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Data as of .

FITE vs FMED: which is really different?

FITE and FMED hold 0% of their weight in the same names, and FITE returned more over the year.

State Street(R) SPDR(R) S&P Kensho Future Security ETF and Fidelity Disruptive Medicine ETF.

27.1%FITE in the S&P 500
25.4%FMED in the S&P 500
+30.7%FITE total return, 1 year
+28.3%FMED total return, 1 year

ETFIQ Off-Index Score: FMED scores higher

How much of it is not the index it is sold as an alternative to?

FITE 33.1FMED 40.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

FITE73% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
27%73%in the S&P 500of its weight outside the S&P 500active share 95% · top ten 20% of the fund · 80 holdings filed Sep 17, 2026 · Nasdaq-100: 11% in27%73%inoutside the S&P 500active share 95% · top ten 20% of the fund
FMED75% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
25%75%in the S&P 500of its weight outside the S&P 500active share 97% · top ten 32% of the fund · 68 holdings filed May 31, 2026 · Nasdaq-100: 9% in25%75%inoutside the S&P 500active share 97% · top ten 32% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, FITE and FMED hold 0% of their money in the same securities at the same weight.

Only in each
Only in FITEOnly in FMED
RAPID7 INC 2.23%UCB SA 4.75%
OKTA INC 2.14%LIFESTANCE HEALTH GROUP INC 4.29%
QUALYS INC 2.09%DANAHER CORP 3.43%
ZSCALER INC 2.05%10X GENOMICS INC 3.12%
SENTINELONE INC CLASS A 2.03%INTUITIVE SURGICAL INC 2.93%
CLOUDFLARE INC CLASS A 1.97%COGENT BIOSCIENCES INC 2.86%
CROWDSTRIKE HOLDINGS INC A 1.97%ALNYLAM PHARMACEUTICALS INC 2.80%
RUBRIK INC A 1.96%ARGENX SE 2.79%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 17, 2026.

Performance, window by window

FITE and FMED over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
FITEFMEDFITEFMEDFITEFMED
3 months+2.7%+21.3%+0.5 pts+19.0 pts+5.2 pts+23.7 pts
6 months+25.9%+32.3%+7.9 pts+14.3 pts+1.7 pts+8.0 pts
1 year+30.7%+28.3%+14.1 pts+11.7 pts+8.9 pts+6.5 pts
3 years+130.9%+39.6%+52.5 pts−38.8 pts+32.8 pts−58.5 pts
Since launch+285.5%+25.8%+59.9 pts−57.6 pts−101.9 pts−78.1 pts
Open the live comparison on ETFIQ
FITE and FMED on the same fields, as of Sep 18, 2026. Source: ETFIQ.
FITE
State Street(R) SPDR(R) S&P Kensho Future Security ETF
Holds 80 stocks in broad innovation and megatrends, 27% of its weight in S&P 500 companies
FMED
Fidelity Disruptive Medicine ETF
Holds 68 stocks in broad innovation and megatrends, 25% of its weight in S&P 500 companies
IssuerState StreetFidelity
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50027.1%25.4%
Active share vs the S&P 50095.3%97.1%
In the Nasdaq-10011.2%8.7%
Holdings8068
Top ten, share of the fund20.2%31.5%
Expense ratio0.45%0.50%
Fee for the differing part0.47%0.51%
Total return, 1 year+30.7%+28.3%
vs the S&P 500+14.1 pts+11.7 pts
vs the Nasdaq-100+8.9 pts+6.5 pts
Below its high−8.2%−3.8%
Net assets$151m$52m

FITE in plain words

By weight, 27% of FITE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 20% of the fund across 80 positions, as published by its issuer for Sep 17, 2026. Over the year to Sep 18, 2026 the fund returned +30.7% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 14.1 pts. It sits 8.2% below its all-time high of Aug 13, 2026.

FMED in plain words

By weight, 25% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 32% of the fund across 68 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +28.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 11.7 pts.

Questions people ask

Do FITE and FMED hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FITE or FMED?
FITE has 27% of its weight in S&P 500 names and FMED has 25%, so FMED differs more from the index.
Which is cheaper, FITE or FMED?
FITE charges 0.45% a year and FMED charges 0.50%, so FITE is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

FITE against FMED, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, FITE against FMED, data as of Sep 18, 2026. https://etfiq.com/compare/themes/fite-vs-fmed Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources