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Data as of .

FMED vs GDOC: which is really different?

FMED and GDOC hold 24% of their weight in the same names, and FMED returned more over the year.

Fidelity Disruptive Medicine ETF and Goldman Sachs Future Health Care Equity ETF.

25.4%FMED in the S&P 500
56.7%GDOC in the S&P 500
+28.3%FMED total return, 1 year
+13.9%GDOC total return, 1 year

ETFIQ Off-Index Score: FMED scores higher

How much of it is not the index it is sold as an alternative to?

FMED 40.1GDOC 33.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

FMED75% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
25%75%in the S&P 500of its weight outside the S&P 500active share 97% · top ten 32% of the fund · 68 holdings filed May 31, 2026 · Nasdaq-100: 9% in25%75%inoutside the S&P 500active share 97% · top ten 32% of the fund
GDOC43% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
57%43%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 95% · top ten 58% of the fund · 41 holdings filed May 31, 2026 · Nasdaq-100: 9% in57%43%in the S&P 500outsideactive share 95% · top ten 58% of the fund

24% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, FMED and GDOC hold 24% of their money in the same securities at the same weight.

Positions FMED and GDOC both hold, largest shared weight first
HoldingFMEDGDOC
INTUITIVE SURGICAL INC2.93%3.96%
ARGENX SE2.79%4.13%
EDWARDS LIFESCIENCES CORP2.12%3.03%
THERMO FISHER SCIENTIFIC INC1.54%4.59%
BOSTON SCIENTIFIC CORP1.44%3.84%
CYTOKINETICS INC1.55%1.42%
GUARDANT HEALTH INC1.39%5.42%
XENON PHARMACEUTICALS INC1.92%1.38%
UNITEDHEALTH GROUP INC2.26%1.37%
LONZA GROUP AG1.22%2.84%
DEXCOM INC1.18%2.84%
INSMED INC1.80%1.12%
Only in each
Only in FMEDOnly in GDOC
UCB SA 4.75%JOHNSON & JOHNSON 8.19%
LIFESTANCE HEALTH GROUP INC 4.29%MERCK & COMPANY INC 6.04%
DANAHER CORP 3.43%ASTRAZENECA PLC 4.92%
10X GENOMICS INC 3.12%HOYA CORP 3.58%
COGENT BIOSCIENCES INC 2.86%AGILENT TECHNOLOGIES INC 2.81%
ALNYLAM PHARMACEUTICALS INC 2.80%CENCORA INC 2.38%
LEGEND BIOTECH CORP 2.30%APOGEE THERAPEUTICS INC 2.00%
BIO TECHNE CORP 2.25%ROYALTY PHARMA PLC 1.79%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026.

Performance, window by window

FMED and GDOC over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
FMEDGDOCFMEDGDOCFMEDGDOC
3 months+21.3%+11.7%+19.0 pts+9.5 pts+23.7 pts+14.2 pts
6 months+32.3%+16.6%+14.3 pts−1.4 pts+8.0 pts−7.6 pts
1 year+28.3%+13.9%+11.7 pts−2.6 pts+6.5 pts−7.8 pts
3 years+39.6%+19.5%−38.8 pts−58.9 pts−58.5 pts−78.7 pts
Since launch+25.8%−4.3%−57.6 pts−79.9 pts−78.1 pts−94.4 pts
Open the live comparison on ETFIQ
FMED and GDOC on the same fields, as of Sep 18, 2026. Source: ETFIQ.
FMED
Fidelity Disruptive Medicine ETF
Holds 68 stocks in broad innovation and megatrends, 25% of its weight in S&P 500 companies
GDOC
Goldman Sachs Future Health Care Equity ETF
Holds 41 stocks in broad innovation and megatrends, 57% of its weight in S&P 500 companies
IssuerFidelityGoldman Sachs
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50025.4%56.7%
Active share vs the S&P 50097.1%95.3%
In the Nasdaq-1008.7%9.4%
Holdings6841
Top ten, share of the fund31.5%58.2%
Expense ratio0.50%0.75%
Fee for the differing part0.51%0.79%
Total return, 1 year+28.3%+13.9%
vs the S&P 500+11.7 pts−2.6 pts
vs the Nasdaq-100+6.5 pts−7.8 pts
Below its high−3.8%−4.5%
Net assets$52m$19m

FMED in plain words

By weight, 25% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 97%. The top ten holdings are 32% of the fund across 68 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +28.3% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 11.7 pts.

GDOC in plain words

By weight, 57% of GDOC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 58% of the fund across 41 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +13.9% with distributions reinvested against +16.6% for the S&P 500, so a holder was behind by 2.6 pts.

Questions people ask

Do FMED and GDOC hold the same stocks?
By their latest filings, 24% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or GDOC?
FMED has 25% of its weight in S&P 500 names and GDOC has 57%, so FMED differs more from the index.
Which is cheaper, FMED or GDOC?
FMED charges 0.50% a year and GDOC charges 0.75%, so FMED is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

FMED against GDOC, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, FMED against GDOC, data as of Sep 18, 2026. https://etfiq.com/compare/themes/fmed-vs-gdoc Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources