Get the weekly note
ETFIQetfiq.com · independent ETF data

Data as of .

FMED vs GXDW: which is really different?

FMED and GXDW hold 0% of their weight in the same names, and FMED returned more over the year.

Fidelity Disruptive Medicine ETF and Global X Dorsey Wright Thematic ETF.

25.4%FMED in the S&P 500
0.0%GXDW in the S&P 500
+28.3%FMED total return, 1 year
−10.2%GXDW total return, 1 year

ETFIQ Off-Index Score: GXDW scores higher

How much of it is not the index it is sold as an alternative to?

FMED 40.1GXDW 91.80.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

FMED75% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
25%75%in the S&P 500of its weight outside the S&P 500active share 97% · top ten 32% of the fund · 68 holdings filed May 31, 2026 · Nasdaq-100: 9% in25%75%inoutside the S&P 500active share 97% · top ten 32% of the fund
GXDW100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 100% of the fund · 7 holdings filed Sep 18, 2026 · Nasdaq-100: 0% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 100% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, FMED and GXDW hold 0% of their money in the same securities at the same weight.

Only in each
Only in FMEDOnly in GXDW
UCB SA 4.75%GLOBAL X HYDROGEN ETF 20.93%
LIFESTANCE HEALTH GROUP INC 4.29%GLOBAL X GENOMICS & BIOTECHN 20.55%
DANAHER CORP 3.43%GLOBAL X CYBERSECURITY ETF 20.21%
10X GENOMICS INC 3.12%GLOBAL X ART INTEL & TECH 19.89%
INTUITIVE SURGICAL INC 2.93%GLOBAL X LITHIUM & BATTERY T 18.41%
COGENT BIOSCIENCES INC 2.86%OTHER PAYABLE & RECEIVABLES 0.01%
ALNYLAM PHARMACEUTICALS INC 2.80%CASH -0.01%
ARGENX SE 2.79%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 18, 2026.

Performance, window by window

FMED and GXDW over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
FMEDGXDWFMEDGXDWFMEDGXDW
3 months+21.3%−13.3%+19.0 pts−15.5 pts+23.7 pts−10.8 pts
6 months+32.3%+10.8%+14.3 pts−7.2 pts+8.0 pts−13.4 pts
1 year+28.3%−10.2%+11.7 pts−26.8 pts+6.5 pts−32.0 pts
3 years+39.6%+3.7%−38.8 pts−74.7 pts−58.5 pts−94.5 pts
Since launch+25.8%+2.3%−57.6 pts−171.8 pts−78.1 pts−273.6 pts
Open the live comparison on ETFIQ
FMED and GXDW on the same fields, as of Sep 18, 2026. Source: ETFIQ.
FMED
Fidelity Disruptive Medicine ETF
Holds 68 stocks in broad innovation and megatrends, 25% of its weight in S&P 500 companies
GXDW
Global X Dorsey Wright Thematic ETF
Holds 7 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
IssuerFidelityGlobal X
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50025.4%0.0%
Active share vs the S&P 50097.1%100.0%
In the Nasdaq-1008.7%0.0%
Holdings687
Top ten, share of the fund31.5%100.0%
Expense ratio0.50%0.50%
Fee for the differing part0.51%0.50%
Total return, 1 year+28.3%−10.2%
vs the S&P 500+11.7 pts−26.8 pts
vs the Nasdaq-100+6.5 pts−32.0 pts
Below its high−3.8%−59.4%
Net assets$52m$6m

FMED in plain words

By weight, 25% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 32% of the fund across 68 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +28.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 11.7 pts.

GXDW in plain words

By weight, 0% of GXDW's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 100% of the fund across 7 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned −10.2% with distributions reinvested against +16.6% for the S&P 500, so a holder was behind by 26.8 pts. It sits 59.4% below its all-time high of Feb 10, 2021.

Questions people ask

Do FMED and GXDW hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or GXDW?
FMED has 25% of its weight in S&P 500 names and GXDW has 0%, so GXDW differs more from the index.
Which is cheaper, FMED or GXDW?
FMED charges 0.50% a year and GXDW charges 0.50%, so FMED is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

FMED against GXDW, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, FMED against GXDW, data as of Sep 18, 2026. https://etfiq.com/compare/themes/fmed-vs-gxdw Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources