Data as of Oct 28, 2026.

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IBB vs URTH: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to URTH's +13.1%, and URTH charges 0.24% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $8.9bn on Oct 28, 2026 for iShares MSCI World ETF.

At a glance
+37.5%
IBB total return, 1 year
+13.1%
URTH total return, 1 year
0.44%
IBB expense ratio
0.24%
URTH expense ratio

Pair scorecard

URTH costs 0.20 points a year less; their one-year returns differ by 24.4 points; IBB is 1.3 times larger.

IBB vs URTH: Differences, Returns & Fees
MeasureIBBURTH
Return
Total return, 1 year+37.5%+13.1%
Benchmark
What it tracksBiotechMSCI World Index
Cost and size
Expense ratio0.44%0.24%
Net assets, as of Oct 27, 2026$11.0bn$8.8bn
Active share vs the S&P 50099%
Holdings
Holdings in common1%
Top ten holdings, share of the fund50%27.2%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, IBB and URTH hold 1% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first IBB URTH
AMGEN INC 8.20% 0.26%
GILEAD SCIENCES 8.56% 0.22%
VERTEX PHARMACEUTICALS 7.53% 0.14%
REGENERON PHARMACEUTICALS 5.64% 0.09%
ARGENX SE ADR 3.42% 0.06%
NATERA 3.85% 0.06%
ILLUMINA INC 2.93% 0.05%
BIOGEN 2.58% 0.04%
ALNYLAM PHARMACEUTICALS 2.11% 0.03%
GENMAB SPONSORED ADR 1.72% 0.03%
REVOLUTION MEDICINES 2.50% 0.03%
UNITED THERAPEUTICS 1.71% 0.03%
Only in one fund ↓
Only in IBB
MODERNA 5.29%
BEONE MEDICINES AG 2.15%
CHARLES RIVER LABORATORIES INTERNA 1.18%
EXELIXIS INC 1.09%
ASCENDIS PHARMA 1.06%
MEDPACE HOLDINGS 1.06%
HALOZYME THERAPEUTICS 1.01%
BRIDGEBIO PHARMA 0.85%
Only in URTH
APPLE 5.60%
NVIDIA 5.50%
MICROSOFT 4.12%
AMAZON.COM INC 2.69%
ALPHABET CLASS A 2.07%
BROADCOM INC 1.70%
ALPHABET CLASS C 1.62%
META PLATFORMS CLASS A 1.49%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF URTH iShares MSCI World ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the MSCI World
Total return, 1 year +37.5% +13.1%
Its benchmark over the same days not measured +13.4% (ACWI)
Gap to its benchmark not measured −0.3 pts vs ACWI
Expense ratio 0.44% 0.24%
Already in the S&P 500 40.2% 69.1%
Holdings 245 1254
Net assets, IBB as of Oct 27, 2026 and URTH as of Oct 28, 2026 $11.0bn $8.9bn

IBB and URTH on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

URTH

URTH tracks the MSCI World. Over the year to Oct 28, 2026 it returned +13.1% with distributions reinvested, against +13.4% for its benchmark, the MSCI All Country World Index. The prospectus expense ratio is 0.24% a year. By its holdings published by its issuer for Oct 27, 2026, 69% of the fund by weight is stocks the S&P 500 also holds, across 1,254 positions, with the top ten at 27.2%.

Questions people ask

Are IBB and URTH in the same category?
IBB is a thematic ETF and URTH is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or URTH?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and URTH +13.1%.
Which is cheaper, IBB or URTH?
URTH is cheaper, by 0.20 percentage points a year. That is about $20 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and URTH overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 69% of URTH by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against URTH, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-urth

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