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Data as of .

DTRE vs LFSC: which is really different?

DTRE and LFSC hold 0% of their weight in the same names, and LFSC returned more over the year.

First Trust Alerian Disruptive Technology Real Estate ETF and F/m Emerald Life Sciences Innovation ETF.

40.1%DTRE in the S&P 500
0.0%LFSC in the S&P 500
+8.0%DTRE total return, 1 year
+53.0%LFSC total return, 1 year

ETFIQ Off-Index Score: LFSC scores higher

How much of it is not the index it is sold as an alternative to?

DTRE 67.4LFSC 91.80.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

DTRE60% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
40%60%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 59% of the fund · 37 holdings filed Sep 18, 2026 · Nasdaq-100: 0% in40%60%in the S&P 500outside the S&P 500active share 99% · top ten 59% of the fund
LFSC100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund · 39 holdings filed May 31, 2026 · Nasdaq-100: 1% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, DTRE and LFSC hold 0% of their money in the same securities at the same weight.

Only in each
Only in DTREOnly in LFSC
American Tower Corporation 7.12%Travere Therapeutics Inc 7.66%
Digital Realty Trust, Inc. 6.86%Cogent Biosciences Inc 7.52%
Equinix, Inc. 6.66%LivaNova PLC 7.11%
SBA Communications Corporation 6.61%Spyre Therapeutics Inc 6.41%
Prologis, Inc. 6.44%Guardant Health Inc 5.51%
Crown Castle Inc. 6.43%Mirum Pharmaceuticals Inc 4.92%
Rexford Industrial Realty, Inc. 5.26%Corcept Therapeutics Inc 4.79%
Segro Plc 4.87%United Therapeutics Corp 4.15%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 18, 2026.

Performance, window by window

DTRE and LFSC over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
DTRELFSCDTRELFSCDTRELFSC
3 months+0.5%+8.7%−1.7 pts+6.5 pts+3.0 pts+11.2 pts
6 months+7.3%+36.0%−10.7 pts+17.9 pts−16.9 pts+11.7 pts
1 year+8.0%+53.0%−8.6 pts+36.5 pts−13.8 pts+31.3 pts
3 years+14.2%not published−64.2 ptsnot published−83.9 ptsnot published
Since launch+122.6%+81.3%−680.9 pts+44.3 pts−1567.6 pts+30.9 pts
Open the live comparison on ETFIQ
DTRE and LFSC on the same fields, as of Sep 18, 2026. Source: ETFIQ.
DTRE
First Trust Alerian Disruptive Technology Real Estate ETF
Holds 37 stocks in broad innovation and megatrends, 40% of its weight in S&P 500 companies
LFSC
F/m Emerald Life Sciences Innovation ETF
Holds 39 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
IssuerFirst TrustF/m
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 50040.1%0.0%
Active share vs the S&P 50099.4%100.0%
In the Nasdaq-1000.0%0.6%
Holdings3739
Top ten, share of the fund59.2%54.7%
Expense ratio0.60%0.54%
Fee for the differing part0.60%0.54%
Total return, 1 year+8.0%+53.0%
vs the S&P 500−8.6 pts+36.5 pts
vs the Nasdaq-100−13.8 pts+31.3 pts
Below its high−12.9%−6.8%
Net assets$14m$105m

DTRE in plain words

By weight, 40% of DTRE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 59% of the fund across 37 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +8.0% with distributions reinvested against +16.6% for the S&P 500, so a holder was behind by 8.6 pts. It sits 12.9% below its all-time high of Dec 31, 2021.

LFSC in plain words

By weight, 0% of LFSC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 55% of the fund across 39 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +53.0% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 36.5 pts. It sits 6.8% below its all-time high of Aug 19, 2026.

Questions people ask

Do DTRE and LFSC hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, DTRE or LFSC?
DTRE has 40% of its weight in S&P 500 names and LFSC has 0%, so LFSC differs more from the index.
Which is cheaper, DTRE or LFSC?
DTRE charges 0.60% a year and LFSC charges 0.54%, so LFSC is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

DTRE against LFSC, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, DTRE against LFSC, data as of Sep 18, 2026. https://etfiq.com/compare/themes/dtre-vs-lfsc Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources