Data as of Oct 28, 2026.

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IBB vs VHT: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VHT's +25.0%, and VHT charges 0.09% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $19.1bn on Sep 30, 2026 for Vanguard Health Care ETF.

At a glance
+37.5%
IBB total return, 1 year
+25.0%
VHT total return, 1 year
0.44%
IBB expense ratio
0.09%
VHT expense ratio

Pair scorecard

VHT costs 0.35 points a year less; their one-year returns differ by 12.5 points; VHT is 1.7 times larger.

IBB vs VHT: Differences, Returns & Fees
MeasureIBBVHT
Return
Total return, 1 year+37.5%+25.0%
Benchmark
What it tracksBiotechMSCI US Investable Market Index (IMI)/Health Care 25/50
Cost and size
Expense ratio0.44%0.09%
Net assets, as of Sep 30, 2026$11.2bn$19.1bn
Active share vs the S&P 50099%
Holdings
Holdings in common19%
Top ten holdings, share of the fund50%51.8%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

Risk and return

Feb 6, 2004 to Oct 23, 2026 · 1,185 weekly returns
IBB VHT
Return
Total return edge VHT (slight) +738.4% +797.6%
Annualized edge VHT (slight) +9.8% +10.1%
Price return edge IBB +702.6% +552.3%
Risk
Volatility edge VHT 22.5% 16.4%
Max drawdown edge Tie −37.5% −38.1%
Risk-adjusted
Sharpe edge VHT 0.45 0.56
Sortino edge VHT 0.64 0.79
Calmar edge Tie 0.26 0.27
Reading

VHT returned slightly more: +797.6% to +738.4%. VHT swung less: 16.4% to 22.5%. IBB and VHT fell about the same at their worst: −37.5% and −38.1%.

Full scorecard

9 measures, with how each is measured
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Risk and return: IBB vs VHT: Differences, Returns & Fees
MeasureIBBVHTEdgeHow it is measured
Return
Total return+738.4%+797.6%VHT (slight)Price change plus distributions, reinvested.
Annualized+9.8%+10.1%VHT (slight)Total return as a yearly rate.
Price return+702.6%+552.3%IBBPrice change alone, distributions left out.
Risk
Volatility22.5%16.4%VHTSpread of weekly returns, annualized. Lower is steadier.
Downside deviation15.7%11.6%VHTLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.5%−38.1%TieDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.450.56VHTReturn above Treasury bills per unit of volatility.
Sortino0.640.79VHTReturn above Treasury bills per unit of downside deviation.
Calmar0.260.27TieAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,185 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

19%

By the books each fund has filed, IBB and VHT hold 19% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

19% in common

Positions both hold · largest shared weight first IBB VHT
AMGEN INC 8.20% 3.18%
GILEAD SCIENCES 8.56% 2.59%
VERTEX PHARMACEUTICALS 7.53% 1.85%
REGENERON PHARMACEUTICALS 5.64% 1.09%
MODERNA 5.29% 0.91%
NATERA 3.85% 0.79%
ILLUMINA INC 2.93% 0.56%
REVOLUTION MEDICINES 2.50% 0.49%
BIOGEN 2.58% 0.47%
ALNYLAM PHARMACEUTICALS 2.11% 0.46%
INSMED 1.42% 0.34%
UNITED THERAPEUTICS 1.71% 0.29%
Only in one fund ↓
Only in IBB
ARGENX SE ADR 3.42%
BEONE MEDICINES AG 2.15%
GENMAB SPONSORED ADR 1.72%
ASCENDIS PHARMA 1.06%
BIONTECH SE ADR 0.58%
ABIVAX AMERICAN DEPOSITARY SHARES 0.44%
CRISPR THERAPEUTICS AG 0.32%
CARIS LIFE SCIENCES 0.30%
Only in VHT
Eli Lilly & Co 12.95%
Johnson & Johnson 8.79%
AbbVie Inc 6.46%
Merck & Co Inc 5.02%
UnitedHealth Group Inc 4.66%
Thermo Fisher Scientific Inc 3.51%
Abbott Laboratories 2.41%
Pfizer Inc 2.27%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VHT Vanguard Health Care ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Health Care
Total return, 1 year +37.5% +25.0%
Its benchmark over the same days not measured +25.4% (FHLC)
Gap to its benchmark not measured −0.4 pts vs FHLC
Expense ratio 0.44% 0.09%
Already in the S&P 500 40.2% 85.5%
Holdings 245 414
Net assets, IBB as of Oct 27, 2026 and VHT as of Sep 30, 2026 $11.0bn $19.1bn

IBB and VHT on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-CD085A63E4

IBB and VHT do different jobs. What does each one do in a portfolio?

  1. What each follows. IBB follows Biotech and VHT follows MSCI US Investable Market Index (IMI)/Health Care 25/50.
  2. Holdings in common. 19% of the weight is in the same securities (holdings dated Oct 27, 2026 and Sep 30, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 IBB returned +37.5% and VHT +25.0% with distributions reinvested, a gap of 12.5 points.

Data as of Oct 28, 2026.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VHT

VHT tracks an index of Health Care. Over the year to Oct 28, 2026 it returned +25.0% with distributions reinvested, against +25.4% for its benchmark, the MSCI US Investable Market Index (IMI)/Health Care 25/50. The prospectus expense ratio is 0.09% a year. By its holdings published by its issuer as of Sep 30, 2026, 86% of the fund by weight is stocks the S&P 500 also holds, across 414 positions, with the top ten at 51.8%.

Questions people ask

Are IBB and VHT in the same category?
IBB is a thematic ETF and VHT is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VHT?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VHT +25.0%.
Which is cheaper, IBB or VHT?
VHT is cheaper, by 0.35 percentage points a year. That is about $35 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VHT overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 86% of VHT by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against VHT, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vht

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.