Data as of Nov 4, 2026.

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Thematic ETFs

FMED vs HTEC: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, FMED returned +27.4% to HTEC's +43.7%; 21% of their weight is in the same names.

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Net assets: $52m on Sep 30, 2026 for Fidelity Disruptive Medicine ETF, and $69m on Jul 31, 2026 for ROBO Global Healthcare Technology and Innovation ETF.

At a glance
21.8%
FMED in the S&P 500
32.7%
HTEC in the S&P 500
+27.4%
FMED total return, 1 year
+43.7%
HTEC total return, 1 year
FMED · 1 year to Nov 4, 2026 78% of its weight is outside the S&P 500
78% of its weight is outside the S&P 50022% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.22%78%in the S&P 500of its weight outside the S&P 500active share 98% · top ten 33% of the fund · 72 holdings as filed for Aug 31, 2026 · Nasdaq-100: 5% in78% of its weight is outside the S&P 50022% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.22%78%inoutside the S&P 500active share 98% · Nasdaq-100: 5% in

22% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.

HTEC · 1 year to Nov 4, 2026 67% of its weight is outside the S&P 500
67% of its weight is outside the S&P 50033% of HTEC's weight is in S&P 500 companies and 67% is outside the index. Holdings as of Jul 31, 2026.33%67%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 98% · top ten 22% of the fund · 62 holdings as filed for Jul 31, 2026 · Nasdaq-100: 8% in67% of its weight is outside the S&P 50033% of HTEC's weight is in S&P 500 companies and 67% is outside the index. Holdings as of Jul 31, 2026.33%67%inoutside the S&P 500active share 98% · Nasdaq-100: 8% in

33% of HTEC's weight is in S&P 500 companies and 67% is outside the index. Holdings as of Jul 31, 2026.

Pair scorecard

FMED costs 0.18 points a year less; their one-year returns differ by 16.3 points.

FMED vs HTEC: Holdings Overlap & Returns
MeasureFMEDHTEC
Return
Total return, 1 year+27.4%+43.7%
Drawdown
Below its all-time high8.3%, high on Feb 12, 2021
Benchmark
What it tracksBroad innovation and megatrendsBroad innovation and megatrends
Cost and size
Expense ratio0.50%0.68%
Net assets, FMED as of Sep 30, 2026 and HTEC as of Jul 31, 2026$52m$69m
Holdings
Holdings in common21%

Method

What they share

21%

By the books each fund has filed, FMED and HTEC hold 21% of their money in the same securities at the same weight. Holdings dated Jul 31, 2026 and Aug 31, 2026.

0 half 100%

half

21% in common

Positions both hold · largest shared weight first FMED HTEC
NATERA INC 3.30% 2.23%
THERMO FISHER SCIENTIFIC INC 3.83% 2.18%
ILLUMINA INC 2.82% 2.08%
DANAHER CORP 3.73% 1.67%
EDWARDS LIFESCIENCES CORP 1.76% 1.55%
GUARDANT HEALTH INC 1.53% 2.31%
INTUITIVE SURGICAL INC 2.05% 1.50%
MODERNA INC 2.72% 1.48%
TWIST BIOSCIENCE CORP 1.35% 2.23%
VEEVA SYS INC 1.66% 1.22%
ALNYLAM PHARMACEUTICALS INC 2.33% 1.22%
BOSTON SCIENTIFIC CORP 1.14% 1.73%
Only in one fund ↓
Only in FMED
10X GENOMICS INC 5.19%
ARGENX SE 3.20%
LIFESTANCE HEALTH GROUP INC 3.00%
REVOLUTION MEDICINES INC 2.87%
HEARTFLOW INC 2.59%
SARTORIUS STEDIM BIOTECH 2.56%
COGENT BIOSCIENCES INC 2.31%
ASCENDIS PHARMA A/S 1.97%
Only in HTEC
CAREDX, INC. 2.68%
MEDPACE HOLDINGS, INC. 2.12%
ADAPTIVE BIOTECHNOLOGIES CORPORATION 2.11%
IQVIA HOLDINGS INC 2.10%
ARROWHEAD PHARMACEUTICALS, INC. 2.08%
REGENERON PHARMACEUTICALS, INC. 1.97%
GLAUKOS CORPORATION 1.92%
VERTEX PHARMACEUTICALS INCORPORATED 1.91%
Check overlap with more funds →

Window by window

Window by window: FMED vs HTEC: Holdings Overlap & Returns
Total return
WindowFMEDHTEC
3 months+14.9%+18.2%
6 months+31.2%+37.2%
1 year+27.4%+43.7%
3 years+57.8%+99.7%
Since launchNot the same days: FMED Jun 2023 · HTEC Jun 2019+31.7%+96.3%

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Side by side

FMED Fidelity Disruptive Medicine ETF · Holds 72 stocks in broad innovation and megatrends, 22% of its weight in S&P 500 companies HTEC ROBO Global Healthcare Technology and Innovation ETF · Holds 62 stocks in broad innovation and megatrends, 33% of its weight in S&P 500 companies
Theme Broad innovation and megatrends Broad innovation and megatrends
In the S&P 500 21.8% 32.7%
Active share vs the S&P 500 97.5% 97.9%
In the Nasdaq-100 5.1% 8.1%
Holdings 72 62
Top ten, share of the fund 33.2% 22.1%
Expense ratio 0.50% 0.68%
Fee for the differing part 0.51% 0.69%
Total return, 1 year +27.4% +43.7%
vs its benchmark not measured not measured
Below its high −0.9% −8.3%
Net assets, FMED as of Sep 30, 2026 and HTEC as of Jul 31, 2026 $52m $69m

As of Nov 4, 2026. Source: ETFIQ.

21% of the two portfolios are the same securities at the same weight.

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About each fund
FMED

By weight, 22% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 33% of the fund across 72 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned +27.4% with distributions reinvested.

HTEC

By weight, 33% of HTEC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 22% of the fund across 62 positions, as filed for Jul 31, 2026. Over the year to Nov 4, 2026 the fund returned +43.7% with distributions reinvested. It sits 8.3% below its all-time high of Feb 12, 2021.

Questions people ask

Do FMED and HTEC hold the same stocks?
By their latest filings, 21% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or HTEC?
FMED has 22% of its weight in S&P 500 names and HTEC has 33%, so HTEC differs more from the index.
Which is cheaper, FMED or HTEC?
FMED charges 0.50% a year and HTEC charges 0.68%, so FMED is cheaper. Fees come from each fund's prospectus.
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ETFIQ, FMED against HTEC, data as of Nov 4, 2026. https://etfiq.com/compare/themes/fmed-vs-htec

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