Data as of Oct 28, 2026.

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Across categories

IBB vs VPU: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VPU's −3.3%, and VPU charges 0.09% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $7.7bn on Sep 30, 2026 for Vanguard Utilities ETF.

At a glance
+37.5%
IBB total return, 1 year
−3.3%
VPU total return, 1 year
0.44%
IBB expense ratio
0.09%
VPU expense ratio

Pair scorecard

VPU costs 0.35 points a year less; their one-year returns differ by 40.8 points; IBB is 1.5 times larger.

IBB vs VPU: Differences, Returns & Fees
MeasureIBBVPU
Return
Total return, 1 year+37.5%−3.3%
Drawdown
Below its high8.9%, high on Feb 27, 2026
Benchmark
What it tracksBiotechMSCI US Investable Market Index (IMI)/Utilities 25/50
Cost and size
Expense ratio0.44%0.09%
Net assets, as of Sep 30, 2026$11.2bn$7.7bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%52.3%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and VPU hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB VPU
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in VPU
NextEra Energy Inc 11.39%
Southern Co 6.74%
Duke Energy Corp 6.41%
Constellation Energy Corp 5.72%
American Electric Power Co Inc 4.66%
Dominion Energy Inc 3.84%
Sempra 3.68%
Vistra Corp 3.37%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VPU Vanguard Utilities ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Utilities
Total return, 1 year +37.5% −3.3%
Its benchmark over the same days not measured −3.3% (FUTY)
Gap to its benchmark not measured 0.0 pts vs FUTY
Expense ratio 0.44% 0.09%
Already in the S&P 500 40.2% 89.7%
Holdings 245 70
Net assets, IBB as of Oct 27, 2026 and VPU as of Sep 30, 2026 $11.0bn $7.7bn

IBB and VPU on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VPU

VPU tracks an index of Utilities. Over the year to Oct 28, 2026 it returned −3.3% with distributions reinvested, against −3.3% for its benchmark, the MSCI US Investable Market Index (IMI)/Utilities 25/50. The prospectus expense ratio is 0.09% a year. By its holdings published by its issuer as of Sep 30, 2026, 90% of the fund by weight is stocks the S&P 500 also holds, across 70 positions, with the top ten at 52.3%. It sat 8.9% below its high of Feb 27, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and VPU in the same category?
IBB is a thematic ETF and VPU is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VPU?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VPU −3.3%.
Which is cheaper, IBB or VPU?
VPU is cheaper, by 0.35 percentage points a year. That is about $35 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VPU overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 90% of VPU by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against VPU, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vpu

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