Data as of Oct 27, 2026.
Therapeutics and medical devices ETFs
See every therapeutics and medical devices ETF by what it holds, not by its name. Funds that hold drug developers and medical device makers, usually in one field such as oncology, neuroscience or vaccines. 5 funds, largest first. Updated Oct 27, 2026. The typical fund carries 21% of its weight in S&P 500 stocks, the 34th most of the 53 themes with holdings on file.
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What these funds actually own
Between them the 5 funds' ten largest holdings name 45 companies, of which 5 appear in more than one.More
ALKERMES PLC is among the ten largest of 2 of them, at an average of 4.5% of the fund.
Therapeutics and medical devices ETFs, the companies their ten largest holdings name. The 15 most widely held of 45. Source: each fund's latest SEC filing or its issuer’s own daily holdings file, read by ETFIQ.
How this is counted
Each row counts the ten largest holdings of each fund, so a fund missing from a row may still hold that company lower down. Weights are of the funds that name it, not of the theme.
Share of each fund's weight in S&P 500 companies. Above half, the fund is mostly the S&P 500.
Dark line: the S&P 500 over the same days, +13.5%. Last column: the gap to each fund's own benchmark, in points.
The 5 largest therapeutics and medical devices ETFs
ETFIQ covers 5 therapeutics and medical devices ETFs. The largest are IHI ($3.6bn), CANC ($209m) and PSIL ($46m); fees run 0.37% to 1.00%, as of .
Every therapeutics and medical devices ETF, largest first
Click a column to sort| Ticker | Fund | Issuer | Net assets ↓ | In the S&P 500 | Active share | Total return 1Y | vs its benchmark 1Y | Fee |
|---|---|---|---|---|---|---|---|---|
| IHI | iShares U.S. Medical Devices ETF | iShares | $3.6bn | 88.4% | 98.7% | −12.2% | not measured | 0.37% |
| CANC | Tema Oncology ETF | Tema | $209m | 21.2% | 95.7% | +35.4% | not measured | 0.75% |
| PSIL | AdvisorShares Psychedelics ETF | AdvisorShares | $46m | 7.8% | 98.4% | +14.2% | not measured | 1.00% |
| IBRN | iShares Neuroscience and Healthcare ETF | iShares | $6.3m | 5.6% | 100.0% | +7.9% | not measured | 0.47% |
| MDEV | First Trust Indxx Medical Devices ETF | First Trust | $3.3m | 47.1% | 98.0% | +4.2% | not measured | 0.70% |
How much of each pair is the same fund
The closest pair is IHI and MDEV, which hold 32% of their weight in the same companies. The furthest apart is MDEV and PSIL at 0%. The middle pair of the 10 is 0%.
Therapeutics and medical devices ETFs, the share of each pair’s weight held in the same companies. Read across or down; the number is the same either way. Cells are shaded against the closest pair here, 32%. Source: each fund’s own filed or daily holdings, read by ETFIQ.
How to read the grid
Weight overlap adds the smaller of the two weights for every company both funds hold. Funds with a cut-short book are left out, not compared short.
What each fund holds alone
Therapeutics and medical devices ETFs, the largest holding no other fund in the grid holds. Source: ETFIQ.
Questions people ask
- How many therapeutics and medical devices ETFs are there?
- ETFIQ covers 5 US listed therapeutics and medical devices ETFs as of Oct 27, 2026. That is every one it can measure from the fund’s own published holdings.
- What is the largest therapeutics and medical devices ETF?
- IHI, iShares U.S. Medical Devices ETF, at $3.6bn in net assets as of Oct 26, 2026, the largest of the 5 therapeutics and medical devices ETFs with a published size.
- What is the cheapest therapeutics and medical devices ETF?
- IHI, iShares U.S. Medical Devices ETF, at 0.37% a year by its prospectus filed Jul 27, 2026, the lowest fee of the 5 therapeutics and medical devices ETFs that publish one.
- Which therapeutics and medical devices ETF has performed best over the past year?
- CANC, Tema Oncology ETF, at +35.4% total return over the year to Oct 27, 2026, the highest of the 5 therapeutics and medical devices ETFs with a full year of trading behind them. Past returns do not predict future ones.
- What do therapeutics and medical devices ETFs hold?
- Funds that hold drug developers and medical device makers, usually in one field such as oncology, neuroscience or vaccines. Between them the 5 therapeutics and medical devices ETFs ETFIQ can read name 45 companies in their ten largest holdings, by holdings dated Jun 30, 2026 to Oct 26, 2026, most widely ALKERMES PLC, which is among the ten largest of 2 of them.
- Do therapeutics and medical devices ETFs hold the same companies?
- It depends which two. Across the 10 pairs of the 5 therapeutics and medical devices ETFs with a full published book, by holdings dated Jun 30, 2026 to Oct 26, 2026, IHI and MDEV hold 32% of their weight in the same companies, MDEV and PSIL hold 0%, and the middle pair holds 0%. Two funds sold on one theme are not the same fund.
What the issuers say about this theme
About these links
The issuers behind these therapeutics and medical devices funds publish their own work on this theme. These are their pages and words, not ETFIQ’s. A fund company writing about a theme it sells is making a case.
Issuer material on this theme. Links leave ETFIQ. Source: each issuer’s own site.
Links are sources, not endorsements. Standards and sources →
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<figure style="margin:0;max-width:640px">
<a href="https://etfiq.com/themes/therapeutics"><img src="https://etfiq.com/assistant/api/embed/theme/therapeutics.svg" alt="Therapeutics and medical devices ETFs, one-year total return to Oct 27, 2026: CANC +35.4%, PSIL +14.2%, IBRN +7.9%, MDEV +4.2%, IHI −12.2%." width="640" style="max-width:100%;height:auto"></a>
<figcaption style="font:13px/1.5 sans-serif">Therapeutics and medical devices ETFs, one-year total return to Oct 27, 2026: CANC +35.4%, PSIL +14.2%, IBRN +7.9%, MDEV +4.2%, IHI −12.2%. Data: <a href="https://etfiq.com/themes/therapeutics">ETFIQ</a></figcaption>
</figure>Cite this pageCitation, APA and Markdown
ETFIQ, Therapeutics and medical devices ETFs, data as of Oct 27, 2026. https://etfiq.com/themes/therapeutics
ETFIQ. (Oct 27, 2026). Therapeutics and medical devices ETFs. Retrieved from https://etfiq.com/themes/therapeutics
[Therapeutics and medical devices ETFs (ETFIQ, Oct 27, 2026)](https://etfiq.com/themes/therapeutics)
Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data.