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Data as of .

AOTG vs FMED: which is really different?

AOTG and FMED hold 0% of their weight in the same names, and FMED returned more over the year.

AOT Growth and Innovation ETF and Fidelity Disruptive Medicine ETF.

77.4%AOTG in the S&P 500
25.4%FMED in the S&P 500
+22.3%AOTG total return, 1 year
+28.3%FMED total return, 1 year

ETFIQ Off-Index Score: FMED scores higher

How much of it is not the index it is sold as an alternative to?

AOTG 4.1FMED 40.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

AOTG23% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
77%23%of its weight in S&P 500 companiesoutside the S&P 500active share 69% · top ten 68% of the fund · 41 holdings filed May 29, 2026 · Nasdaq-100: 68% in77%23%in the S&P 500outsideactive share 69% · top ten 68% of the fund
FMED75% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
25%75%in the S&P 500of its weight outside the S&P 500active share 97% · top ten 32% of the fund · 68 holdings filed May 31, 2026 · Nasdaq-100: 9% in25%75%inoutside the S&P 500active share 97% · top ten 32% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, AOTG and FMED hold 0% of their money in the same securities at the same weight.

Positions AOTG and FMED both hold, largest shared weight first
HoldingAOTGFMED
Veeva Systems Inc0.24%1.79%
Only in each
Only in AOTGOnly in FMED
Advanced Micro Devices Inc 15.39%UCB SA 4.75%
NVIDIA Corp 10.47%LIFESTANCE HEALTH GROUP INC 4.29%
Micron Technology Inc 9.53%DANAHER CORP 3.43%
Taiwan Semiconductor Manufacturing Co Lt 6.78%10X GENOMICS INC 3.12%
AppLovin Corp 5.31%INTUITIVE SURGICAL INC 2.93%
Toast Inc 4.65%COGENT BIOSCIENCES INC 2.86%
Amazon.com Inc 4.40%ALNYLAM PHARMACEUTICALS INC 2.80%
Alphabet Inc 4.11%ARGENX SE 2.79%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 29, 2026 and May 31, 2026.

Performance, window by window

AOTG and FMED over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
AOTGFMEDAOTGFMEDAOTGFMED
3 months+2.7%+21.3%+0.4 pts+19.0 pts+5.2 pts+23.7 pts
6 months+37.5%+32.3%+19.5 pts+14.3 pts+13.3 pts+8.0 pts
1 year+22.3%+28.3%+5.8 pts+11.7 pts+0.6 pts+6.5 pts
3 years+120.6%+39.6%+42.2 pts−38.8 pts+22.4 pts−58.5 pts
Since launch+168.9%+25.8%+57.1 pts−57.6 pts+8.5 pts−78.1 pts
Open the live comparison on ETFIQ
AOTG and FMED on the same fields, as of Sep 18, 2026. Source: ETFIQ.
AOTG
AOT Growth and Innovation ETF
Holds 41 stocks in broad innovation and megatrends, 77% of its weight in S&P 500 companies
FMED
Fidelity Disruptive Medicine ETF
Holds 68 stocks in broad innovation and megatrends, 25% of its weight in S&P 500 companies
IssuerAOT InvestFidelity
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50077.4%25.4%
Active share vs the S&P 50069.1%97.1%
In the Nasdaq-10067.7%8.7%
Holdings4168
Top ten, share of the fund68.4%31.5%
Expense ratio0.75%0.50%
Fee for the differing part1.09%0.51%
Total return, 1 year+22.3%+28.3%
vs the S&P 500+5.8 pts+11.7 pts
vs the Nasdaq-100+0.6 pts+6.5 pts
Below its high−0.6%−3.8%
Net assets$105m$52m

AOTG in plain words

By weight, 77% of AOTG's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 69%. The top ten holdings are 68% of the fund across 41 positions, as filed for May 29, 2026. Over the year to Sep 18, 2026 the fund returned +22.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 5.8 pts.

FMED in plain words

By weight, 25% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 32% of the fund across 68 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +28.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 11.7 pts.

Questions people ask

Do AOTG and FMED hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, AOTG or FMED?
AOTG has 77% of its weight in S&P 500 names and FMED has 25%, so FMED differs more from the index.
Which is cheaper, AOTG or FMED?
AOTG charges 0.75% a year and FMED charges 0.50%, so FMED is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

AOTG against FMED, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, AOTG against FMED, data as of Sep 18, 2026. https://etfiq.com/compare/themes/aotg-vs-fmed Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources