Data as of Nov 4, 2026.

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Thematic ETFs

FMED vs THMZ: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, FMED returned +27.4% to THMZ's +6.1%; 6% of their weight is in the same names.

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Net assets: $52m on Sep 30, 2026 for Fidelity Disruptive Medicine ETF, and $54m on Jun 30, 2026 for Lazard Equity Megatrends ETF.

At a glance
21.8%
FMED in the S&P 500
53.9%
THMZ in the S&P 500
+27.4%
FMED total return, 1 year
+6.1%
THMZ total return, 1 year
FMED · 1 year to Nov 4, 2026 78% of its weight is outside the S&P 500
78% of its weight is outside the S&P 50022% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.22%78%in the S&P 500of its weight outside the S&P 500active share 98% · top ten 33% of the fund · 72 holdings as filed for Aug 31, 2026 · Nasdaq-100: 5% in78% of its weight is outside the S&P 50022% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.22%78%inoutside the S&P 500active share 98% · Nasdaq-100: 5% in

22% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.

THMZ · 1 year to Nov 4, 2026 46% of its weight is outside the S&P 500
46% of its weight is outside the S&P 50054% of THMZ's weight is in S&P 500 companies and 46% is outside the index. Holdings as of Jun 30, 2026.54%46%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 74% · top ten 34% of the fund · 59 holdings as filed for Jun 30, 2026 · Nasdaq-100: 30% in46% of its weight is outside the S&P 50054% of THMZ's weight is in S&P 500 companies and 46% is outside the index. Holdings as of Jun 30, 2026.54%46%in the S&P 500outsideactive share 74% · Nasdaq-100: 30% in

54% of THMZ's weight is in S&P 500 companies and 46% is outside the index. Holdings as of Jun 30, 2026.

Pair scorecard

Both cost 0.50% a year; their one-year returns differ by 21.3 points.

Points (pts) are percentage points.

FMED vs THMZ: Holdings Overlap & Returns
MeasureFMEDTHMZ
Return
Total return, 1 year+27.4%+6.1%
Against its benchmark
What it tracksBroad innovation and megatrendsBroad innovation and megatrends
Its benchmark, total return, 1 year+15.0%
Against its benchmark, 1 yearbehind by 8.9 pts
Cost and size
Expense ratio0.50%0.50%
Net assets, FMED as of Sep 30, 2026 and THMZ as of Jun 30, 2026$52m$54m
Holdings
Holdings in common6%

Method

Risk and return

Apr 17, 2025 to Oct 30, 2026 · 80 weekly returns
FMED THMZ
Return
Total return edge FMED +44.4% +29.1%
Annualized edge FMED +27.0% +18.1%
Price return edge FMED +44.4% +28.2%
Risk
Volatility edge THMZ 21.5% 15.9%
Max drawdown edge THMZ −18.1% −15.6%
Risk-adjusted
Sharpe edge FMED 1.03 0.87
Sortino edge FMED 1.85 1.49
Calmar edge FMED 1.50 1.16
Reading

From Apr 2025 to Oct 2026, FMED returned more: +44.4% to +29.1%. THMZ swung less: 15.9% to 21.5%. THMZ fell less at its worst: −15.6% to −18.1%.

Full scorecard

9 measures, with how each is measured
Open ↓
Risk and return: FMED vs THMZ: Holdings Overlap & Returns
MeasureFMEDTHMZEdgeHow it is measured
Return
Total return+44.4%+29.1%FMEDPrice change plus distributions, reinvested.
Annualized+27.0%+18.1%FMEDTotal return as a yearly rate.
Price return+44.4%+28.2%FMEDPrice change alone, distributions left out.
Risk
Volatility21.5%15.9%THMZSpread of weekly returns, annualized. Lower is steadier.
Downside deviation12.0%9.3%THMZLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−18.1%−15.6%THMZDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe1.030.87FMEDReturn above Treasury bills per unit of volatility.
Sortino1.851.49FMEDReturn above Treasury bills per unit of downside deviation.
Calmar1.501.16FMEDAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 80 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

6%

By the books each fund has filed, FMED and THMZ hold 6% of their money in the same securities at the same weight. Holdings dated Jun 30, 2026 and Aug 31, 2026.

