Data as of Oct 28, 2026.

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IBB vs VOE: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VOE's +22.8%, and VOE charges 0.05% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $22.8bn on Sep 30, 2026 for Vanguard Morningstar Mid-Cap Value ETF.

At a glance
+37.5%
IBB total return, 1 year
+22.8%
VOE total return, 1 year
0.44%
IBB expense ratio
0.05%
VOE expense ratio

Pair scorecard

VOE costs 0.39 points a year less; their one-year returns differ by 14.7 points; VOE is 2.0 times larger.

IBB vs VOE: Differences, Returns & Fees
MeasureIBBVOE
Return
Total return, 1 year+37.5%+22.8%
Benchmark
What it tracksBiotechMorningstar US Mid Cap Value Index
Cost and size
Expense ratio0.44%0.05%
Net assets, as of Sep 30, 2026$11.2bn$22.8bn
Active share vs the S&P 50099%
Holdings
Holdings in common2%
Top ten holdings, share of the fund50%14.0%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

2%

By the books each fund has filed, IBB and VOE hold 2% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

2% in common

Positions both hold · largest shared weight first IBB VOE
REGENERON PHARMACEUTICALS 5.64% 0.65%
MODERNA 5.29% 0.59%
BIOGEN 2.58% 0.57%
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
AMGEN INC 8.20%
VERTEX PHARMACEUTICALS 7.53%
NATERA 3.85%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
REVOLUTION MEDICINES 2.50%
BEONE MEDICINES AG 2.15%
Only in VOE
Valero Energy Corp 1.90%
Marathon Petroleum Corp 1.89%
Phillips 66 1.73%
Hewlett Packard Enterprise Co 1.37%
Warner Bros Discovery Inc 1.25%
SLB Ltd 1.23%
Target Corp 1.21%
Cummins Inc 1.21%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VOE Vanguard Morningstar Mid-Cap Value ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Mid-Cap Value
Total return, 1 year +37.5% +22.8%
Expense ratio 0.44% 0.05%
Already in the S&P 500 40.2% 96.0%
Holdings 245 169
Net assets, IBB as of Oct 27, 2026 and VOE as of Sep 30, 2026 $11.0bn $22.8bn

IBB and VOE on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VOE

VOE tracks an index of Mid-Cap Value. Over the year to Oct 28, 2026 it returned +22.8% with distributions reinvested. The prospectus expense ratio is 0.05% a year. By its holdings published by its issuer as of Sep 30, 2026, 96% of the fund by weight is stocks the S&P 500 also holds, across 169 positions, with the top ten at 14.0%.

Questions people ask

Are IBB and VOE in the same category?
IBB is a thematic ETF and VOE is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VOE?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VOE +22.8%.
Which is cheaper, IBB or VOE?
VOE is cheaper, by 0.39 percentage points a year. That is about $39 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VOE overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 96% of VOE by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against VOE, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-voe

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