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The innovation ETFs that returned most

Funds sold on one theme can hold different companies, so a year apart at the top and the bottom of this list is a difference in what they own rather than in the theme.

The innovation ETFs that returned most, ranked by total return with distributions reinvested, as of Sep 18, 2026. Source: ETFIQ.
#TickerFundTotal return, 1Yvs the S&P 500Weight in S&P 500 companiesFee
1LFSCF/m Emerald Life Sciences Innovation ETF+53.0%+36.5 pts0.0%0.54%
2CARZFirst Trust S-Network Future Vehicles & +50.4%+33.9 pts51.5%0.70%
3LENSSarmaya Thematic ETF+46.4%+29.8 pts21.7%0.79%
4GTEKGoldman Sachs Future Tech Leaders Equity+43.6%+27.1 pts33.5%0.75%
5HTECROBO Global(R) Healthcare Technology and+37.8%+21.3 pts31.8%0.68%
6FDTXFidelity Disruptive Technology ETF+37.2%+20.7 pts71.1%0.50%
7BULDPacer BlueStar Engineering the Future ET+37.2%+20.6 pts35.8%0.49%
8FITEState Street(R) SPDR(R) S&P Kensho Futur+30.7%+14.1 pts27.1%0.45%
9FMEDFidelity Disruptive Medicine ETF+28.3%+11.7 pts25.4%0.50%
10XTiShares Future Exponential Technologies +24.4%+7.8 pts64.5%0.46%
11QQQJInvesco NASDAQ Next Gen 100 ETF+22.4%+5.8 pts46.2%0.15%
12AOTGAOT Growth and Innovation ETF+22.3%+5.8 pts77.4%0.75%
13INVNAlger Russell Innovation ETF+20.7%+4.2 pts32.5%0.55%
14ILDRFirst Trust Innovation Leaders ETF+19.9%+3.3 pts65.8%0.75%
15TEKYLazard Next Gen Technologies ETF+16.8%+0.2 pts51.5%0.50%

Method

The 27 of 30 ETFs in the broad innovation and megatrends theme with a full year of trading, highest first, each over the same year to Sep 18, 2026 with distributions reinvested. Across the funds listed here the one year total return runs from 16.8% to 53.0%. A year is a year. It says what happened and nothing about what happens next. The ranking is the published field sorted, nothing else: no scoring, no weighting and no view on any fund. Every fund ETFIQ covers in this category is eligible, including funds that have closed, because leaving them out would flatter the category.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

A ranking is not a recommendation and no order on this site is an opinion. ETFIQ is an independent publisher, not an adviser. Standards and sources

Cite this page. ETFIQ, The innovation ETFs that returned most, ranked by total return with distributions reinvested, data as of Sep 18, 2026. https://etfiq.com/rankings/themes-best-year-innovation Free to use with attribution; the underlying files are at Open data.