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Data as of .

AOTG vs LFSC: which is really different?

AOTG and LFSC hold 0% of their weight in the same names, and LFSC returned more over the year.

AOT Growth and Innovation ETF and F/m Emerald Life Sciences Innovation ETF.

77.4%AOTG in the S&P 500
0.0%LFSC in the S&P 500
+22.3%AOTG total return, 1 year
+53.0%LFSC total return, 1 year

ETFIQ Off-Index Score: LFSC scores higher

How much of it is not the index it is sold as an alternative to?

AOTG 4.1LFSC 91.80.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

AOTG23% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
77%23%of its weight in S&P 500 companiesoutside the S&P 500active share 69% · top ten 68% of the fund · 41 holdings filed May 29, 2026 · Nasdaq-100: 68% in77%23%in the S&P 500outsideactive share 69% · top ten 68% of the fund
LFSC100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund · 39 holdings filed May 31, 2026 · Nasdaq-100: 1% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, AOTG and LFSC hold 0% of their money in the same securities at the same weight.

Only in each
Only in AOTGOnly in LFSC
Advanced Micro Devices Inc 15.39%Travere Therapeutics Inc 7.66%
NVIDIA Corp 10.47%Cogent Biosciences Inc 7.52%
Micron Technology Inc 9.53%LivaNova PLC 7.11%
Taiwan Semiconductor Manufacturing Co Lt 6.78%Spyre Therapeutics Inc 6.41%
AppLovin Corp 5.31%Guardant Health Inc 5.51%
Toast Inc 4.65%Mirum Pharmaceuticals Inc 4.92%
Amazon.com Inc 4.40%Corcept Therapeutics Inc 4.79%
Alphabet Inc 4.11%United Therapeutics Corp 4.15%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 29, 2026 and May 31, 2026.

Performance, window by window

AOTG and LFSC over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
AOTGLFSCAOTGLFSCAOTGLFSC
3 months+2.7%+8.7%+0.4 pts+6.5 pts+5.2 pts+11.2 pts
6 months+37.5%+36.0%+19.5 pts+17.9 pts+13.3 pts+11.7 pts
1 year+22.3%+53.0%+5.8 pts+36.5 pts+0.6 pts+31.3 pts
3 years+120.6%not published+42.2 ptsnot published+22.4 ptsnot published
Since launch+168.9%+81.3%+57.1 pts+44.3 pts+8.5 pts+30.9 pts
Open the live comparison on ETFIQ
AOTG and LFSC on the same fields, as of Sep 18, 2026. Source: ETFIQ.
AOTG
AOT Growth and Innovation ETF
Holds 41 stocks in broad innovation and megatrends, 77% of its weight in S&P 500 companies
LFSC
F/m Emerald Life Sciences Innovation ETF
Holds 39 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
IssuerAOT InvestF/m
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50077.4%0.0%
Active share vs the S&P 50069.1%100.0%
In the Nasdaq-10067.7%0.6%
Holdings4139
Top ten, share of the fund68.4%54.7%
Expense ratio0.75%0.54%
Fee for the differing part1.09%0.54%
Total return, 1 year+22.3%+53.0%
vs the S&P 500+5.8 pts+36.5 pts
vs the Nasdaq-100+0.6 pts+31.3 pts
Below its high−0.6%−6.8%
Net assets$105m$105m

AOTG in plain words

By weight, 77% of AOTG's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 69%. The top ten holdings are 68% of the fund across 41 positions, as filed for May 29, 2026. Over the year to Sep 18, 2026 the fund returned +22.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 5.8 pts.

LFSC in plain words

By weight, 0% of LFSC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 55% of the fund across 39 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +53.0% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 36.5 pts. It sits 6.8% below its all-time high of Aug 19, 2026.

Questions people ask

Do AOTG and LFSC hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, AOTG or LFSC?
AOTG has 77% of its weight in S&P 500 names and LFSC has 0%, so LFSC differs more from the index.
Which is cheaper, AOTG or LFSC?
AOTG charges 0.75% a year and LFSC charges 0.54%, so LFSC is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

AOTG against LFSC, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, AOTG against LFSC, data as of Sep 18, 2026. https://etfiq.com/compare/themes/aotg-vs-lfsc Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources