BMED vs HELX: which is really different?

BMED and HELX hold 14% of their weight in the same names, and HELX returned +44.5% over the year. iShares Health Innovation Active ETF and Franklin Genomic Advancements ETF.

61.5%
BMED in the S&P 500
15.1%
HELX in the S&P 500
+29.3%
BMED total return, 1 year
+44.5%
HELX total return, 1 year
BMED · 1 year to Sep 30, 202639% of its weight is outside the S&P 500
39% of its weight is outside the S&P 50062% of BMED's weight is in S&P 500 companies and 39% is outside the index62%39%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 96% · top ten 43% of the fund · 60 holdings filed Sep 30, 2026 · Nasdaq-100: 13% in39% of its weight is outside the S&P 50062% of BMED's weight is in S&P 500 companies and 39% is outside the index62%39%in the S&P 500outsideactive share 96% · top ten 43% of the fund

62% of BMED's weight is in S&P 500 companies and 39% is outside the index

HELX · 1 year to Sep 30, 202685% of its weight is outside the S&P 500
85% of its weight is outside the S&P 50015% of HELX's weight is in S&P 500 companies and 85% is outside the index15%85%in the S&P 500of its weight outside the S&P 500active share 97% · top ten 48% of the fund · 61 holdings filed Jun 30, 2026 · Nasdaq-100: 10% in85% of its weight is outside the S&P 50015% of HELX's weight is in S&P 500 companies and 85% is outside the index15%85%inof its weight outside the S&P 500active share 97% · top ten 48% of the fund

15% of HELX's weight is in S&P 500 companies and 85% is outside the index

ETFIQ Off-Index Score · HELX scores higherHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, BMED and HELX hold 14% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and Sep 30, 2026.

half

14% in common

Positions both hold, largest shared weight first
Holding BMED HELX
VERTEX PHARMACEUTICALS 3.35% 2.78%
ARGENX SE ADR 1.92% 1.66%
TEMPUS AI CLASS A 1.57% 1.97%
GUARDANT HEALTH 1.51% 9.21%
NEUROCRINE BIOSCIENCES 1.34% 1.87%
CHARLES RIVER LABORATORIES INTERNA 2.09% 1.28%
AXSOME THERAPEUTICS 0.96% 0.83%
THERMO FISHER SCIENTIFIC INC 4.41% 0.77%
IQVIA HOLDINGS 3.75% 0.76%
AGILENT TECHNOLOGIES INC 1.24% 0.59%
DANAHER 5.19% 0.58%
PTC THERAPEUTICS 0.47% 1.48%
Only in BMED
MODERNA 5.19%
GILEAD SCIENCES 5.00%
ABBVIE 4.61%
JOHNSON & JOHNSON 4.17%
WATERS CORP 3.66%
BIOGEN 3.52%
METTLER TOLEDO 3.33%
MERCK & CO INC 3.10%
Only in HELX
NATERA INC 7.56%
KRYSTAL BIOTECH INC 6.41%
LIGAND PHARMACEUTICALS INC 4.68%
ADAPTIVE BIOTECHNOLOGIES CORP 4.04%
UNITED THERAPEUTICS CORP 3.55%
BRIDGEBIO PHARMA INC 3.54%
ELI LILLY & COMPANY 2.99%
TWIST BIOSCIENCE CORP 2.89%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

14% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowBMEDHELXBMEDHELXBMEDHELX
3 months+12.6%+9.9%+10.1 pts+7.4 pts+10.5 pts+7.8 pts
6 months+19.4%+33.6%+2.4 pts+16.6 pts−7.5 pts+6.8 pts
1 year+29.3%+44.5%+13.6 pts+28.8 pts+5.5 pts+20.8 pts
3 years+54.5%+57.9%−30.5 pts−27.1 pts−55.5 pts−52.1 pts
Since launch
BMED Oct 2020 · HELX Feb 2020
+35.9%+87.4%−109.5 pts−94.7 pts−135.6 pts−187.2 pts

BMED and HELX over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

BMED
iShares Health Innovation Active ETF · Holds 60 stocks in healthcare innovation and GLP-1, 62% of its weight in S&P 500 companies
HELX
Franklin Genomic Advancements ETF · Holds 61 stocks in healthcare innovation and GLP-1, 15% of its weight in S&P 500 companies
Issuer iShares Franklin
Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1
In the S&P 500 61.5% 15.1%
Active share vs the S&P 500 95.6% 97.2%
In the Nasdaq-100 13.2% 10.0%
Holdings 60 61
Top ten, share of the fund 42.9% 47.7%
Expense ratio 0.55% 0.50%
Fee for the differing part 0.58% 0.51%
Total return, 1 year +29.3% +44.5%
vs the S&P 500 +13.6 pts +28.8 pts
vs the Nasdaq-100 +5.5 pts +20.8 pts
Below its high −1.0% −23.0%
Net assets $14m $33m

BMED and HELX on the same fields, as of Sep 30, 2026. Source: ETFIQ.

BMED in plain words

By weight, 62% of BMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 96%. The top ten holdings are 43% of the fund across 60 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned +29.3% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 13.6 pts.

HELX in plain words

By weight, 15% of HELX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 48% of the fund across 61 positions, as filed for Jun 30, 2026. Over the year to Sep 30, 2026 the fund returned +44.5% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 28.8 pts. It sits 23.0% below its all-time high of Sep 7, 2021.

Questions people ask

Do BMED and HELX hold the same stocks?
By their latest filings, 14% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BMED or HELX?
BMED has 62% of its weight in S&P 500 names and HELX has 15%, so HELX differs more from the index.
Which is cheaper, BMED or HELX?
BMED charges 0.55% a year and HELX charges 0.50%, so HELX is cheaper. Fees come from each fund's prospectus.
Cite this page

ETFIQ, BMED against HELX, data as of Sep 30, 2026. https://etfiq.com/compare/themes/bmed-vs-helx

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.