Do HEAL and HELX hold the same stocks?

By their latest filings, 4% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, HEAL or HELX?

HEAL has 27% of its weight in S&P 500 names and HELX has 15%, so HEAL differs more from the index.

Which is cheaper, HEAL or HELX?

HEAL charges 0.50% a year and HELX charges 0.50%, so HEAL is cheaper. Fees come from each fund's prospectus.

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HEAL vs HELX: which is really different?

HEAL and HELX hold 4% of their weight in the same names, and HELX returned +44.5% over the year. Global X HealthTech ETF and Franklin Genomic Advancements ETF.

27.0%

HEAL in the S&P 500

15.1%

HELX in the S&P 500

−7.4%

HEAL total return, 1 year

+44.5%

HELX total return, 1 year

HEAL · 1 year to Sep 30, 202673% of its weight is outside the S&P 500

27% of HEAL's weight is in S&P 500 companies and 73% is outside the index

HELX · 1 year to Sep 30, 202685% of its weight is outside the S&P 500

15% of HELX's weight is in S&P 500 companies and 85% is outside the index

ETFIQ Off-Index Score · HEAL scores higherHow much of it is not the index it is sold as an alternative to?

HEAL 71.7

HELX 41.3

0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, HEAL and HELX hold 4% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and Sep 30, 2026.

50%

half

4% in common

Positions both hold, largest shared weight first

Holding HEAL HELX

TEMPUS AI INC-CL A 5.37% 1.97%

IQVIA HOLDINGS INC 6.14% 0.76%

HINGE HEALTH INC-A 2.71% 0.71%

RECURSION PHARMACEUTICALS-A 1.78% 0.07%

Only in HEAL

VEEVA SYSTEMS INC-CLASS A 6.00%

OSCAR HEALTH INC - CLASS A 5.65%

DEXCOM INC 5.07%

PRO MEDICUS LTD 4.18%

HIMS & HERS HEALTH INC 3.92%

RESMED INC 3.89%

GE HEALTHCARE TECHNOLOGY 3.86%

WAYSTAR HOLDING CORP 3.52%

Only in HELX

GUARDANT HEALTH INC 9.21%

NATERA INC 7.56%

KRYSTAL BIOTECH INC 6.41%

LIGAND PHARMACEUTICALS INC 4.68%

ADAPTIVE BIOTECHNOLOGIES CORP 4.04%

UNITED THERAPEUTICS CORP 3.55%

BRIDGEBIO PHARMA INC 3.54%

ELI LILLY & COMPANY 2.99%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

4% of the two portfolios are the same securities at the same weight.

Performance, window by window

	Total return		vs the S&P 500		vs the Nasdaq-100
Window	HEAL	HELX	HEAL	HELX	HEAL	HELX
3 months	+3.3%	+9.9%	+0.8 pts	+7.4 pts	+1.2 pts	+7.8 pts
6 months	+23.4%	+33.6%	+6.4 pts	+16.6 pts	−3.5 pts	+6.8 pts
1 year	−7.4%	+44.5%	−23.1 pts	+28.8 pts	−31.2 pts	+20.8 pts
3 years	+7.5%	+57.9%	−77.5 pts	−27.1 pts	−102.5 pts	−52.1 pts
Since launch HEAL Jul 2020 · HELX Feb 2020	−36.6%	+87.4%	−192.9 pts	−94.7 pts	−230.4 pts	−187.2 pts

HEAL and HELX over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

HEAL

Global X HealthTech ETF · Holds 43 stocks in healthcare innovation and GLP-1, 27% of its weight in S&P 500 companies

HELX

Franklin Genomic Advancements ETF · Holds 61 stocks in healthcare innovation and GLP-1, 15% of its weight in S&P 500 companies

Issuer Global X Franklin

Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1

In the S&P 500 27.0% 15.1%

Active share vs the S&P 500 99.6% 97.2%

In the Nasdaq-100 8.3% 10.0%

Holdings 43 61

Top ten, share of the fund 47.6% 47.7%

Expense ratio 0.50% 0.50%

Fee for the differing part 0.50% 0.51%

Total return, 1 year −7.4% +44.5%

vs the S&P 500 −23.1 pts +28.8 pts

vs the Nasdaq-100 −31.2 pts +20.8 pts

Below its high −56.4% −23.0%

Net assets $31m $33m

HEAL and HELX on the same fields, as of Sep 30, 2026. Source: ETFIQ.

HEAL in plain words

By weight, 27% of HEAL's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 48% of the fund across 43 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned −7.4% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 23.1 pts. It sits 56.4% below its all-time high of Feb 12, 2021.

HELX in plain words

By weight, 15% of HELX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 48% of the fund across 61 positions, as filed for Jun 30, 2026. Over the year to Sep 30, 2026 the fund returned +44.5% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 28.8 pts. It sits 23.0% below its all-time high of Sep 7, 2021.

Questions people ask

Do HEAL and HELX hold the same stocks?: By their latest filings, 4% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, HEAL or HELX?: HEAL has 27% of its weight in S&P 500 names and HELX has 15%, so HEAL differs more from the index.
Which is cheaper, HEAL or HELX?: HEAL charges 0.50% a year and HELX charges 0.50%, so HEAL is cheaper. Fees come from each fund's prospectus.

Other comparisons

HEAL vs LGHT HEAL vs OZEM HEAL vs THNR HEAL vs WDNA HELX vs LGHT HELX vs OZEM HELX vs THNR HELX vs WDNA

HEAL on its own →HELX on its own →How every figure is computed →Standards and sources →

Where these figures came from

HEAL filings on SEC EDGAR ↗HEAL prospectus with the expense ratio (SEC) ↗Global X page for HEAL ↗HELX filings on SEC EDGAR ↗HELX prospectus with the expense ratio (SEC) ↗Franklin website ↗

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement. A comparison is not a recommendation.

Cite this page

ETFIQ, HEAL against HELX, data as of Sep 30, 2026. https://etfiq.com/compare/themes/heal-vs-helx

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.