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Data as of .

FMED vs HTEC: which is really different?

FMED and HTEC hold 22% of their weight in the same names, and HTEC returned more over the year.

Fidelity Disruptive Medicine ETF and ROBO Global(R) Healthcare Technology and Innovation ETF.

25.4%FMED in the S&P 500
31.8%HTEC in the S&P 500
+28.3%FMED total return, 1 year
+37.8%HTEC total return, 1 year

ETFIQ Off-Index Score: HTEC scores higher

How much of it is not the index it is sold as an alternative to?

FMED 40.1HTEC 480.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

FMED75% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
25%75%in the S&P 500of its weight outside the S&P 500active share 97% · top ten 32% of the fund · 68 holdings filed May 31, 2026 · Nasdaq-100: 9% in25%75%inoutside the S&P 500active share 97% · top ten 32% of the fund
HTEC68% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
32%68%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 98% · top ten 23% of the fund · 59 holdings filed Apr 30, 2026 · Nasdaq-100: 9% in32%68%inoutside the S&P 500active share 98% · top ten 23% of the fund

22% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, FMED and HTEC hold 22% of their money in the same securities at the same weight.

Positions FMED and HTEC both hold, largest shared weight first
HoldingFMEDHTEC
ALNYLAM PHARMACEUTICALS INC2.80%2.02%
INTUITIVE SURGICAL INC2.93%1.95%
DANAHER CORP3.43%1.68%
VERACYTE INC1.54%1.65%
THERMO FISHER SCIENTIFIC INC1.54%1.99%
BOSTON SCIENTIFIC CORP1.44%1.69%
NATERA INC1.43%2.17%
GUARDANT HEALTH INC1.39%2.00%
STRYKER CORP1.37%1.81%
MODERNA INC2.11%1.31%
LONZA GROUP AG1.22%1.80%
IRHYTHM TECHNOLOGIES INC0.97%1.78%
Only in each
Only in FMEDOnly in HTEC
UCB SA 4.75%AxoGen, Inc. 3.16%
LIFESTANCE HEALTH GROUP INC 4.29%ARROWHEAD PHARMACEUTICALS, INC. 2.57%
10X GENOMICS INC 3.12%Twist Bioscience Corp 2.34%
COGENT BIOSCIENCES INC 2.86%GLAUKOS CORPORATION 2.23%
ARGENX SE 2.79%TEMPUS AI, INC. 2.13%
LEGEND BIOTECH CORP 2.30%NOVOCURE LIMITED 2.05%
UNITEDHEALTH GROUP INC 2.26%ILLUMINA, INC. 1.96%
BIO TECHNE CORP 2.25%VERTEX PHARMACEUTICALS INCORPORATED 1.96%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and May 31, 2026.

Performance, window by window

FMED and HTEC over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
FMEDHTECFMEDHTECFMEDHTEC
3 months+21.3%+20.9%+19.0 pts+18.7 pts+23.7 pts+23.4 pts
6 months+32.3%+32.1%+14.3 pts+14.1 pts+8.0 pts+7.9 pts
1 year+28.3%+37.8%+11.7 pts+21.3 pts+6.5 pts+16.1 pts
3 years+39.6%+63.1%−38.8 pts−15.3 pts−58.5 pts−35.0 pts
Since launch+25.8%+76.8%−57.6 pts−114.2 pts−78.1 pts−230.7 pts
Open the live comparison on ETFIQ
FMED and HTEC on the same fields, as of Sep 18, 2026. Source: ETFIQ.
FMED
Fidelity Disruptive Medicine ETF
Holds 68 stocks in broad innovation and megatrends, 25% of its weight in S&P 500 companies
HTEC
ROBO Global(R) Healthcare Technology and Innovation ETF
Holds 59 stocks in broad innovation and megatrends, 32% of its weight in S&P 500 companies
IssuerFidelityROBO Global
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50025.4%31.8%
Active share vs the S&P 50097.1%97.9%
In the Nasdaq-1008.7%9.1%
Holdings6859
Top ten, share of the fund31.5%22.7%
Expense ratio0.50%0.68%
Fee for the differing part0.51%0.69%
Total return, 1 year+28.3%+37.8%
vs the S&P 500+11.7 pts+21.3 pts
vs the Nasdaq-100+6.5 pts+16.1 pts
Below its high−3.8%−17.4%
Net assets$52m$53m

FMED in plain words

By weight, 25% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 32% of the fund across 68 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +28.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 11.7 pts.

HTEC in plain words

By weight, 32% of HTEC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 23% of the fund across 59 positions, as filed for Apr 30, 2026. Over the year to Sep 18, 2026 the fund returned +37.8% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 21.2 pts. It sits 17.4% below its all-time high of Feb 12, 2021.

Questions people ask

Do FMED and HTEC hold the same stocks?
By their latest filings, 22% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or HTEC?
FMED has 25% of its weight in S&P 500 names and HTEC has 32%, so HTEC differs more from the index.
Which is cheaper, FMED or HTEC?
FMED charges 0.50% a year and HTEC charges 0.68%, so FMED is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

FMED against HTEC, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, FMED against HTEC, data as of Sep 18, 2026. https://etfiq.com/compare/themes/fmed-vs-htec Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources