Data as of Oct 28, 2026.

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Across categories

IBB vs VGK: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VGK's +10.4%, and VGK charges 0.06% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $29.6bn on Sep 30, 2026 for Vanguard FTSE Europe ETF.

At a glance
+37.5%
IBB total return, 1 year
+10.4%
VGK total return, 1 year
0.44%
IBB expense ratio
0.06%
VGK expense ratio

Pair scorecard

VGK costs 0.38 points a year less; their one-year returns differ by 27.1 points; VGK is 2.6 times larger.

IBB vs VGK: Differences, Returns & Fees
MeasureIBBVGK
Return
Total return, 1 year+37.5%+10.4%
Drawdown
Below its high6.1%, high on Aug 25, 2026
Benchmark
What it tracksBiotechFTSE Developed Europe All Cap Index
Cost and size
Expense ratio0.44%0.06%
Net assets, as of Sep 30, 2026$11.2bn$29.6bn
Active share vs the S&P 50099%
Holdings
Holdings in common1%
Top ten holdings, share of the fund50%19.0%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, IBB and VGK hold 1% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first IBB VGK
ARGENX SE ADR 3.42% 0.39%
GENMAB SPONSORED ADR 1.72% 0.14%
ABIVAX AMERICAN DEPOSITARY SHARES 0.44% 0.05%
EMERGENT BIOSOLUTIONS 0.02% 0.25%
CHARLES RIVER LABORATORIES INTERNA 1.18% 0.01%
LAKEFRONT BIOTHERAPEUTICS ADR NV 0.10% 0.01%
CARIS LIFE SCIENCES 0.30% 0.00%
AKERO THERAPEUTICS CVR 0.00% 0.02%
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ILLUMINA INC 2.93%
BIOGEN 2.58%
Only in VGK
ASML Holding NV 4.47%
HSBC Holdings PLC 2.19%
Roche Holding AG 1.89%
Novartis AG 1.72%
Shell PLC 1.64%
AstraZeneca PLC 1.56%
Nestle SA 1.51%
Siemens AG 1.45%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VGK Vanguard FTSE Europe ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of European Stock
Total return, 1 year +37.5% +10.4%
Expense ratio 0.44% 0.06%
Already in the S&P 500 40.2% 0.0%
Holdings 245 1245
Net assets, IBB as of Oct 27, 2026 and VGK as of Sep 30, 2026 $11.0bn $29.6bn

IBB and VGK on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VGK

VGK tracks an index of European Stock. Over the year to Oct 28, 2026 it returned +10.4% with distributions reinvested. The prospectus expense ratio is 0.06% a year. By its holdings published by its issuer as of Sep 30, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 1,245 positions, with the top ten at 19.0%. It sat 6.1% below its high of Aug 25, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and VGK in the same category?
IBB is a thematic ETF and VGK is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VGK?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VGK +10.4%.
Which is cheaper, IBB or VGK?
VGK is cheaper, by 0.38 percentage points a year. That is about $38 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VGK overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 0% of VGK by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against VGK, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vgk

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