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Data as of .

GXDW vs LFSC: which is really different?

GXDW and LFSC hold 0% of their weight in the same names, and LFSC returned more over the year.

Global X Dorsey Wright Thematic ETF and F/m Emerald Life Sciences Innovation ETF.

0.0%GXDW in the S&P 500
0.0%LFSC in the S&P 500
−10.2%GXDW total return, 1 year
+53.0%LFSC total return, 1 year

ETFIQ Off-Index Score: GXDW scores higher

How much of it is not the index it is sold as an alternative to?

GXDW 91.8LFSC 91.80.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

GXDW100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 100% of the fund · 7 holdings filed Sep 18, 2026 · Nasdaq-100: 0% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 100% of the fund
LFSC100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund · 39 holdings filed May 31, 2026 · Nasdaq-100: 1% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 55% of the fund

0% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, GXDW and LFSC hold 0% of their money in the same securities at the same weight.

Only in each
Only in GXDWOnly in LFSC
GLOBAL X HYDROGEN ETF 20.93%Travere Therapeutics Inc 7.66%
GLOBAL X GENOMICS & BIOTECHN 20.55%Cogent Biosciences Inc 7.52%
GLOBAL X CYBERSECURITY ETF 20.21%LivaNova PLC 7.11%
GLOBAL X ART INTEL & TECH 19.89%Spyre Therapeutics Inc 6.41%
GLOBAL X LITHIUM & BATTERY T 18.41%Guardant Health Inc 5.51%
OTHER PAYABLE & RECEIVABLES 0.01%Mirum Pharmaceuticals Inc 4.92%
CASH -0.01%Corcept Therapeutics Inc 4.79%
United Therapeutics Corp 4.15%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated May 31, 2026 and Sep 18, 2026.

Performance, window by window

GXDW and LFSC over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
GXDWLFSCGXDWLFSCGXDWLFSC
3 months−13.3%+8.7%−15.5 pts+6.5 pts−10.8 pts+11.2 pts
6 months+10.8%+36.0%−7.2 pts+17.9 pts−13.4 pts+11.7 pts
1 year−10.2%+53.0%−26.8 pts+36.5 pts−32.0 pts+31.3 pts
3 years+3.7%not published−74.7 ptsnot published−94.5 ptsnot published
Since launch+2.3%+81.3%−171.8 pts+44.3 pts−273.6 pts+30.9 pts
Open the live comparison on ETFIQ
GXDW and LFSC on the same fields, as of Sep 18, 2026. Source: ETFIQ.
GXDW
Global X Dorsey Wright Thematic ETF
Holds 7 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
LFSC
F/m Emerald Life Sciences Innovation ETF
Holds 39 stocks in broad innovation and megatrends, 0% of its weight in S&P 500 companies
IssuerGlobal XF/m
ThemeBroad innovation and megatrendsBroad innovation and megatrends
In the S&P 5000.0%0.0%
Active share vs the S&P 500100.0%100.0%
In the Nasdaq-1000.0%0.6%
Holdings739
Top ten, share of the fund100.0%54.7%
Expense ratio0.50%0.54%
Fee for the differing part0.50%0.54%
Total return, 1 year−10.2%+53.0%
vs the S&P 500−26.8 pts+36.5 pts
vs the Nasdaq-100−32.0 pts+31.3 pts
Below its high−59.4%−6.8%
Net assets$6m$105m

GXDW in plain words

By weight, 0% of GXDW's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 100% of the fund across 7 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned −10.2% with distributions reinvested against +16.6% for the S&P 500, so a holder was behind by 26.8 pts. It sits 59.4% below its all-time high of Feb 10, 2021.

LFSC in plain words

By weight, 0% of LFSC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 55% of the fund across 39 positions, as filed for May 31, 2026. Over the year to Sep 18, 2026 the fund returned +53.0% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 36.5 pts. It sits 6.8% below its all-time high of Aug 19, 2026.

Questions people ask

Do GXDW and LFSC hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, GXDW or LFSC?
GXDW has 0% of its weight in S&P 500 names and LFSC has 0%, so GXDW differs more from the index.
Which is cheaper, GXDW or LFSC?
GXDW charges 0.50% a year and LFSC charges 0.54%, so GXDW is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

GXDW against LFSC, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, GXDW against LFSC, data as of Sep 18, 2026. https://etfiq.com/compare/themes/gxdw-vs-lfsc Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources