OZEM Roundhill GLP-1 & Weight Loss ETF

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$29.75
+0.8% · 1 day, price
IQ’s readingComputed nightly from ETFIQ data. Not written live.

Over the year to Oct 28, 2026, OZEM returned 8.4%.

Holds 24 stocks in healthcare innovation and GLP-1, 30% of its weight in S&P 500 companiesRoundhill ↗Expense ratio 0.59%Fund assets $54m on Oct 28, 2026First traded May 21, 2024Benchmark Its own holdings, as of Oct 28, 2026; its prospectus names no index it tracksFund page at the issuer ↗SEC filings ↗Every Roundhill fund ETFIQ coversDividend history

Promise check: Not measuredIts theme exposure is measured once ETFIQ defines its theme company by company.

OZEM risk and return scorecard

vs its own holdings

Not measured: its benchmark is its own holdings, which has no weekly price series.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records; risk-free rate: U.S. Treasury, Daily Treasury Bill Rates, 13-week coupon equivalent Method · Data

Money in and out

Net fund flows · Oct 27, 2026
Latest day
$0
Last 5 trading days
−$1.2m
12 months to Jun 30, 2026
+$13.2m
In on 0 days, out on 1. 49 days missing.

What you earned

OZEM −3.7%: total return over one month to Oct 28, 2026.
OZEM−3.7%
OZEM −8.9%: total return over three months to Oct 28, 2026.
OZEM−8.9%
OZEM −0.6%: total return over six months to Oct 28, 2026.
OZEM−0.6%
OZEM −12.9%: total return over the year to Oct 28, 2026.
OZEM−12.9%
OZEM +8.4%: total return over one year to Oct 28, 2026.
OZEM+8.4%
OZEM +18.9%: total return since launch to Oct 28, 2026.
OZEM+18.9%

What did you actually buy?

Healthcare innovation and GLP-1 · holdings as of Oct 28, 2026
29.8%
Already in the S&P 500
97.8%
Active share vs the S&P 500
68.4%
Top ten holdings
+8.4%
Total return, 1 year
1.5%
12-month yield, capital gains included, on its starting price
$0.4099
Last payment, ex-date Dec 30, 2025
Share already in the S&P 500
29.8% of the fund by weight, holdings as of Oct 28, 2026.
Ten largest holdings
Eli Lilly & Co14.7%
Novo Nordisk A/S11.6%
Pfizer Inc8.2%
Kailera Therapeutics Inc6.3%
CSPC Pharmaceutical Group Ltd5.4%
Chugai Pharmaceutical Co Ltd5.1%
Amgen Inc4.9%
Viking Therapeutics Inc4.4%
AstraZeneca PLC4.1%
Roche Holding AG3.7%

More on OZEM

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Price, 1 year

$29.75+0.8%1 day, priceClose, Oct 28, 2026

Price only. Total return over the same days, distributions reinvested, was +8.4%. Computed by ETFIQ from Tiingo daily prices.

Source: Tiingo end-of-day prices. Data as of Oct 28, 2026. Updated every trading night. Report a data error

OZEM returns by window: total return, cash paid and price change
WindowTotal returnS&P 500 (SPY)
1M Sep 28 – Oct 28, 2026−3.7%+0.9%
3M Jul 29 – Oct 28, 2026−8.9%+6.1%
6M Apr 29 – Oct 28, 2026−0.6%+9.1%
YTD Dec 31, 2025 – Oct 28, 2026−12.9%+14.1%
1Y Oct 28, 2025 – Oct 28, 2026+8.4%+13.6%
Since launch May 21, 2024 – Oct 28, 2026+18.9%+49.6%
Since launch, annualised May 21, 2024 – Oct 28, 2026+7.4%–

Total returns, distributions reinvested. Listed May 2024: no 3 years windows.

Source: Tiingo end-of-day prices, with distributions reinvested.

Money in and out

Daily data · as of Oct 27, 2026

OZEM: in the 17 trading days to Oct 27, 2026, net $1.2m went out.

1D
$0
0.0% of $54.1m on Oct 26, 2026
Oct 27, 2026
5D
−$1.2m
−2.1% of $56.4m on Oct 20, 2026
Oct 21, 2026 to Oct 27, 2026
12 months
+$13.2m
39.8% of $33.2m on Jun 30, 2025
Jul 1, 2025 to Jun 30, 2026
monthly, from SEC filings
May 2024 to Jun 2026
+$48.4m
May 1, 2024 to Jun 30, 2026
monthly, from SEC filings
Net flow each trading day
Net flow into OZEM each trading day, Jul 28, 2026 to Oct 27, 2026−$1.2mmonthly, from SEC filingsdaily, from Roundhill+$1.2m−$1.2mJul 28, 2026Oct 27, 2026

OZEM, net flow each trading day over the 65 sessions from Jul 28, 2026 to Oct 27, 2026: money came in on 0 days and went out on 1 day, of the 16 days with daily data; the other 49 have none. Before Oct 6, 2026 ETFIQ has the fund’s monthly data only, from SEC filings: that span is shaded and draws no bars, and its months are in the month by month list.

