Data as of Oct 28, 2026.

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Across categories

IBB vs VGIT: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VGIT's −1.5%, and VGIT charges 0.03% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $39.7bn on Sep 30, 2026 for Vanguard Intermediate-Term Treasury ETF.

At a glance
+37.5%
IBB total return, 1 year
−1.5%
VGIT total return, 1 year
0.44%
IBB expense ratio
0.03%
VGIT expense ratio

Pair scorecard

VGIT costs 0.41 points a year less; their one-year returns differ by 39.0 points; VGIT is 3.5 times larger.

IBB vs VGIT: Differences, Returns & Fees
MeasureIBBVGIT
Return
Total return, 1 year+37.5%−1.5%
Drawdown
Below its high3.5%, high on Aug 4, 2020
Benchmark
What it tracksBiotechBloomberg U.S. Treasury 3-10 Year Index
Cost and size
Expense ratio0.44%0.03%
Net assets, as of Sep 30, 2026$11.2bn$39.7bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
In the S&P 500, by weight40%
Top ten holdings, share of the fund50%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and VGIT hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB VGIT
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in VGIT
United States Treasury Note/Bond 1.91%
United States Treasury Note/Bond 1.89%
United States Treasury Note/Bond 1.87%
United States Treasury Note/Bond 1.85%
United States Treasury Note/Bond 1.83%
United States Treasury Note/Bond 1.82%
United States Treasury Note/Bond 1.82%
United States Treasury Note/Bond 1.81%
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Side by side

IBB iShares Biotechnology ETF VGIT Vanguard Intermediate-Term Treasury ETF
Where it sits Thematic ETF Bond ETF
What it is Biotech Tracks an index of Intermediate-Term Treasury
Total return, 1 year +37.5% −1.5%
Its benchmark over the same days not measured −1.5% (SCHR)
Gap to its benchmark not measured 0.0 pts vs SCHR
Expense ratio 0.44% 0.03%
Holdings 245 103
Net assets, IBB as of Oct 27, 2026 and VGIT as of Sep 30, 2026 $11.0bn $39.7bn

IBB and VGIT on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VGIT

VGIT tracks an index of Intermediate-Term Treasury. Over the year to Oct 28, 2026 it returned −1.5% with distributions reinvested, against −1.5% for its benchmark, the Bloomberg U.S. Treasury 3-10 Year Index. The prospectus expense ratio is 0.03% a year. It sat 3.5% below its high of Aug 4, 2020 on Oct 28, 2026.

Questions people ask

Are IBB and VGIT in the same category?
IBB is a thematic ETF and VGIT is a bond ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VGIT?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VGIT −1.5%.
Which is cheaper, IBB or VGIT?
VGIT is cheaper, by 0.41 percentage points a year. That is about $41 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, IBB against VGIT, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vgit

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