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Data as of .

LFSC vs QQQJ: which is really different?

LFSC and QQQJ hold 3% of their weight in the same names, and LFSC returned more over the year.

F/m Emerald Life Sciences Innovation ETF and Invesco NASDAQ Next Gen 100 ETF.

0.0%LFSC in the S&P 500
46.2%QQQJ in the S&P 500
+53.0%LFSC total return, 1 year
+22.4%QQQJ total return, 1 year

ETFIQ Off-Index Score: LFSC scores higher

How much of it is not the index it is sold as an alternative to?

LFSC 91.8QQQJ 56.60.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

LFSC100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund · 39 holdings filed May 31, 2026 · Nasdaq-100: 1% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund
QQQJ54% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
46%54%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 20% of the fund · 108 holdings filed Sep 19, 2026 · Nasdaq-100: 1% in46%54%in the S&P 500outside the S&P 500active share 99% · top ten 20% of the fund

3% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, LFSC and QQQJ hold 3% of their money in the same securities at the same weight.

Positions LFSC and QQQJ both hold, largest shared weight first
HoldingLFSCQQQJ
Guardant Health Inc5.51%1.20%
United Therapeutics Corp4.15%1.06%
Bridgebio Pharma Inc1.17%0.66%
Only in each
Only in LFSCOnly in QQQJ
Travere Therapeutics Inc 7.66%Natera Inc 2.67%
Cogent Biosciences Inc 7.52%eBay Inc 2.51%
LivaNova PLC 7.11%Revolution Medicines Inc 2.05%
Spyre Therapeutics Inc 6.41%Flex Ltd 2.01%
Mirum Pharmaceuticals Inc 4.92%NetApp Inc 1.97%
Corcept Therapeutics Inc 4.79%Illumina Inc 1.83%
VeraDermics Inc 3.42%United Airlines Holdings Inc 1.78%
Savara Inc 3.22%Elbit Systems Ltd 1.75%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 19, 2026.

Performance, window by window

LFSC and QQQJ over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
LFSCQQQJLFSCQQQJLFSCQQQJ
3 months+8.7%−0.9%+6.5 pts−3.1 pts+11.2 pts+1.6 pts
6 months+36.0%+22.6%+17.9 pts+4.6 pts+11.7 pts−1.6 pts
1 year+53.0%+22.4%+36.5 pts+5.8 pts+31.3 pts+0.7 pts
3 yearsnot published+80.4%not published+2.0 ptsnot published−17.8 pts
Since launch+81.3%+72.2%+44.3 pts−63.7 pts+30.9 pts−81.2 pts
Open the live comparison on ETFIQ
LFSC and QQQJ on the same fields, as of Sep 18, 2026. Source: ETFIQ.
LFSC
F/m Emerald Life Sciences Innovation ETF
Holds 39 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
QQQJ
Invesco NASDAQ Next Gen 100 ETF
Holds 108 stocks in broad innovation and megatrends, 46% of its weight in S&P 500 companies
IssuerF/mInvesco
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 5000.0%46.2%
Active share vs the S&P 500100.0%98.6%
In the Nasdaq-1000.6%1.4%
Holdings39108
Top ten, share of the fund54.7%19.9%
Expense ratio0.54%0.15%
Fee for the differing part0.54%0.15%
Total return, 1 year+53.0%+22.4%
vs the S&P 500+36.5 pts+5.8 pts
vs the Nasdaq-100+31.3 pts+0.7 pts
Below its high−6.8%−5.5%
Net assets$105m$1.2bn

LFSC in plain words

By weight, 0% of LFSC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 55% of the fund across 39 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +53.0% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 36.5 pts. It sits 6.8% below its all-time high of Aug 19, 2026.

QQQJ in plain words

By weight, 46% of QQQJ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 20% of the fund across 108 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +22.4% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 5.8 pts. It sits 5.5% below its all-time high of Aug 13, 2026.

Questions people ask

Do LFSC and QQQJ hold the same stocks?
By their latest filings, 3% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, LFSC or QQQJ?
LFSC has 0% of its weight in S&P 500 names and QQQJ has 46%, so LFSC differs more from the index.
Which is cheaper, LFSC or QQQJ?
LFSC charges 0.54% a year and QQQJ charges 0.15%, so QQQJ is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

LFSC against QQQJ, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, LFSC against QQQJ, data as of Sep 18, 2026. https://etfiq.com/compare/themes/lfsc-vs-qqqj Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources