HEAL vs WDNA: which is really different?

HEAL and WDNA hold 2% of their weight in the same names, and WDNA returned +58.6% over the year. Global X HealthTech ETF and WisdomTree BioRevolution Fund.

27.0%
HEAL in the S&P 500
25.9%
WDNA in the S&P 500
−7.4%
HEAL total return, 1 year
+58.6%
WDNA total return, 1 year
HEAL · 1 year to Sep 30, 202673% of its weight is outside the S&P 500
73% of its weight is outside the S&P 50027% of HEAL's weight is in S&P 500 companies and 73% is outside the index27%73%in the S&P 500of its weight outside the S&P 500active share 100% · top ten 48% of the fund · 43 holdings filed Sep 30, 2026 · Nasdaq-100: 8% in73% of its weight is outside the S&P 50027% of HEAL's weight is in S&P 500 companies and 73% is outside the index27%73%inoutside the S&P 500active share 100% · top ten 48% of the fund

27% of HEAL's weight is in S&P 500 companies and 73% is outside the index

WDNA · 1 year to Sep 30, 202674% of its weight is outside the S&P 500
74% of its weight is outside the S&P 50026% of WDNA's weight is in S&P 500 companies and 74% is outside the index26%74%in the S&P 500of its weight outside the S&P 500active share 95% · top ten 31% of the fund · 80 holdings filed Jun 30, 2026 · Nasdaq-100: 6% in74% of its weight is outside the S&P 50026% of WDNA's weight is in S&P 500 companies and 74% is outside the index26%74%inoutside the S&P 500active share 95% · top ten 31% of the fund

26% of WDNA's weight is in S&P 500 companies and 74% is outside the index

ETFIQ Off-Index Score · HEAL scores higherHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, HEAL and WDNA hold 2% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and Sep 30, 2026.

half

2% in common

Positions both hold, largest shared weight first
Holding HEAL WDNA
TEMPUS AI INC-CL A 5.37% 2.29%
Only in HEAL
IQVIA HOLDINGS INC 6.14%
VEEVA SYSTEMS INC-CLASS A 6.00%
OSCAR HEALTH INC - CLASS A 5.65%
DEXCOM INC 5.07%
PRO MEDICUS LTD 4.18%
HIMS & HERS HEALTH INC 3.92%
RESMED INC 3.89%
GE HEALTHCARE TECHNOLOGY 3.86%
Only in WDNA
TWIST BIOSCIENCE CORP 5.96%
MODERNA INC 4.15%
ELI LILLY & COMPANY 4.08%
JOHNSON & JOHNSON 2.97%
UNITED THERAPEUTICS CORP 2.45%
NATERA INC 2.33%
IMMUNOME INC 2.26%
STRUCTURE THERAPEUTICS INC 2.12%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

2% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowHEALWDNAHEALWDNAHEALWDNA
3 months+3.3%+16.6%+0.8 pts+14.1 pts+1.2 pts+14.5 pts
6 months+23.4%+36.5%+6.4 pts+19.5 pts−3.5 pts+9.6 pts
1 year−7.4%+58.6%−23.1 pts+42.9 pts−31.2 pts+34.8 pts
3 years+7.5%+69.0%−77.5 pts−16.0 pts−102.5 pts−41.0 pts
Since launch
HEAL Jul 2020 · WDNA Jun 2021
−36.6%+2.8%−192.9 pts−93.2 pts−230.4 pts−128.7 pts

HEAL and WDNA over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

HEAL
Global X HealthTech ETF · Holds 43 stocks in healthcare innovation and GLP-1, 27% of its weight in S&P 500 companies
WDNA
WisdomTree BioRevolution Fund · Holds 80 stocks in healthcare innovation and GLP-1, 26% of its weight in S&P 500 companies
Issuer Global X WisdomTree
Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1
In the S&P 500 27.0% 25.9%
Active share vs the S&P 500 99.6% 95.3%
In the Nasdaq-100 8.3% 5.8%
Holdings 43 80
Top ten, share of the fund 47.6% 30.7%
Expense ratio 0.50% 0.45%
Fee for the differing part 0.50% 0.47%
Total return, 1 year −7.4% +58.6%
vs the S&P 500 −23.1 pts +42.9 pts
vs the Nasdaq-100 −31.2 pts +34.8 pts
Below its high −56.4% −8.1%
Net assets $31m $4m

HEAL and WDNA on the same fields, as of Sep 30, 2026. Source: ETFIQ.

HEAL in plain words

By weight, 27% of HEAL's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 48% of the fund across 43 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned −7.4% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 23.1 pts. It sits 56.4% below its all-time high of Feb 12, 2021.

WDNA in plain words

By weight, 26% of WDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 31% of the fund across 80 positions, as filed for Jun 30, 2026. Over the year to Sep 30, 2026 the fund returned +58.6% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 42.9 pts. It sits 8.1% below its all-time high of Sep 2, 2021.

Questions people ask

Do HEAL and WDNA hold the same stocks?
By their latest filings, 2% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, HEAL or WDNA?
HEAL has 27% of its weight in S&P 500 names and WDNA has 26%, so HEAL differs more from the index.
Which is cheaper, HEAL or WDNA?
HEAL charges 0.50% a year and WDNA charges 0.45%, so WDNA is cheaper. Fees come from each fund's prospectus.
Cite this page

ETFIQ, HEAL against WDNA, data as of Sep 30, 2026. https://etfiq.com/compare/themes/heal-vs-wdna

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.