The cheapest healthcare innovation ETFs
See 8 funds ranked by the annual fee the fund charges. Updated Oct 20, 2026. A fee is one fact, not a verdict. Funds on one theme can hold different companies, and the holdings are on the theme page.
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| # | Ticker | Fund | Fee ↑ | Net assets | Weight in S&P 500 companies | Total return, 1Y |
|---|---|---|---|---|---|---|
| 1 | WDNA | WisdomTree BioRevolution Fund | 0.45% | $3m | 25.9% | +36.0% |
| 2 | HEAL | Global X HealthTech ETF | 0.50% | $31m | 28.8% | −6.1% |
| 3 | HELX | Franklin Genomic Advancements ETF | 0.50% | $34m | 14.9% | +25.1% |
| 4 | BMED | iShares Health Innovation Active ETF | 0.55% | $14m | 58.4% | +25.4% |
| 5 | OZEM | Roundhill GLP-1 & Weight Loss ETF | 0.59% | $56m | 29.3% | +8.8% |
| 6 | THNR | Amplify Weight Loss Drug & Treatment ETF | 0.59% | $6m | 44.8% | +7.8% |
| 7 | EKG | First Trust Nasdaq Lux Digital Health So | 0.65% | $10m | 41.4% | +31.2% |
| 8 | LGHT | Langar Global HealthTech ETF | 0.85% | $2m | 57.9% | +10.1% |
Method
The 8 of 8 ETFs in the healthcare innovation and glp-1 theme that publish an expense ratio, cheapest first. Across the funds listed here the annual fee runs from 0.5% to 0.8%.
The rest of the method
A fee is the one number a fund controls and the one a holder always pays. The list sorts one published figure, with no scoring or weighting. Every fund ETFIQ covers in this category is eligible, closed funds included.
ETFIQ links to the documents behind every figure; a link is not an endorsement. A ranking is not a recommendation or an opinion.
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ETFIQ, The cheapest healthcare innovation ETFs, ranked by the annual fee the fund charges, data as of Oct 20, 2026. https://etfiq.com/rankings/themes-cheapest-health-innovation
ETFIQ. (Oct 20, 2026). The cheapest healthcare innovation ETFs, ranked by the annual fee the fund charges. Retrieved from https://etfiq.com/rankings/themes-cheapest-health-innovation
[The cheapest healthcare innovation ETFs, ranked by the annual fee the fund charges (ETFIQ, Oct 20, 2026)](https://etfiq.com/rankings/themes-cheapest-health-innovation)
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