As of . Rebuilt every trading night.
The innovation ETFs least like the S&P 500
Every fund here is sold on innovation, and they differ in how much of the index they hand you back. The one at the top is the one adding the most that is new.
| # | Ticker | Fund | Weight in S&P 500 companies | Active share | Net assets | Fee |
|---|---|---|---|---|---|---|
| 1 | GXDW | Global X Dorsey Wright Thematic ETF | 0.0% | 100.0% | $6m | 0.50% |
| 2 | LFSC | F/m Emerald Life Sciences Innovation ETF | 0.0% | 100.0% | $105m | 0.54% |
| 3 | LENS | Sarmaya Thematic ETF | 21.7% | 97.9% | $53m | 0.79% |
| 4 | FMED | Fidelity Disruptive Medicine ETF | 25.4% | 97.1% | $52m | 0.50% |
| 5 | FITE | State Street(R) SPDR(R) S&P Kensho Futur | 27.1% | 95.3% | $149m | 0.45% |
| 6 | HTEC | ROBO Global(R) Healthcare Technology and | 31.8% | 97.9% | $53m | 0.68% |
| 7 | INVN | Alger Russell Innovation ETF | 32.5% | 98.5% | $10m | 0.55% |
| 8 | GTEK | Goldman Sachs Future Tech Leaders Equity | 33.5% | 96.4% | $237m | 0.75% |
| 9 | BULD | Pacer BlueStar Engineering the Future ET | 35.8% | 97.2% | $5m | 0.49% |
| 10 | ARKK | ARK Innovation ETF | 36.2% | 85.7% | $9.3bn | 0.75% |
| 11 | DTRE | First Trust Alerian Disruptive Technolog | 40.1% | 99.4% | $14m | 0.60% |
| 12 | FDFF | Fidelity Disruptive Finance ETF | 45.1% | 97.4% | $47m | 0.50% |
| 13 | QQQJ | Invesco NASDAQ Next Gen 100 ETF | 46.2% | 98.6% | $1.2bn | 0.15% |
| 14 | TMAT | Main Thematic Innovation ETF | 46.4% | 91.5% | $211m | 0.82% |
| 15 | ANEW | ProShares MSCI Transformational Changes | 51.0% | 76.2% | $8m | 0.45% |
Method
The 29 of 30 ETFs in the broad innovation and megatrends theme with a filed book, least overlap first, each measured against the S&P 500 holdings ETFIQ reads for the same date. Across the funds listed here the weight held in S&P 500 companies runs from 0.0% to 51.0%. A thematic fund is worth its fee only for the part of it you do not already own. The ranking is the published field sorted, nothing else: no scoring, no weighting and no view on any fund. Every fund ETFIQ covers in this category is eligible, including funds that have closed, because leaving them out would flatter the category.
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Where these figures came from
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A ranking is not a recommendation and no order on this site is an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources
Cite this page. ETFIQ, The innovation ETFs least like the S&P 500, ranked by the share of the fund by weight that is held in S&P 500 companies, data as of Sep 18, 2026. https://etfiq.com/rankings/themes-off-index-innovation Free to use with attribution; the underlying files are at Open data.