Do OZEM and THNR hold the same stocks?

By their latest filings, 68% of their books are the same securities at the same weight, which is close to holding one of them twice. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, OZEM or THNR?

OZEM has 27% of its weight in S&P 500 names and THNR has 40%, so OZEM differs more from the index.

Which is cheaper, OZEM or THNR?

OZEM charges 0.59% a year and THNR charges 0.59%, so OZEM is cheaper. Fees come from each fund's prospectus.

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OZEM vs THNR: which is really different?

OZEM and THNR hold 68% of their weight in the same names, and OZEM returned +14.0% over the year. Roundhill GLP-1 & Weight Loss ETF and Amplify Weight Loss Drug & Treatment ETF.

26.6%

OZEM in the S&P 500

39.5%

THNR in the S&P 500

+14.0%

OZEM total return, 1 year

+9.2%

THNR total return, 1 year

OZEM · 1 year to Sep 30, 202673% of its weight is outside the S&P 500

27% of OZEM's weight is in S&P 500 companies and 73% is outside the index

THNR · 1 year to Sep 30, 202661% of its weight is outside the S&P 500

40% of THNR's weight is in S&P 500 companies and 61% is outside the index

ETFIQ Off-Index Score · OZEM scores higherHow much of it is not the index it is sold as an alternative to?

OZEM 46.9

THNR 37.7

0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, OZEM and THNR hold 68% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Oct 1, 2026 and Sep 30, 2026.

50%

half

68% in common

Positions both hold, largest shared weight first

Holding OZEM THNR

Eli Lilly & Co 12.69% 10.07%

Novo Nordisk A/S 11.09% 8.42%

CSPC Pharmaceutical Group Ltd 6.52% 5.82%

Pfizer Inc 7.69% 5.38%

Viking Therapeutics Inc 5.47% 4.55%

Chugai Pharmaceutical Co Ltd 4.64% 4.52%

Amgen Inc 4.37% 5.75%

Zealand Pharma A/S 3.94% 3.95%

AstraZeneca PLC 3.79% 5.27%

Hanmi Pharm Co Ltd 4.33% 3.52%

Roche Holding AG 3.10% 4.56%

Innovent Biologics Inc 2.47% 5.30%

Only in OZEM

Ascletis Pharma Inc 4.39%

United Laboratories International Holdings Ltd/The 2.90%

Hansoh Pharmaceutical Group Co Ltd 2.85%

Gubra A/S 2.31%

MBX Biosciences Inc 2.08%

Rhythm Pharmaceuticals Inc 1.47%

Shionogi & Co Ltd 1.32%

First American Government Obligations Fund 12/01/2031 0.37%

Only in THNR

Regeneron Pharmaceuticals Inc 4.64%

AbbVie Inc 4.56%

Merck & Co Inc 4.55%

Arrowhead Pharmaceuticals Inc 4.01%

Invesco Government & Agency Portfolio 12/31/2031 3.04%

Cash & Other 0.91%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

68% of the two portfolios are the same securities at the same weight.

Performance, window by window

	Total return		vs the S&P 500		vs the Nasdaq-100
Window	OZEM	THNR	OZEM	THNR	OZEM	THNR
3 months	−4.9%	−1.8%	−7.5 pts	−4.3 pts	−7.1 pts	−3.9 pts
6 months	−3.5%	+0.7%	−20.5 pts	−16.3 pts	−30.4 pts	−26.1 pts
1 year	+14.0%	+9.2%	−1.7 pts	−6.5 pts	−9.8 pts	−14.6 pts
Since launch OZEM May 2024 · THNR May 2024	+23.1%	+1.6%	−24.7 pts	−46.1 pts	−41.3 pts	−62.8 pts

OZEM and THNR over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

OZEM

Roundhill GLP-1 & Weight Loss ETF · Holds 26 stocks in healthcare innovation and GLP-1, 27% of its weight in S&P 500 companies

THNR

Amplify Weight Loss Drug & Treatment ETF · Holds 22 stocks in healthcare innovation and GLP-1, 40% of its weight in S&P 500 companies

Issuer Roundhill Amplify

Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1

In the S&P 500 26.6% 39.5%

Active share vs the S&P 500 97.8% 96.5%

In the Nasdaq-100 6.2% 14.9%

Holdings 26 22

Top ten, share of the fund 66.4% 59.8%

Expense ratio 0.59% 0.59%

Fee for the differing part 0.60% 0.61%

Total return, 1 year +14.0% +9.2%

vs the S&P 500 −1.7 pts −6.5 pts

vs the Nasdaq-100 −9.8 pts −14.6 pts

Below its high −16.8% −9.9%

Net assets $58m $6m

OZEM and THNR on the same fields, as of Sep 30, 2026. Source: ETFIQ.

OZEM in plain words

By weight, 27% of OZEM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 66% of the fund across 26 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned +14.0% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 1.7 pts. It sits 16.8% below its all-time high of Jan 26, 2026.

THNR in plain words

By weight, 40% of THNR's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 96%. The top ten holdings are 60% of the fund across 22 positions, as published by its issuer for Oct 1, 2026. Over the year to Sep 30, 2026 the fund returned +9.2% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 6.5 pts. It sits 9.9% below its all-time high of Aug 25, 2026.

Questions people ask

Do OZEM and THNR hold the same stocks?: By their latest filings, 68% of their books are the same securities at the same weight, which is close to holding one of them twice. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, OZEM or THNR?: OZEM has 27% of its weight in S&P 500 names and THNR has 40%, so OZEM differs more from the index.
Which is cheaper, OZEM or THNR?: OZEM charges 0.59% a year and THNR charges 0.59%, so OZEM is cheaper. Fees come from each fund's prospectus.

Other comparisons

OZEM vs BMED OZEM vs EKG OZEM vs HEAL OZEM vs WDNA THNR vs WDNA THNR vs BMED THNR vs EKG THNR vs HEAL

OZEM on its own →THNR on its own →How every figure is computed →Standards and sources →

Where these figures came from

OZEM filings on SEC EDGAR ↗OZEM prospectus with the expense ratio (SEC) ↗Roundhill page for OZEM ↗THNR filings on SEC EDGAR ↗THNR prospectus with the expense ratio (SEC) ↗Amplify page for THNR ↗

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement. A comparison is not a recommendation.

Cite this page

ETFIQ, OZEM against THNR, data as of Sep 30, 2026. https://etfiq.com/compare/themes/ozem-vs-thnr

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.