Data as of Oct 28, 2026.

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Across categories

IBB vs XLRE: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to XLRE's +4.3%, and XLRE charges 0.08% to IBB's 0.44%.

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Net assets on Oct 27, 2026: $11.0bn for iShares Biotechnology ETF and $8.0bn for State Street Real Estate Select Sector SPDR ETF.

At a glance
+37.5%
IBB total return, 1 year
+4.3%
XLRE total return, 1 year
0.44%
IBB expense ratio
0.08%
XLRE expense ratio

Pair scorecard

XLRE costs 0.36 points a year less; their one-year returns differ by 33.2 points; IBB is 1.4 times larger.

IBB vs XLRE: Differences, Returns & Fees
MeasureIBBXLRE
Return
Total return, 1 year+37.5%+4.3%
Drawdown
Below its high7.7%, high on Jul 28, 2026
Benchmark
What it tracksBiotechReal Estate Select Sector Index
Cost and size
Expense ratio0.44%0.08%
Net assets, as of Oct 27, 2026$11.0bn$8.0bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%58.9%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and XLRE hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB XLRE
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in XLRE
WELLTOWER INC 11.14%
PROLOGIS INC 8.19%
EQUINIX INC 6.72%
AMERICAN TOWER CORP 5.84%
PUBLIC STORAGE 4.87%
SIMON PROPERTY GROUP INC 4.76%
VIVMARK RESIDENTIAL 4.42%
DIGITAL REALTY TRUST INC 4.34%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF XLRE State Street Real Estate Select Sector SPDR ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Real estate
Total return, 1 year +37.5% +4.3%
Expense ratio 0.44% 0.08%
Already in the S&P 500 40.2% 99.5%
Holdings 245 31
Net assets, as of Oct 27, 2026 $11.0bn $8.0bn

IBB and XLRE on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

XLRE

XLRE tracks an index of Real estate. Over the year to Oct 28, 2026 it returned +4.3% with distributions reinvested. The prospectus expense ratio is 0.08% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 31 positions, with the top ten at 58.9%. It sat 7.7% below its high of Jul 28, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and XLRE in the same category?
IBB is a thematic ETF and XLRE is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or XLRE?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and XLRE +4.3%.
Which is cheaper, IBB or XLRE?
XLRE is cheaper, by 0.36 percentage points a year. That is about $36 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and XLRE overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 100% of XLRE by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against XLRE, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-xlre

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