BMED vs WDNA: which is really different?

BMED and WDNA hold 25% of their weight in the same names, and WDNA returned +58.6% over the year. iShares Health Innovation Active ETF and WisdomTree BioRevolution Fund.

61.5%
BMED in the S&P 500
25.9%
WDNA in the S&P 500
+29.3%
BMED total return, 1 year
+58.6%
WDNA total return, 1 year
BMED · 1 year to Sep 30, 202639% of its weight is outside the S&P 500
39% of its weight is outside the S&P 50062% of BMED's weight is in S&P 500 companies and 39% is outside the index62%39%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 96% · top ten 43% of the fund · 60 holdings filed Sep 30, 2026 · Nasdaq-100: 13% in39% of its weight is outside the S&P 50062% of BMED's weight is in S&P 500 companies and 39% is outside the index62%39%in the S&P 500outsideactive share 96% · top ten 43% of the fund

62% of BMED's weight is in S&P 500 companies and 39% is outside the index

WDNA · 1 year to Sep 30, 202674% of its weight is outside the S&P 500
74% of its weight is outside the S&P 50026% of WDNA's weight is in S&P 500 companies and 74% is outside the index26%74%in the S&P 500of its weight outside the S&P 500active share 95% · top ten 31% of the fund · 80 holdings filed Jun 30, 2026 · Nasdaq-100: 6% in74% of its weight is outside the S&P 50026% of WDNA's weight is in S&P 500 companies and 74% is outside the index26%74%inoutside the S&P 500active share 95% · top ten 31% of the fund

26% of WDNA's weight is in S&P 500 companies and 74% is outside the index

ETFIQ Off-Index Score · BMED scores higherHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, BMED and WDNA hold 25% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and Sep 30, 2026.

half

25% in common

Positions both hold, largest shared weight first
Holding BMED WDNA
MODERNA 5.19% 4.15%
JOHNSON & JOHNSON 4.17% 2.97%
TEMPUS AI CLASS A 1.57% 2.29%
AMGEN INC 2.45% 1.54%
THERMO FISHER SCIENTIFIC INC 4.41% 1.52%
GILEAD SCIENCES 5.00% 1.51%
ROIVANT SCIENCES LTD 1.37% 1.73%
PFIZER 1.52% 1.35%
VERTEX PHARMACEUTICALS 3.35% 1.34%
NOVARTIS AG 1.83% 1.33%
ARGENX SE ADR 1.92% 0.94%
PROTAGONIST THERAPEUTICS 0.88% 1.03%
Only in BMED
ABBVIE 4.61%
IQVIA HOLDINGS 3.75%
WATERS CORP 3.66%
METTLER TOLEDO 3.33%
EDWARDS LIFESCIENCES 2.96%
ROCHE PS PAR AG 2.58%
DEXCOM INC 2.43%
INCYTE CORP 2.31%
Only in WDNA
TWIST BIOSCIENCE CORP 5.96%
ELI LILLY & COMPANY 4.08%
UNITED THERAPEUTICS CORP 2.45%
NATERA INC 2.33%
IMMUNOME INC 2.26%
STRUCTURE THERAPEUTICS INC 2.12%
STOKE THERAPEUTICS INC 2.10%
BEAM THERAPEUTICS INC 2.09%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

25% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowBMEDWDNABMEDWDNABMEDWDNA
3 months+12.6%+16.6%+10.1 pts+14.1 pts+10.5 pts+14.5 pts
6 months+19.4%+36.5%+2.4 pts+19.5 pts−7.5 pts+9.6 pts
1 year+29.3%+58.6%+13.6 pts+42.9 pts+5.5 pts+34.8 pts
3 years+54.5%+69.0%−30.5 pts−16.0 pts−55.5 pts−41.0 pts
Since launch
BMED Oct 2020 · WDNA Jun 2021
+35.9%+2.8%−109.5 pts−93.2 pts−135.6 pts−128.7 pts

BMED and WDNA over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

BMED
iShares Health Innovation Active ETF · Holds 60 stocks in healthcare innovation and GLP-1, 62% of its weight in S&P 500 companies
WDNA
WisdomTree BioRevolution Fund · Holds 80 stocks in healthcare innovation and GLP-1, 26% of its weight in S&P 500 companies
Issuer iShares WisdomTree
Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1
In the S&P 500 61.5% 25.9%
Active share vs the S&P 500 95.6% 95.3%
In the Nasdaq-100 13.2% 5.8%
Holdings 60 80
Top ten, share of the fund 42.9% 30.7%
Expense ratio 0.55% 0.45%
Fee for the differing part 0.58% 0.47%
Total return, 1 year +29.3% +58.6%
vs the S&P 500 +13.6 pts +42.9 pts
vs the Nasdaq-100 +5.5 pts +34.8 pts
Below its high −1.0% −8.1%
Net assets $14m $4m

BMED and WDNA on the same fields, as of Sep 30, 2026. Source: ETFIQ.

BMED in plain words

By weight, 62% of BMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 96%. The top ten holdings are 43% of the fund across 60 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned +29.3% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 13.6 pts.

WDNA in plain words

By weight, 26% of WDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 31% of the fund across 80 positions, as filed for Jun 30, 2026. Over the year to Sep 30, 2026 the fund returned +58.6% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 42.9 pts. It sits 8.1% below its all-time high of Sep 2, 2021.

Questions people ask

Do BMED and WDNA hold the same stocks?
By their latest filings, 25% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BMED or WDNA?
BMED has 62% of its weight in S&P 500 names and WDNA has 26%, so BMED differs more from the index.
Which is cheaper, BMED or WDNA?
BMED charges 0.55% a year and WDNA charges 0.45%, so WDNA is cheaper. Fees come from each fund's prospectus.
Cite this page

ETFIQ, BMED against WDNA, data as of Sep 30, 2026. https://etfiq.com/compare/themes/bmed-vs-wdna

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.