Data as of Oct 28, 2026.

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IBB vs VNQ: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VNQ's +4.8%, and VNQ charges 0.13% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $35.9bn on Sep 30, 2026 for Vanguard Real Estate ETF.

At a glance
+37.5%
IBB total return, 1 year
+4.8%
VNQ total return, 1 year
0.44%
IBB expense ratio
0.13%
VNQ expense ratio

Pair scorecard

VNQ costs 0.31 points a year less; their one-year returns differ by 32.7 points; VNQ is 3.2 times larger.

IBB vs VNQ: Differences, Returns & Fees
MeasureIBBVNQ
Return
Total return, 1 year+37.5%+4.8%
Drawdown
Below its high8.3%, high on Jul 28, 2026
Benchmark
What it tracksBiotechMSCI US Investable Market Real Estate 25/50 Index
Cost and size
Expense ratio0.44%0.13%
Net assets, as of Sep 30, 2026$11.2bn$35.9bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%55.8%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

Risk and return

Oct 8, 2004 to Oct 23, 2026 · 1,150 weekly returns
IBB VNQ
Return
Total return edge IBB +852.1% +364.5%
Annualized edge IBB +10.7% +7.2%
Price return edge IBB +811.4% +80.5%
Risk
Volatility edge IBB 22.4% 25.0%
Max drawdown edge IBB −37.5% −72.5%
Risk-adjusted
Sharpe edge IBB 0.49 0.33
Sortino edge IBB 0.70 0.48
Calmar edge IBB 0.29 0.10
Reading

IBB returned more: +852.1% to +364.5%. IBB swung less: 22.4% to 25.0%. IBB fell less at its worst: −37.5% to −72.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: IBB vs VNQ: Differences, Returns & Fees
MeasureIBBVNQEdgeHow it is measured
Return
Total return+852.1%+364.5%IBBPrice change plus distributions, reinvested.
Annualized+10.7%+7.2%IBBTotal return as a yearly rate.
Price return+811.4%+80.5%IBBPrice change alone, distributions left out.
Risk
Volatility22.4%25.0%IBBSpread of weekly returns, annualized. Lower is steadier.
Downside deviation15.6%17.3%IBB (slight)Like volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.5%−72.5%IBBDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.490.33IBBReturn above Treasury bills per unit of volatility.
Sortino0.700.48IBBReturn above Treasury bills per unit of downside deviation.
Calmar0.290.10IBBAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,150 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

0%

By the books each fund has filed, IBB and VNQ hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB VNQ
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in VNQ
Vanguard Real Estate II Index Fund 14.51%
Welltower Inc 9.12%
Prologis Inc 6.86%
Equinix Inc 5.65%
American Tower Corp 4.32%
Simon Property Group Inc 3.69%
Digital Realty Trust Inc 3.68%
Realty Income Corp 2.85%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VNQ Vanguard Real Estate ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of US real estate
Total return, 1 year +37.5% +4.8%
Expense ratio 0.44% 0.13%
Already in the S&P 500 40.2% 62.8%
Holdings 245 141
Net assets, IBB as of Oct 27, 2026 and VNQ as of Sep 30, 2026 $11.0bn $35.9bn

IBB and VNQ on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-5288A7ACBB

IBB and VNQ do different jobs. What does each one do in a portfolio?

  1. What each follows. IBB follows Biotech and VNQ follows MSCI US Investable Market Real Estate 25/50 Index.
  2. Holdings in common. 0% of the weight is in the same securities (holdings dated Oct 27, 2026 and Sep 30, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 IBB returned +37.5% and VNQ +4.8% with distributions reinvested, a gap of 32.7 points.

Data as of Oct 28, 2026.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VNQ

VNQ tracks an index of US real estate. Over the year to Oct 28, 2026 it returned +4.8% with distributions reinvested. The prospectus expense ratio is 0.13% a year. By its holdings published by its issuer as of Sep 30, 2026, 63% of the fund by weight is stocks the S&P 500 also holds, across 141 positions, with the top ten at 55.8%. It sat 8.3% below its high of Jul 28, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and VNQ in the same category?
IBB is a thematic ETF and VNQ is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VNQ?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VNQ +4.8%.
Which is cheaper, IBB or VNQ?
VNQ is cheaper, by 0.31 percentage points a year. That is about $31 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VNQ overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 63% of VNQ by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against VNQ, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vnq

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