Do HEAL and OZEM hold the same stocks?

By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, HEAL or OZEM?

HEAL has 27% of its weight in S&P 500 names and OZEM has 27%, so HEAL differs more from the index.

Which is cheaper, HEAL or OZEM?

HEAL charges 0.50% a year and OZEM charges 0.59%, so HEAL is cheaper. Fees come from each fund's prospectus.

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HEAL vs OZEM: which is really different?

HEAL and OZEM hold 0% of their weight in the same names, and OZEM returned +14.0% over the year. Global X HealthTech ETF and Roundhill GLP-1 & Weight Loss ETF.

27.0%

HEAL in the S&P 500

26.6%

OZEM in the S&P 500

−7.4%

HEAL total return, 1 year

+14.0%

OZEM total return, 1 year

HEAL · 1 year to Sep 30, 202673% of its weight is outside the S&P 500

27% of HEAL's weight is in S&P 500 companies and 73% is outside the index

OZEM · 1 year to Sep 30, 202673% of its weight is outside the S&P 500

27% of OZEM's weight is in S&P 500 companies and 73% is outside the index

ETFIQ Off-Index Score · HEAL scores higherHow much of it is not the index it is sold as an alternative to?

HEAL 71.7

OZEM 46.9

0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, HEAL and OZEM hold 0% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 30, 2026.

50%

half

0% in common

Positions both hold, largest shared weight first

Holding HEAL OZEM

Only in HEAL

IQVIA HOLDINGS INC 6.14%

VEEVA SYSTEMS INC-CLASS A 6.00%

OSCAR HEALTH INC - CLASS A 5.65%

TEMPUS AI INC-CL A 5.37%

DEXCOM INC 5.07%

PRO MEDICUS LTD 4.18%

HIMS & HERS HEALTH INC 3.92%

RESMED INC 3.89%

Only in OZEM

Eli Lilly & Co 12.69%

Novo Nordisk A/S 11.09%

Pfizer Inc 7.69%

CSPC Pharmaceutical Group Ltd 6.52%

Viking Therapeutics Inc 5.47%

Kailera Therapeutics Inc 5.17%

Chugai Pharmaceutical Co Ltd 4.64%

Ascletis Pharma Inc 4.39%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

0% of the two portfolios are the same securities at the same weight.

Performance, window by window

	Total return		vs the S&P 500		vs the Nasdaq-100
Window	HEAL	OZEM	HEAL	OZEM	HEAL	OZEM
3 months	+3.3%	−4.9%	+0.8 pts	−7.5 pts	+1.2 pts	−7.1 pts
6 months	+23.4%	−3.5%	+6.4 pts	−20.5 pts	−3.5 pts	−30.4 pts
1 year	−7.4%	+14.0%	−23.1 pts	−1.7 pts	−31.2 pts	−9.8 pts
3 years	+7.5%	not published	−77.5 pts	not published	−102.5 pts	not published
Since launch HEAL Jul 2020 · OZEM May 2024	−36.6%	+23.1%	−192.9 pts	−24.7 pts	−230.4 pts	−41.3 pts

HEAL and OZEM over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

HEAL

Global X HealthTech ETF · Holds 43 stocks in healthcare innovation and GLP-1, 27% of its weight in S&P 500 companies

OZEM

Roundhill GLP-1 & Weight Loss ETF · Holds 26 stocks in healthcare innovation and GLP-1, 27% of its weight in S&P 500 companies

Issuer Global X Roundhill

Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1

In the S&P 500 27.0% 26.6%

Active share vs the S&P 500 99.6% 97.8%

In the Nasdaq-100 8.3% 6.2%

Holdings 43 26

Top ten, share of the fund 47.6% 66.4%

Expense ratio 0.50% 0.59%

Fee for the differing part 0.50% 0.60%

Total return, 1 year −7.4% +14.0%

vs the S&P 500 −23.1 pts −1.7 pts

vs the Nasdaq-100 −31.2 pts −9.8 pts

Below its high −56.4% −16.8%

Net assets $31m $58m

HEAL and OZEM on the same fields, as of Sep 30, 2026. Source: ETFIQ.

HEAL in plain words

By weight, 27% of HEAL's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 48% of the fund across 43 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned −7.4% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 23.1 pts. It sits 56.4% below its all-time high of Feb 12, 2021.

OZEM in plain words

By weight, 27% of OZEM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 66% of the fund across 26 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned +14.0% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 1.7 pts. It sits 16.8% below its all-time high of Jan 26, 2026.

Questions people ask

Do HEAL and OZEM hold the same stocks?: By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, HEAL or OZEM?: HEAL has 27% of its weight in S&P 500 names and OZEM has 27%, so HEAL differs more from the index.
Which is cheaper, HEAL or OZEM?: HEAL charges 0.50% a year and OZEM charges 0.59%, so HEAL is cheaper. Fees come from each fund's prospectus.

Other comparisons

HEAL vs HELX HEAL vs LGHT HEAL vs THNR HEAL vs WDNA OZEM vs THNR OZEM vs WDNA OZEM vs BMED OZEM vs HELX

HEAL on its own →OZEM on its own →How every figure is computed →Standards and sources →

Where these figures came from

HEAL filings on SEC EDGAR ↗HEAL prospectus with the expense ratio (SEC) ↗Global X page for HEAL ↗OZEM filings on SEC EDGAR ↗OZEM prospectus with the expense ratio (SEC) ↗Roundhill page for OZEM ↗

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement. A comparison is not a recommendation.

Cite this page

ETFIQ, HEAL against OZEM, data as of Sep 30, 2026. https://etfiq.com/compare/themes/heal-vs-ozem

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.