Do FMED and GXDW hold the same stocks?

By their latest filings, 0% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, FMED or GXDW?

FMED has 22% of its weight in S&P 500 names and GXDW has 0%, so GXDW differs more from the index.

Which is cheaper, FMED or GXDW?

FMED and GXDW both charge 0.50% a year, so neither is cheaper. Fees come from each fund's prospectus.

Data as of Nov 4, 2026.

Thematic ETFs

FMED vs GXDW: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, FMED returned +27.4% to GXDW's −13.8%; 0% of their weight is in the same names.

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Net assets: $52m on Sep 30, 2026 for Fidelity Disruptive Medicine ETF, and $6.0m on Oct 12, 2026 for Global X Dorsey Wright Thematic ETF.

FMED on its own →GXDW on its own →

At a glance

21.8%

FMED in the S&P 500

0.0%

GXDW in the S&P 500

+27.4%

FMED total return, 1 year

−13.8%

GXDW total return, 1 year

FMED · 1 year to Nov 4, 2026 78% of its weight is outside the S&P 500

22% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.

GXDW · 1 year to Nov 4, 2026 100% of its weight is outside the S&P 500

0% of GXDW's weight is in S&P 500 companies and 100% is outside the index. Holdings as of Aug 31, 2026.

Pair scorecard

Both cost 0.50% a year; their one-year returns differ by 41.2 points.

FMED vs GXDW: Holdings Overlap & Returns
Measure	FMED	GXDW
Return
Measure	FMED	GXDW
Total return, 1 year	+27.4%	−13.8%
Drawdown
Measure	FMED	GXDW
Below its all-time high		61.7%, high on Feb 10, 2021
Benchmark
Measure	FMED	GXDW
What it tracks	Broad innovation and megatrends	Broad innovation and megatrends
Cost and size
Measure	FMED	GXDW
Expense ratio	0.50%	0.50%
Net assets, FMED as of Sep 30, 2026 and GXDW as of Oct 12, 2026	$52m	$6.0m
Holdings
Measure	FMED	GXDW
Holdings in common	0%

Method

What they share

By the books each fund has filed, FMED and GXDW hold 0% of their money in the same securities at the same weight. Holdings dated Aug 31, 2026.

50%

0 half 100%

half

0% in common

Positions both hold · largest shared weight first FMED GXDW

Only in one fund ↓

Only in FMED

10X GENOMICS INC 5.19%

THERMO FISHER SCIENTIFIC INC 3.83%

DANAHER CORP 3.73%

NATERA INC 3.30%

ARGENX SE 3.20%

LIFESTANCE HEALTH GROUP INC 3.00%

REVOLUTION MEDICINES INC 2.87%

ILLUMINA INC 2.82%

Only in GXDW

Global X Cybersecurity ETF 21.19%

Global X Lithium & Battery Tech ETF 20.36%

Global X Artificial Intelligence & Technology ETF 20.15%

Global X Hydrogen ETF 19.58%

Global X Internet of Things ETF 18.70%

Check overlap with more funds →

Window by window

Window by window: FMED vs GXDW: Holdings Overlap & Returns
	Total return
Window	FMED	GXDW
3 months	+14.9%	−4.0%
6 months	+31.2%	−20.3%
1 year	+27.4%	−13.8%
3 years	+57.8%	+7.4%
Since launchNot the same days: FMED Jun 2023 · GXDW Nov 2019	+31.7%	−3.6%

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Side by side

FMED Fidelity Disruptive Medicine ETF · Holds 72 stocks in broad innovation and megatrends, 22% of its weight in S&P 500 companies GXDW Global X Dorsey Wright Thematic ETF · Holds 5 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies

Issuer Fidelity Global X

Theme Broad innovation and megatrends Broad innovation and megatrends

In the S&P 500 21.8% 0.0%

Active share vs the S&P 500 97.5% 100.0%

In the Nasdaq-100 5.1% 0.0%

Holdings 72 5

Top ten, share of the fund 33.2% 100.0%

Expense ratio 0.50% 0.50%

Fee for the differing part 0.51% 0.50%

Total return, 1 year +27.4% −13.8%

vs its benchmark not measured not measured

Below its high −0.9% −61.7%

Net assets, FMED as of Sep 30, 2026 and GXDW as of Oct 12, 2026 $52m $6.0m

As of Nov 4, 2026. Source: ETFIQ.

0% of the two portfolios are the same securities at the same weight.

Alert

About each fund

FMED

By weight, 22% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 33% of the fund across 72 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned +27.4% with distributions reinvested.

GXDW

By weight, 0% of GXDW's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 100% of the fund across 5 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned −13.8% with distributions reinvested. It sits 61.7% below its all-time high of Feb 10, 2021.

Questions people ask

Do FMED and GXDW hold the same stocks?: By their latest filings, 0% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or GXDW?: FMED has 22% of its weight in S&P 500 names and GXDW has 0%, so GXDW differs more from the index.
Which is cheaper, FMED or GXDW?: FMED and GXDW both charge 0.50% a year, so neither is cheaper. Fees come from each fund's prospectus.

Other comparisons

FMED vs BULD FMED vs ABOT FMED vs INVN FMED vs XDAT GXDW vs INVN GXDW vs ABOT GXDW vs THMZ GXDW vs TEKY

Where to next

All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →FMED on its own →GXDW on its own →FMED dividend history →FMED holdings →GXDW dividend history →GXDW holdings →Method →Standards and sources →

Sources and dates

FMED filings on SEC EDGAR ↗

FMED prospectus with the expense ratio (SEC) ↗

Fidelity website ↗

GXDW filings on SEC EDGAR ↗

GXDW prospectus with the expense ratio (SEC) ↗

Global X page for GXDW ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, FMED against GXDW, data as of Nov 4, 2026. https://etfiq.com/compare/themes/fmed-vs-gxdw

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.