In on 0 days, out on 1. 49 days missing.

Net flow into OZEM each trading day, Oct 28, 2025 to Oct 27, 2026−$1.2mmonthly, from SEC filingsdaily, from Roundhill+$1.2m−$1.2mOct 28, 2025Oct 27, 2026

OZEM, net flow each trading day over the 251 sessions from Oct 28, 2025 to Oct 27, 2026: money came in on 0 days and went out on 1 day, of the 16 days with daily data; the other 235 have none. Before Oct 6, 2026 ETFIQ has the fund’s monthly data only, from SEC filings: that span is shaded and draws no bars, and its months are in the month by month list.

In on 0 days, out on 1. 235 days missing.

Net flow into OZEM each trading day, Mar 26, 2025 to Oct 27, 2026−$1.2mmonthly, from SEC filingsdaily, from Roundhill+$1.2m−$1.2mMar 26, 2025Oct 27, 2026

OZEM, net flow each trading day over the 400 sessions from Mar 26, 2025 to Oct 27, 2026: money came in on 0 days and went out on 1 day, of the 16 days with daily data; the other 384 have none. Before Oct 6, 2026 ETFIQ has the fund’s monthly data only, from SEC filings: that span is shaded and draws no bars, and its months are in the month by month list.

In on 0 days, out on 1. 384 days missing.

Money in, netMoney out, netMonthly basis

Daily data starts Oct 6, 2026.

How this is computed

Computed by ETFIQ from Roundhill’s daily data: each day’s change in shares outstanding times the previous day’s net asset value. Percentages are of net assets at the start of each window. Numbers are net: money in less money out. Every day and month ETFIQ holds for OZEM, back to May 2024, is in its flows file. Flows across every fund · How these flows are computed · Compare OZEM with other funds in the flows tool

Every trading day, last 3 months16 days
Oct 27, 2026 $0
Oct 26, 2026 −$1.2m
Oct 23, 2026 $0
Oct 22, 2026 $0
Oct 21, 2026 $0
Oct 20, 2026 $0
Oct 19, 2026 $0
Oct 16, 2026 $0
Oct 15, 2026 $0
Oct 14, 2026 $0
Oct 13, 2026 $0
Oct 12, 2026 $0
Oct 9, 2026 $0
Oct 8, 2026 $0
Oct 7, 2026 $0
Oct 6, 2026 $0 covers 2 trading days

Most recent first.

Week by week, last year4 weeks
Oct 27, 2026 −$1.2m 2 days
Oct 23, 2026 $0
Oct 16, 2026 $0
Oct 9, 2026 $0 4 days

Net flow into OZEM each week, Oct 6, 2026 to Oct 27, 2026, most recent first, each week named by its last trading day with data. Computed by ETFIQ.

Month by month, money in and money outMay 2024 to Oct 2026

OZEM, money in and money out each month from May 2024 to Jun 2026: two bars a month, money in above the line and money out below. Every bar is from OZEM’s SEC filings (N-PORT item B.6). Oct 2026 is still in progress, so it is in the list and not drawn. Of the 27 months listed, money came in on net in 9 and went out in 10.

Every bar is from OZEM’s SEC filings (N-PORT item B.6). Of the 27 months listed, money came in on net in 9 and went out in 10.

