Do IBRN and IHI hold the same stocks?

By their latest filings, 1% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, IBRN or IHI?

IBRN has 5% of its weight in S&P 500 names and IHI has 88%, so IBRN differs more from the index.

Which is cheaper, IBRN or IHI?

IBRN charges 0.47% a year and IHI charges 0.37%, so IHI is cheaper. Fees come from each fund's prospectus.

Share on X Download as PDF Open live

IBRN vs IHI: which is really different?

IBRN and IHI hold 1% of their weight in the same names, and IBRN returned +25.4% over the year. iShares Neuroscience and Healthcare ETF and iShares U.S. Medical Devices ETF.

4.7%

IBRN in the S&P 500

88.0%

IHI in the S&P 500

+25.4%

IBRN total return, 1 year

−14.4%

IHI total return, 1 year

IBRN · 1 year to Sep 30, 202695% of its weight is outside the S&P 500

5% of IBRN's weight is in S&P 500 companies and 95% is outside the index

IHI · 1 year to Sep 30, 202612% of its weight is outside the S&P 500

88% of IHI's weight is in S&P 500 companies and 12% is outside the index

ETFIQ Off-Index Score · IBRN scores higherHow much of it is not the index it is sold as an alternative to?

IBRN 92

IHI 57.6

0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, IBRN and IHI hold 1% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 30, 2026.

50%

half

1% in common

Positions both hold, largest shared weight first

Holding IBRN IHI

AXOGEN 3.22% 0.34%

INTEGRA LIFESCIENCES HOLDINGS 1.60% 0.15%

CERIBELL 0.91% 0.09%

USD CASH 0.02% 0.12%

BLK CSH FND TREASURY SL AGENCY 0.00% 0.01%

Only in IBRN

BIOGEN 4.74%

EDGEWISE THERAPEUTICS 4.36%

PTC THERAPEUTICS 4.33%

ARGENX SE ADR 4.31%

NEUROCRINE BIOSCIENCES 4.22%

ALKERMES 4.07%

SCHOLAR ROCK HOLDING 4.04%

PRAXIS PRECISION MEDICINES 3.83%

Only in IHI

ABBOTT LABORATORIES 17.77%

INTUITIVE SURGICAL 14.92%

MEDTRONIC PLC 11.47%

IDEXX LABORATORIES 4.58%

DEXCOM INC 4.55%

EDWARDS LIFESCIENCES 4.52%

STRYKER 4.51%

BECTON DICKINSON 4.49%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

1% of the two portfolios are the same securities at the same weight.

Performance, window by window

	Total return		vs the S&P 500		vs the Nasdaq-100
Window	IBRN	IHI	IBRN	IHI	IBRN	IHI
3 months	−13.2%	+2.5%	−15.7 pts	0.0 pts	−15.3 pts	+0.4 pts
6 months	−0.1%	−4.0%	−17.1 pts	−20.9 pts	−26.9 pts	−30.8 pts
1 year	+25.4%	−14.4%	+9.7 pts	−30.2 pts	+1.6 pts	−38.2 pts
3 years	+60.7%	+6.9%	−24.3 pts	−78.0 pts	−49.3 pts	−103.0 pts
Since launch IBRN Aug 2022 · IHI Jan 2010	+37.4%	+519.6%	−61.7 pts	−285.0 pts	−109.4 pts	−1217.9 pts

IBRN and IHI over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

IBRN

iShares Neuroscience and Healthcare ETF · Holds 80 stocks in therapeutics and medical devices, 5% of its weight in S&P 500 companies

IHI

iShares U.S. Medical Devices ETF · Holds 54 stocks in therapeutics and medical devices, 88% of its weight in S&P 500 companies

Issuer iShares iShares

Theme Therapeutics and medical devices Therapeutics and medical devices

In the S&P 500 4.7% 88.0%

Active share vs the S&P 500 100.0% 98.7%

In the Nasdaq-100 0.0% 28.2%

Holdings 80 54

Top ten, share of the fund 41.1% 75.7%

Expense ratio 0.47% 0.37%

Fee for the differing part 0.47% 0.37%

Total return, 1 year +25.4% −14.4%

vs the S&P 500 +9.7 pts −30.2 pts

vs the Nasdaq-100 +1.6 pts −38.2 pts

Below its high −18.2% −22.0%

Net assets $7m $3.4bn

IBRN and IHI on the same fields, as of Sep 30, 2026. Source: ETFIQ.

IBRN in plain words

By weight, 5% of IBRN's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 41% of the fund across 80 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned +25.4% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 9.7 pts. It sits 18.2% below its all-time high of Aug 19, 2026.

IHI in plain words

By weight, 88% of IHI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 76% of the fund across 54 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned −14.4% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 30.2 pts. It sits 22.0% below its all-time high of Sep 8, 2021.

Questions people ask

Do IBRN and IHI hold the same stocks?: By their latest filings, 1% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, IBRN or IHI?: IBRN has 5% of its weight in S&P 500 names and IHI has 88%, so IBRN differs more from the index.
Which is cheaper, IBRN or IHI?: IBRN charges 0.47% a year and IHI charges 0.37%, so IHI is cheaper. Fees come from each fund's prospectus.

Other comparisons

IBRN vs MDEV IBRN vs PSIL IBRN vs CANC IHI vs MDEV IHI vs PSIL IHI vs CANC

IBRN on its own →IHI on its own →How every figure is computed →Standards and sources →

Where these figures came from

IBRN and IHI filings on SEC EDGAR ↗IBRN prospectus with the expense ratio (SEC) ↗iShares page for IBRN ↗IHI prospectus with the expense ratio (SEC) ↗iShares page for IHI ↗

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement. A comparison is not a recommendation.

Cite this page

ETFIQ, IBRN against IHI, data as of Sep 30, 2026. https://etfiq.com/compare/themes/ibrn-vs-ihi

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.