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Data as of .

ILDR vs LFSC: which is really different?

ILDR and LFSC hold 2% of their weight in the same names, and LFSC returned more over the year.

First Trust Innovation Leaders ETF and F/m Emerald Life Sciences Innovation ETF.

65.8%ILDR in the S&P 500
0.0%LFSC in the S&P 500
+19.9%ILDR total return, 1 year
+53.0%LFSC total return, 1 year

ETFIQ Off-Index Score: LFSC scores higher

How much of it is not the index it is sold as an alternative to?

ILDR 2.9LFSC 91.80.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

ILDR34% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
66%34%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 67% · top ten 44% of the fund · 82 holdings filed Sep 18, 2026 · Nasdaq-100: 49% in66%34%in the S&P 500outsideactive share 67% · top ten 44% of the fund
LFSC100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund · 39 holdings filed May 31, 2026 · Nasdaq-100: 1% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund

2% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, ILDR and LFSC hold 2% of their money in the same securities at the same weight.

Positions ILDR and LFSC both hold, largest shared weight first
HoldingILDRLFSC
Mirum Pharmaceuticals, Inc.0.90%4.92%
BridgeBio Pharma, Inc.0.83%1.17%
Viridian Therapeutics, Inc.0.47%2.23%
Only in each
Only in ILDROnly in LFSC
NVIDIA Corporation 9.78%Travere Therapeutics Inc 7.66%
Advanced Micro Devices, Inc. 5.79%Cogent Biosciences Inc 7.52%
Amazon.com, Inc. 5.79%LivaNova PLC 7.11%
Alphabet Inc. (Class A) 4.81%Spyre Therapeutics Inc 6.41%
Broadcom Inc. 3.57%Guardant Health Inc 5.51%
Marvell Technology, Inc. 3.13%Corcept Therapeutics Inc 4.79%
Eli Lilly and Company 3.02%United Therapeutics Corp 4.15%
Micron Technology, Inc. 2.80%VeraDermics Inc 3.42%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 18, 2026.

Performance, window by window

ILDR and LFSC over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
ILDRLFSCILDRLFSCILDRLFSC
3 months+0.3%+8.7%−1.9 pts+6.5 pts+2.8 pts+11.2 pts
6 months+31.0%+36.0%+12.9 pts+17.9 pts+6.7 pts+11.7 pts
1 year+19.9%+53.0%+3.3 pts+36.5 pts−1.9 pts+31.3 pts
3 years+120.9%not published+42.5 ptsnot published+22.7 ptsnot published
Since launch+92.7%+81.3%−3.0 pts+44.3 pts−30.0 pts+30.9 pts
Open the live comparison on ETFIQ
ILDR and LFSC on the same fields, as of Sep 18, 2026. Source: ETFIQ.
ILDR
First Trust Innovation Leaders ETF
Holds 82 stocks in broad innovation and megatrends, 66% of its weight in S&P 500 companies
LFSC
F/m Emerald Life Sciences Innovation ETF
Holds 39 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
IssuerFirst TrustF/m
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50065.8%0.0%
Active share vs the S&P 50067.1%100.0%
In the Nasdaq-10049.0%0.6%
Holdings8239
Top ten, share of the fund44.1%54.7%
Expense ratio0.75%0.54%
Fee for the differing part1.12%0.54%
Total return, 1 year+19.9%+53.0%
vs the S&P 500+3.3 pts+36.5 pts
vs the Nasdaq-100−1.9 pts+31.3 pts
Below its high−3.5%−6.8%
Net assets$342m$105m

ILDR in plain words

By weight, 66% of ILDR's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 67%. The top ten holdings are 44% of the fund across 82 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +19.9% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 3.3 pts.

LFSC in plain words

By weight, 0% of LFSC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 55% of the fund across 39 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +53.0% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 36.5 pts. It sits 6.8% below its all-time high of Aug 19, 2026.

Questions people ask

Do ILDR and LFSC hold the same stocks?
By their latest filings, 2% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, ILDR or LFSC?
ILDR has 66% of its weight in S&P 500 names and LFSC has 0%, so LFSC differs more from the index.
Which is cheaper, ILDR or LFSC?
ILDR charges 0.75% a year and LFSC charges 0.54%, so LFSC is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

ILDR against LFSC, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, ILDR against LFSC, data as of Sep 18, 2026. https://etfiq.com/compare/themes/ildr-vs-lfsc Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources