Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.
BITO vs XBI: how they differ
BITO and XBI hold 0% of their weight in the same names, and XBI returned more over the year.
ProShares Bitcoin ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, BITO and XBI hold 0% of their money in the same securities at the same weight.
| Only in BITO | Only in XBI |
|---|---|
| CME BITCOIN FUT DIGITAL ASSETS 25/SEP/20 81.49% | MODERNA INC 2.87% |
| COINBASE BIT FUT DIGITAL ASSETS 25/SEP/2 14.27% | TWIST BIOSCIENCE CORP 1.81% |
| S&P CME BITCOIN FUTURES DAILY ROLL INDEX 4.24% | HALOZYME THERAPEUTICS INC 1.47% |
| NATERA INC 1.46% | |
| KYMERA THERAPEUTICS INC 1.45% | |
| TRAVERE THERAPEUTICS INC 1.40% | |
| ROIVANT SCIENCES LTD 1.39% | |
| ORUKA THERAPEUTICS INC 1.38% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 10, 2026 and Sep 11, 2026.
| BITO ProShares Bitcoin ETF | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | ProShares | State Street |
| What it is | Bitcoin | SPDR S&P Biotech |
| Total return, 1 year | −34.8% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | −52.3 pts | +46.5 pts |
| Expense ratio | 0.95% | 0.35% |
| Holdings | 3 | 154 |
BITO in plain words
BITO is a digital asset fund tracking the Bitcoin. Over the year to Sep 11, 2026 it returned −34.8% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.95% a year. It sat 40.3% below its high of Oct 6, 2025 on Sep 11, 2026.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Sep 10, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 15.9%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, BITO or XBI?
- In the year to Sep 13, 2026, with distributions reinvested, BITO returned −34.8% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, BITO or XBI?
- BITO charges 0.95% a year and XBI charges 0.35%, so XBI is cheaper. Fees come from each fund's prospectus.
Other comparisons
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, BITO against XBI, data as of Sep 13, 2026. https://etfiq.com/compare/any/bito-vs-xbi Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources