IBRN iShares Neuroscience and Healthcare ETF
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Over the year to Nov 4, 2026, IBRN returned 19.7%.
Promise check: Not measuredETFIQ has not yet listed which companies belong to the therapeutics and medical devices theme.
IBRN risk and return scorecard
vs ACWI, its stated benchmark (secondary) · Sep 2022 to Oct 2026 · 217 weekly returns · dividend-adjusted
Secondary: ACWI tracks the MSCI All Country World Index, named in its shareholder report. Its own benchmark is its holdings, which have no weekly prices.
Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records; risk-free rate: U.S. Treasury, Daily Treasury Bill Rates, 13-week coupon equivalent Method · Data
Money in and out
Net fund flows · Nov 3, 2026What you earned
What did you actually buy?
Therapeutics and medical devices · holdings as of Nov 3, 2026More on IBRN
Every number below is on this page. Open what you need.Price, 1 year
$33.97+2.2%1 day, priceClose, Nov 4, 2026
Price only. Total return over the same days, distributions reinvested, was +19.7%. Computed by ETFIQ from Tiingo daily prices.
Source: Tiingo end-of-day prices. Data as of Nov 4, 2026. Updated every trading night. Report a data error
Points (pts) are percentage points.
| Window | Total return | S&P 500 (SPY) |
|---|---|---|
| 1M Oct 5 – Nov 4, 2026 | +4.8% | −1.0% |
| 3M Aug 5 – Nov 4, 2026 | −10.7% | −0.1% |
| 6M May 6 – Nov 4, 2026 | −5.8% | +5.0% |
| YTD Dec 31, 2025 – Nov 4, 2026 | +5.1% | +13.3% |
| 1Y Nov 4, 2025 – Nov 4, 2026 | +19.7% | +14.8% |
| 3Y Nov 3, 2023 – Nov 4, 2026 | +65.0% | +82.9% |
| Since launch Aug 26, 2022 – Nov 4, 2026 | +40.3% | +100.1% |
| Since launch, annualised Aug 26, 2022 – Nov 4, 2026 | +8.4% | – |
Total returns, distributions reinvested.
Source: Tiingo end-of-day prices, with distributions reinvested.
Money in and out
Daily data · as of Nov 3, 2026IBRN: in the year to Nov 3, 2026, net $1.9m came in; in the month to Nov 3, 2026, nothing net moved.
Nov 3, 2026
Oct 28, 2026 to Nov 3, 2026
Oct 5, 2026 to Nov 3, 2026
Aug 4, 2026 to Nov 3, 2026
Jan 2, 2026 to Nov 3, 2026
Nov 4, 2025 to Nov 3, 2026
SEC filings, then daily counts
IBRN, net flow each trading day over the 65 sessions from Aug 4, 2026 to Nov 3, 2026: money came in on 1 day and went out on 0 days.
Money in on 1 of the 65 trading days, out on 0.
IBRN, net flow each trading day over the 251 sessions from Nov 4, 2025 to Nov 3, 2026: money came in on 1 day and went out on 0 days.
Money in on 1 of the 251 trading days, out on 0.
IBRN, net flow each trading day over the 400 sessions from Apr 2, 2025 to Nov 3, 2026: money came in on 1 day and went out on 0 days.
Money in on 1 of the 400 trading days, out on 0.
Computed by ETFIQ from iShares’s daily data: each day’s change in shares outstanding times the previous day’s net asset value.
How this is computed
Percentages are of net assets at the start of each window. Numbers are net: money in less money out. Checked against the filing: The month’s daily sum and the filing’s B.6 number agree within rounding or, where the filing’s is larger, within rounding plus the fund’s creation and redemption fees. The full rule is in the fund’s flows file. Every day and month ETFIQ holds for IBRN, back to Aug 2022, is in its flows file. Flows across every fund · How these flows are computed · Compare IBRN with other funds in the flows tool
Every trading day, last 3 months65 days
Most recent first.
Week by week, last year53 weeks
Net flow into IBRN each week, Nov 4, 2025 to Nov 3, 2026, most recent first, each week named by its last trading day with data. Computed by ETFIQ.
Month by month, money in and money outDec 2023 to Nov 2026
IBRN, money in and money out each month from Dec 2023 to Oct 2026: two bars a month, money in above the line and money out below. Bars for Dec 2023 to Jul 2026 are from IBRN’s SEC filings (N-PORT item B.6), and for Aug 2026 to Oct 2026 ETFIQ’s sums of its days. Nov 2026 is still in progress, so it is in the list and not drawn. Of the 36 months listed, money came in on net in 1 and went out in 1.
Bars for Dec 2023 to Jul 2026 are from IBRN’s SEC filings (N-PORT item B.6), and for Aug 2026 to Oct 2026 ETFIQ’s sums of its days. Of the 36 months listed, money came in on net in 1 and went out in 1.
Most recent first.
How this is computed
N-PORT months: money in is sales plus reinvestments; money out is redemptions. Months summed from daily data: money in adds the days money came in; money out adds the days it went out.
N-PORT months are the filed sales plus reinvestments less redemptions. Later months add up the daily data; the Source column names any missing day.
Source: ETFIQ, from the fund’s daily share counts and net asset values, and its SEC N-PORT filings. Data as of Nov 3, 2026.
IBRN key stats
Trading
as of Nov 4, 2026
IBRN for holders outside the US
IBRN top ten by weight, 43.7% of the fund, of its 70 equity positions, from the holdings published by its issuer for Nov 3, 2026. Source: the issuer’s own daily file.
Source: iShares’s daily holdings file. Updated each trading day. Last checked Nov 4, 2026.
About IBRN
How we measure
12 seats on IBRN, as of Nov 4, 2026: 1 Supports, 7 Challenges, 4 Not enough data.
Questions people ask about IBRN
- How much of IBRN is in S&P 500 companies?
- By its holdings published by its issuer for Nov 3, 2026, 5% of IBRN by weight is stocks the S&P 500 already holds. Its active share against the index is 100%, so that share is the part doing something different.
- What does IBRN hold?
- 70 positions as published by its issuer for Nov 3, 2026, with the top ten at 44% of the fund. The largest are BIOGEN at 5.4%, NEUROCRINE BIOSCIENCES at 5.1%, ALKERMES at 4.8%.
- Has IBRN beaten the S&P 500?
- Over the year to Nov 4, 2026 IBRN returned +19.7% with distributions reinvested, against +14.8% for the S&P 500, so it finished ahead of the index by 4.9 points.
- What does IBRN cost?
- The prospectus expense ratio is 0.47% a year. Because 100% of the fund differs from the S&P 500, the fee on that differing part works out at 0.47%.
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ETFIQ, IBRN, thematic ETFs, data as of Nov 4, 2026. https://etfiq.com/funds/ibrn
ETFIQ. (Nov 4, 2026). IBRN, thematic ETFs. Retrieved from https://etfiq.com/funds/ibrn
[IBRN, thematic ETFs (ETFIQ, Nov 4, 2026)](https://etfiq.com/funds/ibrn)
The difference bar for IBRN, redrawn every trading night.
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<figure style="margin:0;max-width:640px">
<iframe src="https://etfiq.com/embed/themes/ibrn/" title="IBRN: 5% of IBRN's weight is in S&P 500 companies and 95% is outside the index. Holdings as of Nov 3, 2026." width="640" height="346" loading="lazy" style="border:0;max-width:100%;width:100%"></iframe>
<figcaption style="font:13px/1.5 sans-serif">IBRN: 5% of IBRN's weight is in S&P 500 companies and 95% is outside the index. Holdings as of Nov 3, 2026. Data: <a href="https://etfiq.com/funds/ibrn">ETFIQ</a></figcaption>
</figure>The day's ETF flows, a comparison and one number. Every trading morning. About the Daily
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