Data as of .
Therapeutics and medical devices ETFs
9 funds, measured by holdings rather than by name. The typical fund carries 21% of its weight in S&P 500 names, which is the 27th most of the 40 themes here with filed books.
What these funds actually own
Between them the 5 funds' ten largest holdings name 47 companies, of which 3 appear in more than one. ALKERMES PLC is among the ten largest of 2 of them, at an average of 4.4% of the fund.
| Company | Among the ten largest of | Average weight where it is | Largest, and in which fund |
|---|---|---|---|
| ALKERMES PLC ALKS | 2 of 5 | 4.4% | 4.5% in PSIL |
| NEUROCRINE BIOSCIENCES INC NBIX | 2 of 5 | 4.2% | 4.6% in PSIL |
| DEXCOM INC DXCM | 2 of 5 | 3.7% | 4.9% in IHI |
| ABBOTT LABORATORIES ABT | 1 of 5 | 18.8% | 18.8% in IHI |
| DEFINIUM THERAPEUTICS INC DFTX | 1 of 5 | 13.4% | 13.4% in PSIL |
| INTUITIVE SURGICAL ISRG | 1 of 5 | 13.3% | 13.3% in IHI |
| COMPASS PATHWAYS PLC CMPS | 1 of 5 | 11.9% | 11.9% in PSIL |
| ATAIBECKLEY INC ATAI | 1 of 5 | 10.9% | 10.9% in PSIL |
| STRYKER SYK | 1 of 5 | 9.7% | 9.7% in IHI |
| Revolution Medicines Inc RVMD | 1 of 5 | 7.8% | 7.8% in CANC |
| RELMADA THERAPEUTICS INC RLMD | 1 of 5 | 7.1% | 7.1% in PSIL |
| NRX PHARMACEUTICALS INC NRXP | 1 of 5 | 6.3% | 6.3% in PSIL |
| BECTON DICKINSON BDX | 1 of 5 | 5.2% | 5.2% in IHI |
| PRAXIS PRECISION MEDICINES PRAX | 1 of 5 | 5.2% | 5.2% in IBRN |
| DIANTHUS THERAPEUTICS INC DNTH | 1 of 5 | 5.0% | 5.0% in IBRN |
The 15 most widely held of 47. Each fund files its whole book and this counts the ten largest out of it, so a fund missing from a row may still hold that company below its own tenth position. Weights are of the funds that name it, never of the theme.
| Ticker | Fund | Issuer | In the S&P 500 | Active share | Total return 1Y | vs S&P 500 | Fee |
|---|---|---|---|---|---|---|---|
| IHI | iShares U.S. Medical Devices ETF | iShares | 87.5% | 98.7% | −17.3% | −34.8 pts | 0.37% |
| CANC | Tema Oncology ETF | Tema | 21.2% | 95.6% | +49.6% | +32.1 pts | 0.75% |
| PSIL | AdvisorShares Psychedelics ETF | AdvisorShares | 8.1% | 98.4% | +51.5% | +34.0 pts | 1.00% |
| IBRN | iShares Neuroscience and Healthcare ETF | iShares | 4.3% | 100.0% | +45.9% | +28.4 pts | 0.47% |
| MDEV | First Trust Indxx Medical Devices ETF | First Trust | 46.4% | 98.0% | −3.1% | −20.6 pts | 0.70% |
| CNCR | Range Cancer Therapeutics ETF | not established | no filing yet | no filing yet | listed 217 days | · | 0.79% |
| MNTL | Tema Neuroscience and Mental Health ETF | Tema | no filing yet | no filing yet | listed 217 days | · | 0.75% |
| MSGR | Direxion mRNA ETF | Direxion | no filing yet | no filing yet | 0.0% | −17.5 pts | not published |
| VIRS | Pacer BioThreat Strategy ETF | Pacer | no filing yet | no filing yet | listed 217 days | · | 0.70% |
Where to next
Where these figures came from
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ETFIQ is an independent publisher and makes no recommendations; every figure is stated arithmetic on published data. Standards and sources
Cite this page. ETFIQ, Therapeutics and medical devices ETFs, data as of Sep 11, 2026. https://etfiq.com/themes/therapeutics Free to use with attribution; the underlying files are at Open data.