Russell 1000 Value.

AVLV is actively managed and tracks no index. The prospectus expense ratio is 0.15% a year. By its holdings published by its issuer for Oct 27, 2026, 84% of the fund by weight is stocks the S&P 500 also holds, across 298 positions, with the top ten at 26.8%.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are AVLV and XBI in the same category?
AVLV is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, AVLV or XBI?
In the year to Oct 28, 2026, with distributions reinvested, AVLV returned +29.6% and XBI +41.2%.
Which is cheaper, AVLV or XBI?
AVLV is cheaper, by 0.20 percentage points a year. That is about $20 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do AVLV and XBI overlap with the S&P 500?
By their latest filed holdings, 84% of AVLV and 13% of XBI by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, AVLV against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/avlv-vs-xbi

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