Do FMED and ILDR hold the same stocks?

By their latest filings, 5% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, FMED or ILDR?

FMED has 22% of its weight in S&P 500 names and ILDR has 66%, so FMED differs more from the index.

Which is cheaper, FMED or ILDR?

FMED charges 0.50% a year and ILDR charges 0.75%, so FMED is cheaper. Fees come from each fund's prospectus.

Data as of Nov 4, 2026.

Thematic ETFs

FMED vs ILDR: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, FMED returned +27.4% to ILDR's +6.6%; 5% of their weight is in the same names.

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Net assets: $52m on Sep 30, 2026 for Fidelity Disruptive Medicine ETF, and $334m on Nov 3, 2026 for First Trust Innovation Leaders ETF.

FMED on its own →ILDR on its own →

At a glance

21.8%

FMED in the S&P 500

65.5%

ILDR in the S&P 500

+27.4%

FMED total return, 1 year

+6.6%

ILDR total return, 1 year

FMED · 1 year to Nov 4, 2026 78% of its weight is outside the S&P 500

22% of FMED's weight is in S&P 500 companies and 78% is outside the index. Holdings as of Aug 31, 2026.

ILDR · 1 year to Nov 4, 2026 35% of its weight is outside the S&P 500

66% of ILDR's weight is in S&P 500 companies and 35% is outside the index. Holdings as of Nov 3, 2026.

Pair scorecard

FMED costs 0.25 points a year less; their one-year returns differ by 20.8 points.

Points (pts) are percentage points.

FMED vs ILDR: Holdings Overlap & Returns
Measure	FMED	ILDR
Return
Measure	FMED	ILDR
Total return, 1 year	+27.4%	+6.6%
Drawdown
Measure	FMED	ILDR
Below its all-time high		12.5%, high on Oct 6, 2026
Against its benchmark
Measure	FMED	ILDR
What it tracks	Broad innovation and megatrends	Broad innovation and megatrends
Its benchmark, total return, 1 year		+14.8%
Against its benchmark, 1 year		behind by 8.2 pts
Cost and size
Measure	FMED	ILDR
Expense ratio	0.50%	0.75%
Net assets, FMED as of Sep 30, 2026 and ILDR as of Nov 3, 2026	$52m	$334m
Holdings
Measure	FMED	ILDR
Holdings in common	5%

Method

What they share

By the books each fund has filed, FMED and ILDR hold 5% of their money in the same securities at the same weight. Holdings dated Aug 31, 2026 and Nov 3, 2026.

50%

0 half 100%

half

5% in common

Positions both hold · largest shared weight first FMED ILDR

ASCENDIS PHARMA A/S 1.97% 1.07%

ELI LILLY and CO 0.89% 4.02%

ARGENX SE 3.20% 0.88%

KYMERA THERAPEUTICS INC 1.96% 0.59%

VIRIDIAN THERAPEUTICS INC 1.40% 0.58%

ALNYLAM PHARMACEUTICALS INC 2.33% 0.42%

MIRUM PHARMACEUTICALS INC 0.42% 0.93%

Only in one fund ↓

Only in FMED

10X GENOMICS INC 5.19%

THERMO FISHER SCIENTIFIC INC 3.83%

DANAHER CORP 3.73%

NATERA INC 3.30%

LIFESTANCE HEALTH GROUP INC 3.00%

REVOLUTION MEDICINES INC 2.87%

ILLUMINA INC 2.82%

MODERNA INC 2.72%

Only in ILDR

NVIDIA Corporation 9.90%

Amazon.com, Inc. 6.23%

Advanced Micro Devices, Inc. 5.45%

Alphabet Inc. (Class A) 4.20%

Broadcom Inc. 3.61%

Microsoft Corporation 3.11%

Micron Technology, Inc. 2.56%

Oracle Corporation 2.48%

Check overlap with more funds →

Window by window

Window by window: FMED vs ILDR: Holdings Overlap & Returns
	Total return		vs its benchmark
Window	FMED	ILDR	FMED	ILDR
3 months	+14.9%	−7.4%	not measured	−7.1 pts vs IWV
6 months	+31.2%	−1.8%	not measured	−6.7 pts vs IWV
1 year	+27.4%	+6.6%	not measured	−8.2 pts vs IWV
3 years	+57.8%	+107.0%	not measured	+26.0 pts vs IWV
Since launchNot the same days: FMED Jun 2023 · ILDR May 2021	+31.7%	+75.9%	not measured	−10.3 pts vs IWV

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Side by side

FMED Fidelity Disruptive Medicine ETF · Holds 72 stocks in broad innovation and megatrends, 22% of its weight in S&P 500 companies ILDR First Trust Innovation Leaders ETF · Holds 81 stocks in broad innovation and megatrends, 66% of its weight in S&P 500 companies

Issuer Fidelity First Trust

Theme Broad innovation and megatrends Broad innovation and megatrends

In the S&P 500 21.8% 65.5%

Active share vs the S&P 500 97.5% 66.9%

In the Nasdaq-100 5.1% 48.8%

Holdings 72 81

Top ten, share of the fund 33.2% 44.0%

Expense ratio 0.50% 0.75%

Fee for the differing part 0.51% 1.12%

Total return, 1 year +27.4% +6.6%

vs its benchmark not measured −8.2 pts vs IWV

Below its high −0.9% −12.5%

Net assets, FMED as of Sep 30, 2026 and ILDR as of Nov 3, 2026 $52m $334m

As of Nov 4, 2026. Source: ETFIQ.

5% of the two portfolios are the same securities at the same weight.

Alert

About each fund

FMED

By weight, 22% of FMED's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 33% of the fund across 72 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned +27.4% with distributions reinvested.

ILDR

Over the year to Nov 4, 2026 the fund returned +6.6% with distributions reinvested against +14.8% for its benchmark, the Russell 3000 Index, so a holder was behind by 8.2 pts.

By weight, 66% of ILDR's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 67%. The top ten holdings are 44% of the fund across 81 positions, as published by its issuer for Nov 3, 2026. It sits 12.5% below its all-time high of Oct 6, 2026.

Questions people ask

Do FMED and ILDR hold the same stocks?: By their latest filings, 5% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FMED or ILDR?: FMED has 22% of its weight in S&P 500 names and ILDR has 66%, so FMED differs more from the index.
Which is cheaper, FMED or ILDR?: FMED charges 0.50% a year and ILDR charges 0.75%, so FMED is cheaper. Fees come from each fund's prospectus.

Other comparisons

FMED vs HTEC FMED vs ARKK FMED vs FRWD FMED vs TMAT ILDR vs THMZ ILDR vs TEKY ILDR vs LENS ILDR vs GDOC

Where to next

All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →FMED on its own →ILDR on its own →FMED dividend history →FMED holdings →ILDR holdings →Method →Standards and sources →

Sources and dates

FMED filings on SEC EDGAR ↗

FMED prospectus with the expense ratio (SEC) ↗

Fidelity website ↗

ILDR filings on SEC EDGAR ↗

ILDR prospectus with the expense ratio (SEC) ↗

First Trust page for ILDR ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

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ETFIQ, FMED against ILDR, data as of Nov 4, 2026. https://etfiq.com/compare/themes/fmed-vs-ildr

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.