The cheapest therapeutics and medical devices ETFs
See 5 funds ranked by the annual fee the fund charges. Updated Oct 20, 2026. A fee is one fact, not a verdict. Funds on one theme can hold different companies, and the holdings are on the theme page.
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| # | Ticker | Fund | Fee ↑ | Net assets | Weight in S&P 500 companies | Total return, 1Y |
|---|---|---|---|---|---|---|
| 1 | IHI | iShares U.S. Medical Devices ETF | 0.37% | $3.5bn | 88.5% | −10.1% |
| 2 | IBRN | iShares Neuroscience and Healthcare ETF | 0.47% | $6m | 5.3% | +9.3% |
| 3 | MDEV | First Trust Indxx Medical Devices ETF | 0.70% | $3m | 47.4% | +4.4% |
| 4 | CANC | Tema Oncology ETF | 0.75% | $204m | 21.9% | +36.5% |
| 5 | PSIL | AdvisorShares Psychedelics ETF | 1.00% | $46m | 7.8% | +7.0% |
Method
The 5 of 5 ETFs in the therapeutics and medical devices theme that publish an expense ratio, cheapest first. Across the funds listed here the annual fee runs from 0.4% to 1.0%.
The rest of the method
A fee is the one number a fund controls and the one a holder always pays. The list sorts one published figure, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.
ETFIQ links to the documents behind every figure; a link is not an endorsement. A ranking is not a recommendation or an opinion.
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ETFIQ, The cheapest therapeutics and medical devices ETFs, ranked by the annual fee the fund charges, data as of Oct 20, 2026. https://etfiq.com/rankings/themes-cheapest-therapeutics
ETFIQ. (Oct 20, 2026). The cheapest therapeutics and medical devices ETFs, ranked by the annual fee the fund charges. Retrieved from https://etfiq.com/rankings/themes-cheapest-therapeutics
[The cheapest therapeutics and medical devices ETFs, ranked by the annual fee the fund charges (ETFIQ, Oct 20, 2026)](https://etfiq.com/rankings/themes-cheapest-therapeutics)
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