Data as of Oct 28, 2026.

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IBB vs VGSH: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VGSH's +1.7%, and VGSH charges 0.03% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $35.1bn on Sep 30, 2026 for Vanguard Short-Term Treasury ETF.

At a glance
+37.5%
IBB total return, 1 year
+1.7%
VGSH total return, 1 year
0.44%
IBB expense ratio
0.03%
VGSH expense ratio

Pair scorecard

VGSH costs 0.41 points a year less; their one-year returns differ by 35.8 points; VGSH is 3.1 times larger.

IBB vs VGSH: Differences, Returns & Fees
MeasureIBBVGSH
Return
Total return, 1 year+37.5%+1.7%
Benchmark
What it tracksBiotechBloomberg U.S. Treasury 1-3 Year Index
Cost and size
Expense ratio0.44%0.03%
Net assets, as of Sep 30, 2026$11.2bn$35.1bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
In the S&P 500, by weight40%
Top ten holdings, share of the fund50%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

Risk and return

Dec 4, 2009 to Oct 23, 2026 · 881 weekly returns
IBB VGSH
Return
Total return edge IBB +714.7% +26.7%
Annualized edge IBB +13.2% +1.4%
Price return edge IBB +682.5% −3.7%
Risk
Volatility edge VGSH 22.6% 1.3%
Max drawdown edge VGSH −37.5% −5.5%
Risk-adjusted
Sharpe edge IBB 0.59 −0.09
Sortino edge IBB 0.87 −0.14
Calmar edge IBB 0.35 0.26
Reading

IBB returned more: +714.7% to +26.7%. VGSH swung less: 1.3% to 22.6%. VGSH fell less at its worst: −5.5% to −37.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: IBB vs VGSH: Differences, Returns & Fees
MeasureIBBVGSHEdgeHow it is measured
Return
Total return+714.7%+26.7%IBBPrice change plus distributions, reinvested.
Annualized+13.2%+1.4%IBBTotal return as a yearly rate.
Price return+682.5%−3.7%IBBPrice change alone, distributions left out.
Risk
Volatility22.6%1.3%VGSHSpread of weekly returns, annualized. Lower is steadier.
Downside deviation15.5%0.9%VGSHLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.5%−5.5%VGSHDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.59−0.09IBBReturn above Treasury bills per unit of volatility.
Sortino0.87−0.14IBBReturn above Treasury bills per unit of downside deviation.
Calmar0.350.26IBBAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 881 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

0%

By the books each fund has filed, IBB and VGSH hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB VGSH
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in VGSH
United States Treasury Note/Bond 2.07%
United States Treasury Note/Bond 1.43%
United States Treasury Note/Bond 1.39%
United States Treasury Note/Bond 1.37%
United States Treasury Note/Bond 1.35%
United States Treasury Note/Bond 1.34%
United States Treasury Note/Bond 1.33%
United States Treasury Note/Bond 1.33%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VGSH Vanguard Short-Term Treasury ETF
Where it sits Thematic ETF Bond ETF
What it is Biotech Tracks an index of Short-Term Treasury
Total return, 1 year +37.5% +1.7%
Its benchmark over the same days not measured +1.8% (SCHO)
Gap to its benchmark not measured −0.1 pts vs SCHO
Expense ratio 0.44% 0.03%
Holdings 245 93
Net assets, IBB as of Oct 27, 2026 and VGSH as of Sep 30, 2026 $11.0bn $35.1bn

IBB and VGSH on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-C6AB531F5A

IBB and VGSH do different jobs. What does each one do in a portfolio?

  1. What each follows. IBB follows Biotech and VGSH follows Bloomberg U.S. Treasury 1-3 Year Index.
  2. Holdings in common. 0% of the weight is in the same securities (holdings dated Oct 27, 2026 and Sep 30, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 IBB returned +37.5% and VGSH +1.7% with distributions reinvested, a gap of 35.8 points.

Data as of Oct 28, 2026.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VGSH

VGSH tracks an index of Short-Term Treasury. Over the year to Oct 28, 2026 it returned +1.7% with distributions reinvested, against +1.8% for its benchmark, the Bloomberg U.S. Treasury 1-3 Year Index. The prospectus expense ratio is 0.03% a year.

Questions people ask

Are IBB and VGSH in the same category?
IBB is a thematic ETF and VGSH is a bond ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VGSH?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VGSH +1.7%.
Which is cheaper, IBB or VGSH?
VGSH is cheaper, by 0.41 percentage points a year. That is about $41 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, IBB against VGSH, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vgsh

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.