Data as of Oct 28, 2026.

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IBB vs IEF: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to IEF's −3.2%, and IEF charges 0.15% to IBB's 0.44%.

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Net assets on Oct 27, 2026: $11.0bn for iShares Biotechnology ETF and $43.5bn for iShares 7-10 Year Treasury Bond ETF.

At a glance
+37.5%
IBB total return, 1 year
−3.2%
IEF total return, 1 year
0.44%
IBB expense ratio
0.15%
IEF expense ratio

Pair scorecard

IEF costs 0.29 points a year less; their one-year returns differ by 40.7 points; IEF is 4.0 times larger.

IBB vs IEF: Differences, Returns & Fees
MeasureIBBIEF
Return
Total return, 1 year+37.5%−3.2%
Drawdown
Below its high13.1%, high on Aug 4, 2020
Benchmark
What it tracksBiotechICE U.S. Treasury 7-10 Year Bond Index
Cost and size
Expense ratio0.44%0.15%
Net assets, as of Oct 27, 2026$11.0bn$43.5bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
In the S&P 500, by weight40%
Top ten holdings, share of the fund50%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and IEF hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB IEF
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in IEF
TREASURY NOTE 8.82%
TREASURY NOTE 8.80%
TREASURY NOTE 8.74%
TREASURY NOTE 8.68%
TREASURY NOTE (OLD) 8.68%
TREASURY NOTE (2OLD) 8.65%
TREASURY NOTE 8.48%
TREASURY NOTE 8.40%
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Side by side

IBB iShares Biotechnology ETF IEF iShares 7-10 Year Treasury Bond ETF
Where it sits Thematic ETF Bond ETF
What it is Biotech Tracks an index of 7-10 Year Treasury Bond
Total return, 1 year +37.5% −3.2%
Expense ratio 0.44% 0.15%
Holdings 245 17
Net assets, as of Oct 27, 2026 $11.0bn $43.5bn

IBB and IEF on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

IEF

IEF tracks an index of 7-10 Year Treasury Bond. Over the year to Oct 28, 2026 it returned −3.2% with distributions reinvested. The prospectus expense ratio is 0.15% a year. It sat 13.1% below its high of Aug 4, 2020 on Oct 28, 2026.

Questions people ask

Are IBB and IEF in the same category?
IBB is a thematic ETF and IEF is a bond ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or IEF?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and IEF −3.2%.
Which is cheaper, IBB or IEF?
IEF is cheaper, by 0.29 percentage points a year. That is about $29 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, IBB against IEF, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-ief

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