Data as of Oct 28, 2026.

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Across categories

IBB vs VPL: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VPL's +24.8%, and VPL charges 0.07% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $9.0bn on Sep 30, 2026 for Vanguard FTSE Pacific ETF.

At a glance
+37.5%
IBB total return, 1 year
+24.8%
VPL total return, 1 year
0.44%
IBB expense ratio
0.07%
VPL expense ratio

Pair scorecard

VPL costs 0.37 points a year less; their one-year returns differ by 12.7 points; IBB is 1.2 times larger.

IBB vs VPL: Differences, Returns & Fees
MeasureIBBVPL
Return
Total return, 1 year+37.5%+24.8%
Drawdown
Below its high7.2%, high on Jun 22, 2026
Benchmark
What it tracksBiotechFTSE Developed Asia Pacific All Cap Index
Cost and size
Expense ratio0.44%0.07%
Net assets, as of Sep 30, 2026$11.2bn$9.0bn
Active share vs the S&P 50099%
Holdings
Holdings in common0%
Top ten holdings, share of the fund50%24.8%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IBB and VPL hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IBB VPL
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
Only in VPL
Samsung Electronics Co Ltd 7.11%
SK hynix Inc 5.82%
Mitsubishi UFJ Financial Group Inc 1.98%
BHP Group Ltd 1.69%
SLBBH1142 1.57%
Toyota Motor Corp 1.51%
Commonwealth Bank of Australia 1.37%
Tokyo Electron Ltd 1.30%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VPL Vanguard FTSE Pacific ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Pacific Stock
Total return, 1 year +37.5% +24.8%
Expense ratio 0.44% 0.07%
Already in the S&P 500 40.2% 0.0%
Holdings 245 2343
Net assets, IBB as of Oct 27, 2026 and VPL as of Sep 30, 2026 $11.0bn $9.0bn

IBB and VPL on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VPL

VPL tracks an index of Pacific Stock. Over the year to Oct 28, 2026 it returned +24.8% with distributions reinvested. The prospectus expense ratio is 0.07% a year. By its holdings published by its issuer as of Sep 30, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 2,343 positions, with the top ten at 24.8%. It sat 7.2% below its high of Jun 22, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and VPL in the same category?
IBB is a thematic ETF and VPL is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VPL?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VPL +24.8%.
Which is cheaper, IBB or VPL?
VPL is cheaper, by 0.37 percentage points a year. That is about $37 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VPL overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 0% of VPL by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against VPL, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vpl

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