EKG vs HEAL: which is really different?

EKG and HEAL hold 46% of their weight in the same names, and EKG returned +36.5% over the year. First Trust Nasdaq Lux Digital Health Solutions ETF and Global X HealthTech ETF.

39.0%
EKG in the S&P 500
27.0%
HEAL in the S&P 500
+36.5%
EKG total return, 1 year
−7.4%
HEAL total return, 1 year
EKG · 1 year to Sep 30, 202661% of its weight is outside the S&P 500
61% of its weight is outside the S&P 50039% of EKG's weight is in S&P 500 companies and 61% is outside the index39%61%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 58% of the fund · 52 holdings filed Sep 30, 2026 · Nasdaq-100: 15% in61% of its weight is outside the S&P 50039% of EKG's weight is in S&P 500 companies and 61% is outside the index39%61%in the S&P 500outside the S&P 500active share 100% · top ten 58% of the fund

39% of EKG's weight is in S&P 500 companies and 61% is outside the index

HEAL · 1 year to Sep 30, 202673% of its weight is outside the S&P 500
73% of its weight is outside the S&P 50027% of HEAL's weight is in S&P 500 companies and 73% is outside the index27%73%in the S&P 500of its weight outside the S&P 500active share 100% · top ten 48% of the fund · 43 holdings filed Sep 30, 2026 · Nasdaq-100: 8% in73% of its weight is outside the S&P 50027% of HEAL's weight is in S&P 500 companies and 73% is outside the index27%73%inoutside the S&P 500active share 100% · top ten 48% of the fund

27% of HEAL's weight is in S&P 500 companies and 73% is outside the index

ETFIQ Off-Index Score · EKG scores higherHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.0, the highest

A percentile among the 375 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, EKG and HEAL hold 46% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 30, 2026.

half

46% in common

Positions both hold, largest shared weight first
Holding EKG HEAL
IQVIA Holdings Inc. 7.65% 6.14%
Veeva Systems Inc. (Class A) 7.43% 6.00%
DexCom, Inc. 7.05% 5.07%
ResMed Inc. 3.42% 3.89%
Tempus AI, Inc. (Class A) 3.22% 5.37%
Intuitive Surgical, Inc. 8.03% 3.21%
Oscar Health, Inc. (Class A) 2.69% 5.65%
Insulet Corporation 2.68% 2.69%
Hinge Health, Inc. (Class A) 2.07% 2.71%
Hims & Hers Health, Inc. 2.03% 3.92%
Heartflow, Inc. 1.18% 2.83%
Doximity, Inc. (Class A) 1.05% 3.00%
Only in EKG
Natera, Inc. 9.54%
Illumina, Inc. 4.76%
Guardant Health, Inc. 4.17%
Globus Medical, Inc. (Class A) 3.17%
QIAGEN N.V. 3.05%
Twist Bioscience Corporation 2.87%
Align Technology, Inc. 2.70%
10X Genomics, Inc. (Class A) 2.44%
Only in HEAL
PRO MEDICUS LTD 4.18%
GE HEALTHCARE TECHNOLOGY 3.86%
KONINKLIJKE PHILIPS NV 3.36%
DEMANT A/S 3.33%
NURIX THERAPEUTICS INC 1.92%
ALIBABA HEALTH INFORMATION T 1.90%
RECURSION PHARMACEUTICALS-A 1.78%
4DMEDICAL LTD 1.53%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

46% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowEKGHEALEKGHEALEKGHEAL
3 months+21.3%+3.3%+18.8 pts+0.8 pts+19.1 pts+1.2 pts
6 months+45.4%+23.4%+28.5 pts+6.4 pts+18.6 pts−3.5 pts
1 year+36.5%−7.4%+20.8 pts−23.1 pts+12.7 pts−31.2 pts
3 years+68.7%+7.5%−16.3 pts−77.5 pts−41.3 pts−102.5 pts
Since launch
EKG Mar 2022 · HEAL Jul 2020
+19.7%−36.6%−62.9 pts−192.9 pts−96.4 pts−230.4 pts

EKG and HEAL over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

EKG
First Trust Nasdaq Lux Digital Health Solutions ETF · Holds 52 stocks in healthcare innovation and GLP-1, 39% of its weight in S&P 500 companies
HEAL
Global X HealthTech ETF · Holds 43 stocks in healthcare innovation and GLP-1, 27% of its weight in S&P 500 companies
Issuer First Trust Global X
Theme Healthcare innovation and GLP-1 Healthcare innovation and GLP-1
In the S&P 500 39.0% 27.0%
Active share vs the S&P 500 99.6% 99.6%
In the Nasdaq-100 15.1% 8.3%
Holdings 52 43
Top ten, share of the fund 58.4% 47.6%
Expense ratio 0.65% 0.50%
Fee for the differing part 0.65% 0.50%
Total return, 1 year +36.5% −7.4%
vs the S&P 500 +20.8 pts −23.1 pts
vs the Nasdaq-100 +12.7 pts −31.2 pts
Below its high 0.0% −56.4%
Net assets $5m $31m

EKG and HEAL on the same fields, as of Sep 30, 2026. Source: ETFIQ.

EKG in plain words

By weight, 39% of EKG's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 58% of the fund across 52 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned +36.5% with distributions reinvested against +15.7% for the S&P 500, so a holder was ahead by 20.8 pts.

HEAL in plain words

By weight, 27% of HEAL's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 48% of the fund across 43 positions, as published by its issuer for Sep 30, 2026. Over the year to Sep 30, 2026 the fund returned −7.4% with distributions reinvested against +15.7% for the S&P 500, so a holder was behind by 23.1 pts. It sits 56.4% below its all-time high of Feb 12, 2021.

Questions people ask

Do EKG and HEAL hold the same stocks?
By their latest filings, 46% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, EKG or HEAL?
EKG has 39% of its weight in S&P 500 names and HEAL has 27%, so EKG differs more from the index.
Which is cheaper, EKG or HEAL?
EKG charges 0.65% a year and HEAL charges 0.50%, so HEAL is cheaper. Fees come from each fund's prospectus.
Cite this page

ETFIQ, EKG against HEAL, data as of Sep 30, 2026. https://etfiq.com/compare/themes/ekg-vs-heal

Open data

Free to use with attribution. Every figure is calculated from a named public source; the method is at etfiq.com/methodology.