MonthInOutNet
Oct 2026 ETFIQ, the sum of its days, Oct 6 to Oct 27$0−$1.2m−$1.2m
Jun 2026 SEC Form N-PORT+$2.8m$0+$2.8m
May 2026 SEC Form N-PORT$0−$2.5m−$2.5m
Apr 2026 SEC Form N-PORT$0$0$0
Mar 2026 SEC Form N-PORT+$2.9m−$3.0m−$101k
Feb 2026 SEC Form N-PORT$0$0$0
Jan 2026 SEC Form N-PORT+$13.2m$0+$13.2m
Dec 2025 SEC Form N-PORT+$666k−$3.7m−$3.0m
Nov 2025 SEC Form N-PORT+$5.6m$0+$5.6m
Oct 2025 SEC Form N-PORT$0−$1.1m−$1.1m
Sep 2025 SEC Form N-PORT$0−$1.6m−$1.6m
Aug 2025 SEC Form N-PORT$0$0$0
Jul 2025 SEC Form N-PORT$0$0$0
Jun 2025 SEC Form N-PORT$0−$3.5m−$3.5m
May 2025 SEC Form N-PORT$0$0$0
Apr 2025 SEC Form N-PORT+$3.6m−$6.2m−$2.6m
Mar 2025 SEC Form N-PORT$0$0$0
Feb 2025 SEC Form N-PORT$0−$1.5m−$1.5m
Jan 2025 SEC Form N-PORT$0$0$0
Dec 2024 SEC Form N-PORT+$1.3m−$1.3m+$10k
Nov 2024 SEC Form N-PORT+$2.6m−$5.9m−$3.3m
Oct 2024 SEC Form N-PORT+$6.3m−$3.4m+$2.8m
Sep 2024 SEC Form N-PORT$0$0$0
Aug 2024 SEC Form N-PORT+$5.4m−$2.0m+$3.4m
Jul 2024 SEC Form N-PORT+$10.3m−$2.3m+$8.1m
Jun 2024 SEC Form N-PORT+$23.1m−$1.3m+$21.8m
May 2024 SEC Form N-PORT+$9.9m$0+$9.9m

Most recent first.

How this is computed

N-PORT months: money in is sales plus reinvestments; money out is redemptions. Months summed from daily data: money in adds the days money came in; money out adds the days it went out.

N-PORT months are the filed sales plus reinvestments less redemptions. Later months add up the daily data; the Source column names any missing day.

Source: ETFIQ, from the fund’s daily share counts and net asset values, and its SEC N-PORT filings. Data as of Oct 27, 2026. Last checked Oct 29, 2026.

OZEM key stats

52-week high, daily closes to Oct 28, 2026 (ETFIQ)$37.01 on Jan 26, 2026
52-week low, daily closes to Oct 28, 2026 (ETFIQ)$27.64 on Oct 29, 2025
Close on Oct 28, 2026, within that range (ETFIQ)$29.75, 23% of the way from the low to the high
Holdings24
Top ten holdings weight68.4%
Range, beta and R-squared computed by ETFIQ from Tiingo daily prices.

Trading

as of Oct 28, 2026
Trading · OZEMas of Oct 28, 2026
·
Not scored1 of 6 measured · Oct 28, 2026
0 · Hard to tradeIQ Liquidity Score100 · Trades like a giant
Cost for your order · one way, half its 30-day median spread
Premium or discount to NAV, Oct 28 close+0.10%
−0.6%95% of days within ±0.48% · the 1% band is off this scale+0.6%
How to tradeSpread not read.
Full trading page: components, premium history, dealers →

OZEM top ten by weight, 68.4% of the fund, of its 24 equity positions, from the holdings published by its issuer for Oct 28, 2026. Source: the issuer’s own daily file.

Eli Lilly & Co LLY 14.67%
Novo Nordisk A/S NVO 11.62%
Pfizer Inc PFE 8.24%
Kailera Therapeutics Inc KLRA 6.30%
CSPC Pharmaceutical Group Ltd 1093 HKG 5.37%
Amgen Inc AMGN 4.86%
AstraZeneca PLC AZN 4.12%
Roche Holding AG ROP SWX 3.71%

Source: Roundhill’s daily holdings file. Updated each trading day. Last checked Oct 28, 2026.

About OZEM

Theme (ETFIQ, editorial)Healthcare innovation and GLP-1
First tradedMay 21, 2024
Already in the S&P 500, by weight (ETFIQ)29.8%
Outside the S&P 500, by weight (ETFIQ)70%
Active share vs the S&P 500 (ETFIQ)97.8%
Already in the Nasdaq-100, by weight (ETFIQ)6.9%
Active share vs the Nasdaq-100 (ETFIQ)98.5%
Top ten holdings weight68.4%
Holdings24
Holdings published for (the issuer’s daily file)Oct 28, 2026
Holdings as of the close of (the issuer’s daily file)Oct 28, 2026
Top holdingsEli Lilly & Co 14.7%, Novo Nordisk A/S 11.6%, Pfizer Inc 8.2%, Kailera Therapeutics Inc 6.3%, CSPC Pharmaceutical Group Ltd 5.4%, Chugai Pharmaceutical Co Ltd 5.1%, Amgen Inc 4.9%, Viking Therapeutics Inc 4.4%, AstraZeneca PLC 4.1%, Roche Holding AG 3.7%
Net assets (the issuer’s own daily fund list, as of Oct 28, 2026)$54mReport
Benchmark (ETFIQ, from its filings)Its own holdings, as of Oct 28, 2026; its prospectus names no index it tracks
Below its all-time high (ETFIQ)−19.6%
Expense ratio (485BPOS XBRL, Apr 30, 2026)0.59%Report
Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ)0.60%
Closest funds by holdings overlapTHNR 68%, PBPH 37%, YUNG 15%, GDOC 15%, AGNG 14%
Below its all-time high19.6%, high on Jan 26, 2026
How we measure
The top ten holdings are 68% of the fund across 24 positions, as published by its issuer for Oct 28, 2026. Over the year to Oct 28, 2026 the fund returned +8.4% with distributions reinvested. It sits 19.6% below its all-time high of Jan 26, 2026.
Holdings from the file the issuer publishes daily; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. Method
IQ Investment Committee on OZEM