0 half 100%

half

6% in common

Positions both hold · largest shared weight first FMED THMZ
THERMO FISHER SCIENTIFIC INC 3.83% 1.90%
DANAHER CORP 3.73% 1.88%
ELI LILLY and CO 0.89% 1.75%
ARGENX SE 3.20% 0.71%
BOSTON SCIENTIFIC CORP 1.14% 0.45%
Only in one fund ↓
Only in FMED
10X GENOMICS INC 5.19%
NATERA INC 3.30%
LIFESTANCE HEALTH GROUP INC 3.00%
REVOLUTION MEDICINES INC 2.87%
ILLUMINA INC 2.82%
MODERNA INC 2.72%
HEARTFLOW INC 2.59%
SARTORIUS STEDIM BIOTECH 2.56%
Only in THMZ
Taiwan Semiconductor Manufacturing Co Ltd 6.07%
Applied Materials Inc 5.54%
Alphabet Inc 3.54%
Amazon.com Inc 3.50%
Microsoft Corp 2.77%
NVIDIA Corp 2.76%
Mitsubishi Electric Corp 2.72%
Keysight Technologies Inc 2.59%
Check overlap with more funds →

Window by window

Window by window: FMED vs THMZ: Holdings Overlap & Returns
Total returnvs its benchmark
WindowFMEDTHMZFMEDTHMZ
3 months+14.9%−2.0%not measured−0.7 pts vs ACWI
6 months+31.2%+2.8%not measured+0.2 pts vs ACWI
1 year+27.4%+6.1%not measured−8.9 pts vs ACWI
3 years+57.8%–not measured–
Since launchNot the same days: FMED Jun 2023 · THMZ Apr 2025+31.7%+38.4%not measured−16.1 pts vs ACWI

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Side by side

FMED Fidelity Disruptive Medicine ETF · Holds 72 stocks in broad innovation and megatrends, 22% of its weight in S&P 500 companies THMZ Lazard Equity Megatrends ETF · Holds 59 stocks in broad innovation and megatrends, 54% of its weight in S&P 500 companies
Theme Broad innovation and megatrends Broad innovation and megatrends
In the S&P 500 21.8% 53.9%
Active share vs the S&P 500 97.5% 73.5%
In the Nasdaq-100 5.1% 29.5%
Holdings 72 59
Top ten, share of the fund 33.2% 34.3%
Expense ratio 0.50% 0.50%
Fee for the differing part 0.51% 0.68%
Total return, 1 year +27.4% +6.1%
vs its benchmark not measured −8.9 pts vs ACWI
Below its high −0.9% −2.6%
Net assets, FMED as of Sep 30, 2026 and THMZ as of Jun 30, 2026 $52m $54m

As of Nov 4, 2026. Source: ETFIQ.

6% of the two portfolios are the same securities at the same weight.

Client brief:

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About each fund
FMED

By weight, 22% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 33% of the fund across 72 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned +27.4% with distributions reinvested.

THMZ

By weight, 54% of THMZ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 74%. The top ten holdings are 34% of the fund across 59 positions, as filed for Jun 30, 2026. Over the year to Nov 4, 2026 the fund returned +6.1% with distributions reinvested against +15.0% for its benchmark, the MSCI ACWI Index, so a holder was behind by 8.9 pts.

Questions people ask

Do FMED and THMZ hold the same stocks?
By their latest filings, 6% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or THMZ?
FMED has 22% of its weight in S&P 500 names and THMZ has 54%, so FMED differs more from the index.
Which is cheaper, FMED or THMZ?
FMED and THMZ both charge 0.50% a year, so neither is cheaper. Fees come from each fund's prospectus.
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ETFIQ, FMED against THMZ, data as of Nov 4, 2026. https://etfiq.com/compare/themes/fmed-vs-thmz

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