Health care sector ETFs: all 23

23 health care sector ETFs, placed by ETFIQ from each fund’s own filings. Concentrated in drug makers, biotechnology, medical devices and health services. Each is listed with its one-year return, its gap to the S&P 500, its fee and its net assets.

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The 10 largest health care sector ETFs

ETFIQ covers 23 health care sector ETFs. The largest are XLV ($42.7bn), VHT ($19.1bn) and IXJ ($4.3bn); fees run 0.08% to 0.85%, as of .

  1. 1XLV$42.7bn0.08%State Street Health Care Select Sector SPDR ETF
  2. 2VHT$19.1bn0.09%Vanguard Health Care ETF
  3. 3IXJ$4.3bn0.38%iShares Global Healthcare ETF
  4. 4IYH$3.9bn0.37%iShares U.S. Healthcare ETF
  5. 5FHLC$3.5bn0.08%Fidelity MSCI Health Care Index ETF
  6. 6IHE$1.6bn0.37%iShares U.S. Pharmaceuticals ETF
  7. 7IHF$1.4bn0.37%iShares U.S. Healthcare Providers ETF
  8. 8FXH$1.1bn0.61%First Trust Health Care AlphaDEX Fund
  9. 9FTXH$1.0bn0.60%First Trust Nasdaq Pharmaceuticals ETF
  10. 10RSPH$875m0.40%Invesco S&P 500 Equal Weight Health Care ETF

Every health care sector ETF, largest first

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Net assets
TickerFundTracksTotal return 1Yvs S&P 500 1YFeeNet assets
XLVState Street Health Care Select Sector SPDR ETFHealth care+18.0%+1.7 pts0.08%$42.7bn
VHTVanguard Health Care ETFHealth Care+18.9%+2.7 pts0.09%$19.1bn
IXJiShares Global Healthcare ETFnot read by ETFIQ+11.8%−4.4 pts0.38%$4.3bn
IYHiShares U.S. Healthcare ETFnot read by ETFIQ+17.9%+1.7 pts0.37%$3.9bn
FHLCFidelity MSCI Health Care Index ETFnot read by ETFIQ+19.1%+2.8 pts0.08%$3.5bn
IHEiShares U.S. Pharmaceuticals ETFnot read by ETFIQ+34.4%+18.1 pts0.37%$1.6bn
IHFiShares U.S. Healthcare Providers ETFnot read by ETFIQ+11.6%−4.7 pts0.37%$1.4bn
FXHFirst Trust Health Care AlphaDEX Fundnot read by ETFIQ+15.8%−0.4 pts0.61%$1.1bn
FTXHFirst Trust Nasdaq Pharmaceuticals ETFnot read by ETFIQ+39.1%+22.9 pts0.60%$1.0bn
RSPHInvesco S&P 500 Equal Weight Health Care ETFnot read by ETFIQ+22.3%+6.1 pts0.40%$875m
PJPInvesco Pharmaceuticals ETFnot read by ETFIQ+29.4%+13.1 pts0.58%$545m
XPHState Street SPDR S&P Pharmaceuticals ETFnot read by ETFIQ+32.5%+16.2 pts0.35%$510m
PINKSimplify Health Care ETFNo index (active)+17.6%+1.3 pts0.51%$342m
PTHInvesco Dorsey Wright Healthcare Momentum ETFnot read by ETFIQ+38.8%+22.5 pts0.60%$292m
XHSState Street SPDR S&P Health Care Services ETFnot read by ETFIQ+31.7%+15.4 pts0.35%$219m
XHEState Street SPDR S&P Health Care Equipment ETFnot read by ETFIQ+12.1%−4.2 pts0.35%$181m
PSCHInvesco S&P SmallCap Health Care ETFnot read by ETFIQ+22.3%+6.1 pts0.29%$175m
SBIOALPS Medical Breakthroughs ETFnot read by ETFIQ+43.9%+27.7 pts0.50%$162m
HRTSTema Heart & Health ETFNo index (active)+13.8%−2.4 pts0.75%$53m
MEDIHarbor Health Care ETFNo index (active)+11.4%−4.8 pts0.80%$41m
TMEDT. Rowe Price Health Care ETFNo index (active)+21.4%+5.2 pts0.44%$23m
MEDXHorizon Kinetics Medical ETFNo index (active)+11.3%−5.0 pts0.85%$19m
JDOCJPMorgan Healthcare Leaders ETFNo index (active)+11.6%−4.6 pts0.65%$9m
23 funds, sorted by the order on the page.

23 Health care sector ETFs, largest first, as of Oct 2, 2026. Source: ETFIQ.

Cite this page

ETFIQ, Health care sector ETFs: all 23, data as of Oct 2, 2026. https://etfiq.com/stocks/health/

Cite this page. ETFIQ, Health care sector ETFs: all 23, data as of Oct 2, 2026. https://etfiq.com/stocks/health/ Free to use with attribution; the underlying files are at Open data.

Open data

Free to use with attribution; the underlying files are at Open data.