Do THNR and WDNA hold the same stocks?

By their latest filings, 16% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, THNR or WDNA?

THNR has 40% of its weight in S&P 500 names and WDNA has 26%, so THNR differs more from the index.

Which is cheaper, THNR or WDNA?

THNR charges 0.59% a year and WDNA charges 0.45%, so WDNA is cheaper. Fees come from each fund's prospectus.

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THNR vs WDNA: which is really different?

THNR and WDNA hold 16% of their weight in the same names, and WDNA returned +58.6% over the year. Amplify Weight Loss Drug & Treatment ETF and WisdomTree BioRevolution Fund.

39.5%

THNR in the S&P 500

25.9%

WDNA in the S&P 500

+9.2%

THNR total return, 1 year

+58.6%

WDNA total return, 1 year

THNR · 1 year to Sep 30, 202661% of its weight is outside the S&P 500

40% of THNR's weight is in S&P 500 companies and 61% is outside the index

WDNA · 1 year to Sep 30, 202674% of its weight is outside the S&P 500

26% of WDNA's weight is in S&P 500 companies and 74% is outside the index

ETFIQ Off-Index Score · THNR scores higherHow much of it is not the index it is sold as an alternative to?

THNR 37.7

WDNA 34

0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, THNR and WDNA hold 16% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and Oct 1, 2026.

50%

half

16% in common

Positions both hold, largest shared weight first

Holding THNR WDNA

Eli Lilly & Co 10.07% 4.08%

Structure Therapeutics Inc 3.30% 2.12%

AstraZeneca PLC 5.27% 1.83%

Amgen Inc 5.75% 1.54%

Gilead Sciences Inc 4.55% 1.51%

Arrowhead Pharmaceuticals Inc 4.01% 1.48%

Pfizer Inc 5.38% 1.35%

Viking Therapeutics Inc 4.55% 0.93%

Merck & Co Inc 4.55% 0.70%

Regeneron Pharmaceuticals Inc 4.64% 0.54%

Only in THNR

Novo Nordisk A/S 8.42%

CSPC Pharmaceutical Group Ltd 5.82%

Innovent Biologics Inc 5.30%

AbbVie Inc 4.56%

Roche Holding AG 4.56%

Chugai Pharmaceutical Co Ltd 4.52%

Zealand Pharma A/S 3.95%

Hanmi Pharm Co Ltd 3.52%

Only in WDNA

TWIST BIOSCIENCE CORP 5.96%

MODERNA INC 4.15%

JOHNSON & JOHNSON 2.97%

UNITED THERAPEUTICS CORP 2.45%

NATERA INC 2.33%

TEMPUS AI INC 2.29%

IMMUNOME INC 2.26%

STOKE THERAPEUTICS INC 2.10%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

16% of the two portfolios are the same securities at the same weight.

Performance, window by window

	Total return		vs the S&P 500		vs the Nasdaq-100
Window	THNR	WDNA	THNR	WDNA	THNR	WDNA
3 months	−1.8%	+16.6%	−4.3 pts	+14.1 pts	−3.9 pts	+14.5 pts
6 months	+0.7%	+36.5%	−16.3 pts	+19.5 pts	−26.1 pts	+9.6 pts
1 year	+9.2%	+58.6%	−6.5 pts	+42.9 pts	−14.6 pts	+34.8 pts
3 years	not published	+69.0%	not published	−16.0 pts	not published	−41.0 pts
Since launch THNR May 2024 · WDNA Jun 2021	+1.6%	+2.8%	−46.1 pts	−93.2 pts	−62.8 pts	−128.7 pts

THNR and WDNA over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

THNR

Amplify Weight Loss Drug & Treatment ETF · Holds 22 stocks in healthcare innovation and GLP-1, 40% of its weight in S&P 500 companies

WDNA

WisdomTree BioRevolution Fund · Holds 80 stocks in healthcare innovation and GLP-1, 26% of its weight in S&P 500 companies

Issuer Amplify WisdomTree

Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1

In the S&P 500 39.5% 25.9%

Active share vs the S&P 500 96.5% 95.3%

In the Nasdaq-100 14.9% 5.8%

Holdings 22 80

Top ten, share of the fund 59.8% 30.7%

Expense ratio 0.59% 0.45%

Fee for the differing part 0.61% 0.47%

Total return, 1 year +9.2% +58.6%

vs the S&P 500 −6.5 pts +42.9 pts

vs the Nasdaq-100 −14.6 pts +34.8 pts

Below its high −9.9% −8.1%

Net assets $6m $4m

THNR and WDNA on the same fields, as of Sep 30, 2026. Source: ETFIQ.

THNR in plain words

By weight, 40% of THNR's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 96%. The top ten holdings are 60% of the fund across 22 positions, as published by its issuer for Oct 1, 2026. Over the year to Sep 30, 2026 the fund returned +9.2% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 6.5 pts. It sits 9.9% below its all-time high of Aug 25, 2026.

WDNA in plain words

By weight, 26% of WDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 31% of the fund across 80 positions, as filed for Jun 30, 2026. Over the year to Sep 30, 2026 the fund returned +58.6% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 42.9 pts. It sits 8.1% below its all-time high of Sep 2, 2021.

Questions people ask

Do THNR and WDNA hold the same stocks?: By their latest filings, 16% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, THNR or WDNA?: THNR has 40% of its weight in S&P 500 names and WDNA has 26%, so THNR differs more from the index.
Which is cheaper, THNR or WDNA?: THNR charges 0.59% a year and WDNA charges 0.45%, so WDNA is cheaper. Fees come from each fund's prospectus.

Other comparisons

THNR vs HEAL THNR vs HELX THNR vs BMED THNR vs EKG WDNA vs BMED WDNA vs HELX WDNA vs LGHT WDNA vs OZEM

THNR on its own →WDNA on its own →How every figure is computed →Standards and sources →

Where these figures came from

THNR filings on SEC EDGAR ↗THNR prospectus with the expense ratio (SEC) ↗Amplify page for THNR ↗WDNA filings on SEC EDGAR ↗WDNA prospectus with the expense ratio (SEC) ↗WisdomTree page for WDNA ↗

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement. A comparison is not a recommendation.

Cite this page

ETFIQ, THNR against WDNA, data as of Sep 30, 2026. https://etfiq.com/compare/themes/thnr-vs-wdna

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.