12 seats on OZEM, as of Oct 28, 2026: 7 Challenges, 5 Not enough data.

In the tradition ofJohn BogleBogle-style Low CostChallenges
In the tradition ofBenjamin GrahamGraham-style Margin of SafetyNot enough data
In the tradition ofWarren Buffett & Charlie MungerBuffett & Munger-style QualityNot enough data
In the tradition ofPeter LynchLynch-style Growth at a Reasonable PriceNot enough data
In the tradition ofJohn TempletonTempleton-style Global ContrarianNot enough data
In the tradition ofRay DalioDalio-style All-WeatherChallenges
In the tradition ofHoward MarksMarks-style Cycles & RiskNot enough data
In the tradition ofStanley DruckenmillerDruckenmiller-style Macro & LiquidityChallenges
In the tradition ofDavid SwensenSwensen-style DiversificationChallenges
In the tradition ofCathie WoodWood-style Disruptive InnovationChallenges
In the tradition ofJesse LivermoreLivermore-style Trend FollowingChallenges
Uses ETFIQ’s measuresThe ETFIQ SkepticETFIQ’s own seatChallenges
Put OZEM to the committee →See all seats →No investor named is affiliated with or endorses ETFIQ. Not investment advice.

Questions people ask about OZEM

How much of OZEM is in S&P 500 companies?
By its holdings published by its issuer for Oct 28, 2026, 30% of OZEM by weight is stocks the S&P 500 already holds. Its active share against the index is 98%, so that share is the part doing something different.
What does OZEM hold?
24 positions as published by its issuer for Oct 28, 2026, with the top ten at 68% of the fund. The largest are Eli Lilly & Co at 14.7%, Novo Nordisk A/S at 11.6%, Pfizer Inc at 8.2%.
Has OZEM beaten the S&P 500?
Over the year to Oct 28, 2026 OZEM returned +8.4% with distributions reinvested, against +13.6% for the S&P 500, so it finished behind the index by 5.2 points.
What does OZEM cost?
The prospectus expense ratio is 0.59% a year. Because 98% of the fund differs from the S&P 500, the fee on that differing part works out at 0.60%.
Sources and dates
Prices, OZEM and S&P 500 (SPY)Tiingo end-of-day · Oct 28, 2026
Net assets, $54mThe issuer’s own daily fund list · Oct 28, 2026

Links are sources, not endorsements.

Cite this pageCitation, APA and Markdown

ETFIQ, OZEM, thematic ETFs, data as of Oct 28, 2026. https://etfiq.com/funds/ozem

The difference bar for OZEM, redrawn every trading night.

Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data.

How differently the money is placed, counting weights: one minus the sum of the smaller weight of each security across the fund and the index. 100% means nothing in common; 0% means the index itself. Two funds can hold the same names and still have a high active share if they weight them very differently.
Weight overlap
The share of money two portfolios hold in the same securities at the same weight.
Already in the index
The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at different weights.
The weight of the ten largest holdings. Above 50% the fund is a bet on a handful of companies, whatever the theme.
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OZEM: 30% of OZEM's weight is in S&P 500 companies and 70% is outside the index. Holdings as of Oct 28, 2026.
<figure style="margin:0;max-width:640px">
<a href="https://etfiq.com/funds/ozem"><img src="https://etfiq.com/assistant/api/embed/themes/ozem.svg" alt="OZEM: 30% of OZEM&#x27;s weight is in S&amp;P 500 companies and 70% is outside the index. Holdings as of Oct 28, 2026." width="640" style="max-width:100%;height:auto"></a>
<figcaption style="font:13px/1.5 sans-serif">OZEM: 30% of OZEM&#x27;s weight is in S&amp;P 500 companies and 70% is outside the index. Holdings as of Oct 28, 2026. Data: <a href="https://etfiq.com/funds/ozem">ETFIQ</a></figcaption>
</figure>

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